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PET/MRI Imaging Technology Shows Promise

By MedImaging International staff writers
Posted on 05 Sep 2013

Image: The Philips Ingenuity TF PET/MRI system (Photo courtesy of the University Hospitals Case Medical Center).

Initial clinical experience in diagnosing and staging cancer patients with novel hybrid imaging modality technology shows favorable results.

Researchers at University Hospitals Case Medical Center (Cleveland, OH, USA), in collaboration with researchers from Philips Healthcare (Eindhoven,The Netherlands) examined 145 cancer patients with a double-scanning protocol of Positron Emission Tomography (PET)/ Computerized tomography (CT) followed by a PET/ Magnetic Resonance Imaging (MRI) performed on the Philips Ingenuity TF PET/MRI system, which brings together the complementary capabilities of both to better visualize both functional and anatomical information, and to superimpose this information in a combined digital image.

The researchers found that PET/MRI provided benefits in the diagnosis, staging, and treatment planning of colorectal cancers, cervical, uterine, ovarian, and pancreatic cancers, as well as in the diagnostic management of pediatric and young adult patients. PET/MRI combines high anatomic detail as well as bio-chemical and functional information provided by MRI with the metabolic, molecular, and physiologic information from PET. The technology fuses the images to more precisely pinpoint cancer locations and improve the accuracy of disease staging.

The study also outlines the considerations of reduction in overall radiation imaging exposure with PET/MRI versus other imaging technologies, offering a potential to decrease radiation exposure by replacing the CT component in PET/CT with MRI. According to the researchers, this may especially be an issue in pediatric and young adult patients with need for repetitive follow up imaging. The study outlining the initial clinical experience was published in the September 2013 issue of Current Radiology Reports.

“Our preliminary experience with this new diagnostic imaging technology proves that it is promising for oncologic applications,” said lead author radiologist Karin Herrmann, MD. “PET/MRI enhanced our ability to detect malignant areas and more accurately and confidently diagnose several types of cancers, potentially providing physicians with the ability to improve treatment planning and better monitoring of the disease.”

“This hybrid scanner has the potential to improve patient care by increasing understanding of the causes, effects, and development of disease processes to better diagnose cancer and various other diseases,” added said study coauthor nuclear radiologist Norbert Avril, MD. “We are very excited to be among the first to be able to help establish guidelines of how best to use this technology to guide physicians on the value of the PET/MRI in diagnosing and staging various forms of cancer. Our initial experience has shown that it may be a very important cancer-fighting tool.”

Related Links:
University Hospitals Case Medical Center
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68 (37.193298339844): SELECT fid FROM jos_deeppockets WHERE id=294748098 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294748098 AND published='1' LIMIT 1

69 (46.014785766602): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

70 (338.07754516602): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294748098 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (226.97448730469): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294748098 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (39.100646972656): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (66.995620727539): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (41.961669921875): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294748098 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (27.894973754883): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294748098 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (32.186508178711): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (48.87580871582): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (88.930130004883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

105 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

106 (113.01040649414): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294748098 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (60.081481933594): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294748098 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

109 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

110 (63.896179199219): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294748098 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (903.12957763672): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294748098 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (609.15946960449): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (408.88786315918): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (90.122222900391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

115 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

116 (169.03877258301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

117 (49.829483032227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

118 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

119 (36.954879760742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

120 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

121 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

122 (428.91502380371): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294748098 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294748098 AND type='deeppockets_item' AND published='1' LIMIT 1

123 (!!!!! 390316.00952148): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

124 (82.015991210938): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

125 (483.98971557617): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

126 (56.982040405273): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

127 (367.16461181641): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

128 (72.956085205078): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

129 (216.00723266602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

130 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

131 (464.20097351074): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

132 (423.90823364258): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

133 (250.81634521484): SELECT name FROM jos_deeppockets WHERE id=213

134 (35.04753112793): SELECT name FROM jos_deeppockets WHERE id=213

135 (605.10635375977): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

136 (476.83715820312): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

137 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

138 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

139 (293.97010803223): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

140 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

141 (48.160552978516): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

142 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

143 (!!!!! 1257.1811676025): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

144 (81.777572631836): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

145 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

146 (54.121017456055): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294748098 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294748098 AND type='deeppockets_item' AND published='1' LIMIT 1

147 (33.855438232422): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

148 (36.001205444336): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

149 (36.001205444336): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

150 (132.08389282227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

151 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748098 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748098 AND published='1' LIMIT 1

152 (121.11663818359): select jos_twitters.link from jos_twitters where cat=10

153 (29.087066650391): select jos_facebook.link from jos_facebook where cat=10

154 (27.894973754883): select jos_google_plus.link from jos_google_plus where cat=10

155 (26.226043701172): select jos_linkedin.link from jos_linkedin where cat=10

156 (246.04797363281): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

157 (!!!!! 1298.9044189453): insert into jos_banners_delta values (14615,'2025-06-19 21:20:38','216.73.216.120','view'),(14202,'2025-06-19 21:20:38','216.73.216.120','view'),(14203,'2025-06-19 21:20:38','216.73.216.120','view')

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