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Dense Breast Tissue Not Problematic for Molecular Breast Imaging

By MedImaging International staff writers
Posted on 20 Feb 2014

Image: The Dilon molecular breast imaging detector is available in two sizes: the standard Dilon 6800: 15 x 20 cm, and the Dilon 6800 Acella: (20 x 25 cm. The technology allows imaging close to the chest wall, thereby minimizing dead space with a portable gantry eliminating the need for installation (Photo courtesy of Dilon).

Molecular breast imaging (MBI) has been found to detect cancer independently of breast tissue density. These new findings were gathered from over 300 breast cancer patients that underwent the MBI/BSGI procedure. The same high rate of 95% of breast cancer detection was validated for women with or without breast density.

This significant finding was published in January 2014 issue of the American Journal of Roentgenology by a group of radiologists and surgeons at the George Washington University Medical Center (Washington DC, USA). “This study indicates that breast tissue density is simply a non-issue for MBI/BSGI,” said Douglas Kieper, vice president for science and technology at Dilon Technologies (Newport News, VA, USA), a developer of MBI systems. “This is great news for patients who have an inconclusive mammogram due to breast density, implants, or scarring.”

A range of studies has shown that mammography is less effective in patients with dense breast tissue, missing as much as 50% of breast cancers. Breast MRI is known to be more sensitive than mammography or ultrasound in women with dense breasts, but at a much higher cost per scan. Conversely, MBI, also known as breast-specific gamma imaging (BSGI), is an imaging procedure that has been demonstrated in several clinical studies to be better than mammography or ultrasound for detecting breast cancer, particularly in women with dense breasts. Moreover, the MBI/BSGI procedure can be conducted at one-third of the cost of an MRI and it can be offered to patients who cannot undergo an MRI scan, such as women with pacemakers, those who are on dialysis or are claustrophobic.

For years, women who have dense breasts were typically oblivious of their breast density or of the possibility that their negative mammogram might be missing cancers. That is until recently, as several states in the United States have passed legislation requiring breast centers to inform patients with dense breasts that their mammogram might be inconclusive. The state of Oregon new breast density law includes BSGI as one of the technology alternative that should be considered for patients who receive a dense-breast notification from their doctor. The state of Indiana goes beyond that by requiring state employee-health plans to cover additional medical examination for women with high breast density.

Dilon Technologies, Inc. is a developer of diagnostic imaging with the Dilon molecular imaging systems, high-resolution, small field-of-view general-use imaging cameras, optimized to perform molecular breast imaging (MBI/BSGI) and localization for MBI-guided breast biopsy. Dilon’s surgical imaging products, the Navigator probes, are one of the most widely used gamma probes for cancer surgery. The gamma probes offer an upgrade option for three-dimensional (3D) tumor imaging and navigation with SurgicEye’s (Munich, Germany) declipseSPECT (single photon emission computed tomography) camera.

Dilon is the exclusive international distributor of Digirad’s (Atlanta, GA, USA) Cardius cardiac and ergo general molecular imaging cameras that provide excellent image quality and increased patient comfort with a compact, open design.

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George Washington University Medical Center
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63 (434.87548828125): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

64 (55.074691772461): select jos_twitters.link from jos_twitters where cat=10

65 (30.040740966797): select jos_facebook.link from jos_facebook where cat=10

66 (45.061111450195): select jos_google_plus.link from jos_google_plus where cat=10

67 (51.975250244141): select jos_linkedin.link from jos_linkedin where cat=10

68 (53.882598876953): SELECT fid FROM jos_deeppockets WHERE id=294750832 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294750832 AND published='1' LIMIT 1

69 (49.114227294922): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

70 (436.06758117676): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294750832 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (354.05158996582): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294750832 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (!!!!! 7959.8426818848): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (54.121017456055): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (49.829483032227): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (49.829483032227): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294750832 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (28.133392333984): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294750832 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (33.140182495117): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (56.028366088867): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

105 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

106 (110.86463928223): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294750832 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (72.956085205078): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294750832 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

109 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

110 (50.067901611328): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294750832 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (534.0576171875): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294750832 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (603.91426086426): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (398.15902709961): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

115 (94.175338745117): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

116 (126.12342834473): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

117 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

118 (59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

119 (36.001205444336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

120 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

121 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

122 (453.94897460938): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294750832 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294750832 AND type='deeppockets_item' AND published='1' LIMIT 1

123 (!!!!! 401066.06483459): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

124 (107.0499420166): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

125 (411.03363037109): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

126 (60.081481933594): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

127 (358.10470581055): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

128 (65.088272094727): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

129 (285.86387634277): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

130 (60.081481933594): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

131 (558.85314941406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

132 (511.16943359375): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

133 (308.99047851562): SELECT name FROM jos_deeppockets WHERE id=213

134 (43.869018554688): SELECT name FROM jos_deeppockets WHERE id=213

135 (562.90626525879): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

136 (531.91184997559): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

137 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

138 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

139 (407.93418884277): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

140 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

141 (92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

142 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

143 (!!!!! 1358.9859008789): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

144 (120.87821960449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

145 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

146 (62.942504882812): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294750832 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294750832 AND type='deeppockets_item' AND published='1' LIMIT 1

147 (43.869018554688): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

148 (41.007995605469): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

149 (59.127807617188): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

150 (161.17095947266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

151 (87.976455688477): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294750832 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294750832 AND published='1' LIMIT 1

152 (115.15617370605): select jos_twitters.link from jos_twitters where cat=10

153 (32.901763916016): select jos_facebook.link from jos_facebook where cat=10

154 (31.948089599609): select jos_google_plus.link from jos_google_plus where cat=10

155 (31.948089599609): select jos_linkedin.link from jos_linkedin where cat=10

156 (365.9725189209): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

157 (!!!!! 1576.9004821777): insert into jos_banners_delta values (14615,'2025-06-19 12:20:49','216.73.216.120','view'),(14202,'2025-06-19 12:20:49','216.73.216.120','view'),(14203,'2025-06-19 12:20:49','216.73.216.120','view')

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