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PET Myocardial Perfusion Imaging Agent Evaluated as Tool to Detect Coronary Artery Disease

By MedImaging International staff writers
Posted on 16 Jun 2011

Positron emission tomography (PET) with the imaging agent flurpiridaz F18 has the potential to be a new clinical tool for the evaluation of myocardial perfusion that may better evaluate patients with known or suspected coronary artery disease (CAD).

Lantheus Medical Imaging, Inc. (North Billerica, MA, USA), a worldwide developer of diagnostic imaging systems, reported that full results from the phase 2 clinical trial for the assessment of myocardial perfusion using PET imaging of flurpiridaz F18 in patients with suspected or known CAD were presented at the International Conference of Noninvasive Cardiovascular Imaging (ICNC10-Nuclear Cardiology and Cardiac CT) Conference, held May 15-18, 2011, in Amsterdam, The Netherlands. The full phase 2 data set was presented in a late-breaking presentation by Jamshid Maddahi, MD, FACC, professor of molecular and medical pharmacology (nuclear medicine) and medicine (cardiology) at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA; USA), and the lead investigator of the study.

"The preliminary phase 2 data of flurpiridaz F18 have been promising, and we are very excited to share the full data results with the scientific community at ICNC10," said Don Kiepert, president and chief executive officer of Lantheus Medical Imaging. "PET myocardial perfusion imaging with flurpiridaz F18 has the potential to better evaluate patients with known or suspected coronary artery disease than SPECT [single photon emission computed tomography] imaging, and we look forward to initiating phase 3 clinical trials of this important new clinical tool in the second quarter of this year."

In March 2011, Lantheus received Special Protocol Assessment approval from the US Food and Drug Administration (FDA) for the phase 3 trial of flurpiridaz F18. The phase 3 open-label, multicenter trial will evaluate myocardial perfusion using PET imaging of flurpiridaz F18 in approximately 1,350 patients with suspected or known CAD. The chief objective of the study will be to assess the sensitivity and specificity of PET imaging with flurpiridaz F18 as compared to SPECT imaging.

Flurpiridaz F18 injection, a fluorine 18-labeled agent that binds to mitochondrial complex 1 (MC-1), was designed to be an innovative myocardial perfusion PET imaging agent for the diagnosis of CAD, which is the most common form of heart disease, affecting approximately 16.8 million people in the United States.

Myocardial perfusion imaging (MPI) is a noninvasive test that utilizes a small amount of radioactive material (radiopharmaceutical) injected into the body to depict the distribution of blood flow to the heart. MPI is used to identify areas of reduced perfusion to the heart muscle. The test is typically conducted under both rest and stress conditions, after which physicians examine and compare the two scans and predict whether the patient has significant coronary artery disease. Although single-photon emission computer tomography (SPECT) is most typically used for MPI, PET imaging has gained considerable support and use in the field of cardiovascular imaging, as it offers many advantages to SPECT, including higher spatial and contrast resolution, which results in higher image quality and improved diagnostic accuracy, accurate attenuation correction, and risk stratification.

Related Links:
Lantheus Medical Imaging
University of California, Los Angeles

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62 (!!!!! 7055.9978485107): SELECT fid FROM jos_deeppockets WHERE id=294735611 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294735611 AND published='1' LIMIT 1

63 (!!!!! 4627.2277832031): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

64 (!!!!! 7510.9004974365): select jos_twitters.link from jos_twitters where cat=10

65 (51.975250244141): select jos_facebook.link from jos_facebook where cat=10

66 (406.98051452637): select jos_google_plus.link from jos_google_plus where cat=10

67 (65.088272094727): select jos_linkedin.link from jos_linkedin where cat=10

68 (303.03001403809): SELECT fid FROM jos_deeppockets WHERE id=294735611 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294735611 AND published='1' LIMIT 1

69 (41.961669921875): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

70 (833.03451538086): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294735611 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (604.86793518066): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294735611 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (61.988830566406): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (776.05247497559): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (282.04917907715): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (222.92137145996): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (62.942504882812): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (78.916549682617): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (!!!!! 3391.9811248779): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (105.14259338379): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (61.03515625): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (404.83474731445): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (272.98927307129): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (53.167343139648): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (375.98609924316): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (930.0708770752): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294735611 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (304.9373626709): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294735611 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (!!!!! 1463.8900756836): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 2985.954284668): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (62.942504882812): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (!!!!! 1307.0106506348): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (!!!!! 2275.9437561035): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (!!!!! 1584.0530395508): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (!!!!! 1066.2078857422): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (218.86825561523): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (!!!!! 1441.0018920898): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (!!!!! 1513.0043029785): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (303.98368835449): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (507.11631774902): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (158.07151794434): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (!!!!! 2171.9932556152): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (76.055526733398): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 8425.9510040283): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

105 (!!!!! 2170.0859069824): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

106 (966.07208251953): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294735611 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (!!!!! 1260.9958648682): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294735611 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 7399.7974395752): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

109 (!!!!! 1336.0977172852): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

110 (108.95729064941): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294735611 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 1230.001449585): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294735611 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 7337.0933532715): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (!!!!! 2094.9840545654): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (256.06155395508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

115 (626.0871887207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

116 (475.88348388672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

117 (90.837478637695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

118 (633.00132751465): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

119 (241.99485778809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

120 (403.88107299805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

121 (849.96223449707): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

122 (!!!!! 3324.9855041504): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 64728.021621704): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 2641.9162750244): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294735611 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294735611 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 28903.961181641): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (82.015991210938): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (89.883804321289): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (44.822692871094): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (778.9134979248): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (230.07392883301): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (427.9613494873): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (169.03877258301): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (977.99301147461): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (590.08598327637): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (549.0779876709): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (318.05038452148): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (48.160552978516): SELECT name FROM jos_deeppockets WHERE id=213

138 (51.975250244141): SELECT name FROM jos_deeppockets WHERE id=213

139 (!!!!! 2346.9924926758): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (890.97023010254): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (!!!!! 2711.0576629639): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

142 (159.97886657715): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

143 (!!!!! 19078.969955444): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 10621.070861816): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294735611 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (!!!!! 1450.0617980957): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294735611 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (712.87155151367): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (119.92454528809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (!!!!! 5095.9587097168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

149 (120.87821960449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

150 (!!!!! 5666.0175323486): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (!!!!! 3799.2000579834): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

152 (!!!!! 3940.8206939697): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

153 (653.02848815918): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294735611 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294735611 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (68.902969360352): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

155 (42.200088500977): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

156 (71.048736572266): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 1965.9996032715): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

158 (!!!!! 2151.0124206543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294735611 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294735611 AND published='1' LIMIT 1

159 (77.009201049805): select jos_twitters.link from jos_twitters where cat=10

160 (35.04753112793): select jos_facebook.link from jos_facebook where cat=10

161 (32.901763916016): select jos_google_plus.link from jos_google_plus where cat=10

162 (33.140182495117): select jos_linkedin.link from jos_linkedin where cat=10

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