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Body GPS, Real-Time Tracking System Used for Prostate Radiotherapy

By MedImaging International staff writers
Posted on 22 Oct 2012

Image: A diagram of the Calypso 4-D localization system, showing the electromagnetic transponders (Photo courtesy of Varian Medical Systems).

New technology has been developed to provide real-time tracking of tumors during prostate cancer radiotherapy treatments. The first such system to be installed in the United Kingdom, the real-time tracking method has been used to enhance the effectiveness of treatments for more than 20 prostate cancer patients at the clinic.

“This really is the gold standard for real-time tracking and we are finding that as patients learn about the system, an increasing number are requesting that we make use of Calypso transponders during their treatments,” said Neil Livingstone, treatment superintendent at Harley Street Clinic (London, UK). “We hope that an increase in precision may help minimize radiation to healthy tissue while giving our clinicians additional confidence to deliver higher doses.”

Clinicians at the Harley Street Clinic are using the real-time tracking capabilities of Calypso to lessen the amount of healthy tissue exposed to the treatment beam. Three Calypso transponders are inserted into the prostate, where they provide continuous real-time data. The position of the markers is monitored continuously throughout a treatment session to help keep the beam on target. If the targeted region moves outside the treatment beam, the treatment is automatically stopped.

Another benefit of the system, according to Mr. Livingstone, is that patients no longer need to be imaged on a daily basis, avoiding the need for additional X-ray exposure during conventional imaging. “We have great faith in the real-time tracking abilities of Calypso, which means we no longer need to image our patients as often as before,” he added.

Similar to a GPS tracking system in a car can identify where the car is at all times in relation to its destination, Calypso “GPS for the body” provides continuous real-time information as to the precise location of the prostate. The prostate can shift by as much as several millimeters during a radiotherapy treatment session. Varian Medical Systems’ (Palo Alto, CA, USA) Calypso technology enables clinicians to track the prostate in real time during treatment, in order to help enhance treatment precision. There are more than 100 Calypso installations globally and more than 15,000 patients worldwide have been treated using the system.

Recent findings demonstrated that the use of Calypso real-time tracking during radiotherapy treatments for prostate cancer resulted in a considerable decrease in most of the serious treatment-related side effects that were studied.

Related Links:
Harley Street Clinic
Varian Medical Systems

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69 (46.014785766602): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

70 (406.02684020996): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294743023 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (308.99047851562): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294743023 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (47.922134399414): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (150.20370483398): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (53.882598876953): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (60.081481933594): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (66.995620727539): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (48.87580871582): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (72.002410888672): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (66.995620727539): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (66.995620727539): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (87.02278137207): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (72.002410888672): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294743023 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (44.822692871094): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294743023 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (46.968460083008): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

105 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

106 (67.949295043945): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294743023 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (51.021575927734): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294743023 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (106.0962677002): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

109 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

110 (71.048736572266): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294743023 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (730.99136352539): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294743023 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (669.00253295898): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (450.13427734375): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (102.04315185547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

115 (97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

116 (79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

117 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

118 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

119 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

120 (316.85829162598): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 20833.015441895): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (149.96528625488): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

123 (70.095062255859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

124 (488.0428314209): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294743023 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294743023 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 586408.13827515): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (101.08947753906): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (51.975250244141): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (105.14259338379): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (39.815902709961): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (54.121017456055): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (37.908554077148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (481.12869262695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (375.03242492676): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (243.18695068359): SELECT name FROM jos_deeppockets WHERE id=213

136 (68.187713623047): SELECT name FROM jos_deeppockets WHERE id=213

137 (530.00450134277): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (427.9613494873): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

140 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

141 (!!!!! 28115.034103394): TRUNCATE TABLE jos_trademed_module

142 (278.94973754883): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294743023 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (165.93933105469): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294743023 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (569.10514831543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (81.062316894531): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

147 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

148 (!!!!! 1398.8018035889): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

150 (179.05235290527): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

151 (44.107437133789): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294743023 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294743023 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (31.948089599609): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

153 (28.848648071289): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

154 (29.087066650391): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (115.87142944336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

156 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743023 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743023 AND published='1' LIMIT 1

157 (74.863433837891): select jos_twitters.link from jos_twitters where cat=10

158 (36.954879760742): select jos_facebook.link from jos_facebook where cat=10

159 (36.001205444336): select jos_google_plus.link from jos_google_plus where cat=10

160 (37.193298339844): select jos_linkedin.link from jos_linkedin where cat=10

161 (360.96572875977): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 1550.9128570557): insert into jos_banners_delta values (14615,'2025-06-20 11:01:37','216.73.216.120','view'),(14202,'2025-06-20 11:01:37','216.73.216.120','view'),(14203,'2025-06-20 11:01:37','216.73.216.120','view')

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