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Partnership to Develop Injectable Tracer for Diagnosing, Tumor Surgery

By MedImaging International staff writers
Posted on 06 Apr 2011

Five French partners are developing an injectable tracer that can provide both nuclear imaging in the preoperative evaluation of tumors and optical imaging during ablation or biopsy.

CEA-Leti (Grenoble, France) and three other French partners reported that the three-year Nano-ENO project is developing a specific tracer using a patented organic nanocarrier (Lipidot). To improve its targeting capacities, a peptide molecule that recognizes specific types of cancer will also be grafted to the Lipidots. CEA-Leti conducts research and develops nanoelectronics and technology for healthcare. The Nano-Eno project includes Advanced Accelerator Applications (Saint-Genis-Pouilly, France), Fluoptics (Grenoble, France), and VetAgro Sup (Marcy-l'Etoile, France), as well as Frédéric Joliot Hospital (Orsay, France).

When treating cancer, clinicians utilize several diagnostic tools and surgical aids, including positron emission tomography (PET) scan and fluorescence imaging. A PET scan is a nuclear imaging technology that allows radiologists to measure the metabolic activity of an organ by injecting a radiotracer and then examining the gamma rays that are emitted as the tracer disintegrates.

Fluorescence imaging is a comparatively new technology that combines the use of a florescent tracer with near-infrared spectroscopy (NIRS). The resulting real-time images help surgeons obtain cleaner margins during surgery and therefore reduce the risk of recurrence.

The nuclear imaging markers used in a PET scan help provide high-resolution images, while optical contrast agents facilitate the identification of tumor cells in real-time. Combining these imaging technologies makes it possible to confirm that the tumors being operated on correspond to the tumors identified in the preoperative studies. It also allows for a more thorough procedure to be performed with reduced overall surgical time; not only can the surgeon perform more rapidly and with greater precision, but the entire operation is streamlined, allowing for a more efficient use of operating rooms and surgical staff.

This project will receive support from the Cancéropôle Lyon Auvergne Rhône Alpes (CLARA; France) Preuve de Concept (Proof of Concept) initiative for three years.

CEA is a French government-funded technologic research organization. A prominent player in the European research area, it is involved in setting up collaborative projects with many partners worldwide. The CEA is based in 10 research centers in France, each specializing in specific fields. The laboratories are located in the Paris region, the Rhône-Alpes, the Rhône valley, the Provence-Alpes-Côte d'Azur region, Aquitaine, Central France, and Burgundy.

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62 (116.10984802246): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

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64 (!!!!! 3785.8486175537): SELECT fid FROM jos_deeppockets WHERE id=294734356 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294734356 AND published='1' LIMIT 1

65 (!!!!! 4062.1757507324): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

66 (!!!!! 2490.9973144531): select jos_twitters.link from jos_twitters where cat=10

67 (75.817108154297): select jos_facebook.link from jos_facebook where cat=10

68 (37.193298339844): select jos_google_plus.link from jos_google_plus where cat=10

69 (30.994415283203): select jos_linkedin.link from jos_linkedin where cat=10

70 (46.968460083008): SELECT fid FROM jos_deeppockets WHERE id=294734356 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294734356 AND published='1' LIMIT 1

71 (38.14697265625): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

72 (589.13230895996): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294734356 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (417.94776916504): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294734356 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

74 (74.148178100586): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

75 (844.00177001953): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (66.041946411133): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (!!!!! 1053.0948638916): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (48.160552978516): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (63.896179199219): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (89.883804321289): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (438.92860412598): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294734356 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (!!!!! 2903.938293457): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294734356 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

91 (!!!!! 1901.1497497559): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

92 (!!!!! 1550.9128570557): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (69.141387939453): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (327.11029052734): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (47.206878662109): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (64.13459777832): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (856.87637329102): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (!!!!! 2950.90675354): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (746.01173400879): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (585.07919311523): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (213.1462097168): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (560.04524230957): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (!!!!! 1369.9531555176): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

107 (874.04251098633): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

108 (452.99530029297): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294734356 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (!!!!! 1887.0830535889): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294734356 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

110 (!!!!! 5025.1483917236): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

111 (!!!!! 2059.9365234375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

112 (918.14994812012): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294734356 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (!!!!! 1282.9303741455): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294734356 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

114 (!!!!! 1083.1356048584): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (618.93463134766): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

116 (107.0499420166): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

117 (96.08268737793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

118 (504.97055053711): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

119 (415.08674621582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

120 (!!!!! 1182.0793151855): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

121 (279.90341186523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

122 (!!!!! 1202.1064758301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

123 (195.02639770508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

124 (788.92707824707): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

125 (!!!!! 69897.890090942): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

126 (!!!!! 1559.0190887451): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294734356 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294734356 AND type='deeppockets_item' AND published='1' LIMIT 1

127 (!!!!! 30199.05090332): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (77.962875366211): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

129 (61.988830566406): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (51.975250244141): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

131 (84.161758422852): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (46.014785766602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

133 (446.08116149902): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (61.988830566406): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

135 (69.141387939453): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (56.028366088867): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

137 (526.18980407715): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (905.99060058594): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

139 (647.06802368164): SELECT name FROM jos_deeppockets WHERE id=213

140 (!!!!! 2490.9973144531): SELECT name FROM jos_deeppockets WHERE id=213

141 (!!!!! 2057.0755004883): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (875.94985961914): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

143 (123.97766113281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

144 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

145 (!!!!! 7423.1624603271): TRUNCATE TABLE jos_trademed_module

146 (!!!!! 3337.1448516846): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294734356 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (123.97766113281): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294734356 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

148 (!!!!! 3046.989440918): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (120.16296386719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

150 (115.15617370605): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

151 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

152 (!!!!! 1671.0758209229): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

153 (!!!!! 2197.9808807373): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

154 (!!!!! 1352.071762085): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

155 (60.796737670898): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294734356 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294734356 AND type='deeppockets_item' AND published='1' LIMIT 1

156 (43.153762817383): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

157 (36.954879760742): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

158 (43.869018554688): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

159 (167.1314239502): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

160 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734356 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734356 AND published='1' LIMIT 1

161 (!!!!! 4781.0077667236): select jos_twitters.link from jos_twitters where cat=10

162 (122.0703125): select jos_facebook.link from jos_facebook where cat=10

163 (49.829483032227): select jos_google_plus.link from jos_google_plus where cat=10

164 (38.862228393555): select jos_linkedin.link from jos_linkedin where cat=10

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