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First Skin Cancer Patients Treated with Electronic Brachytherapy Technology

By MedImaging International staff writers
Posted on 12 Aug 2009

A new electronic brachytherapy system delivers a high therapeutic dose to a cancerous tumor while sparing neighboring healthy tissue by using a miniaturized X-ray source instead of radioactive isotopes.

Earlier in July 2009, the University of Wisconsin (UW) Cancer Center Riverview became the first medical facility in the world to treat patients with a breakthrough treatment of skin cancer. Located within Riverview Hospital, Wisconsin Rapids, the UW Cancer Center Riverview is the first to treat skin cancer patients with the U.S. Food and Drug Administration- (FDA)-cleared Axxent electronic brachytherapy system, developed by Xoft, Inc. (Sunnyvale, CA, USA).

The Riverview Center initiated treatments on three patients with nonmelanoma skin cancers under the direction of James S. Welsh, M.S., M.D., the center's radiation oncologist and a clinical professor in the department of human oncology and medical physics at the University of Wisconsin, Madison. Dr. Welsh collaborated with Yi Rong, Ph.D., chief medical physicist at UW Cancer Center Riverview, on the planning and delivery of the treatments. Dr. Rong discussed this process at the 51st annual meeting of the American Association of Physicists in Medicine on July 26-30, 2009, in Anaheim, CA, USA.

Skin cancer is the most common cancer in the United States with more than one million cases diagnosed annually and results in more than 10,000 deaths yearly, according to the U.S. National Cancer Institute (Bethesda, MD, USA). However, if diagnosed and treated early, most cases of skin cancer can be cured. While melanoma is the most serious form of skin cancers, it accounts for less than 10% of all cases. Nonmelanoma skin cancers, such as basal cell carcinoma and squamous cell carcinoma, represent the majority of all new cases.

"We are dedicated to bringing the most complete and innovative cancer care to patients in central Wisconsin, which is why we are so excited to introduce electronic brachytherapy as a treatment for nonmelanoma skin cancer,” said Dr. Welsh. "By using the Xoft skin applicator, which just became available in June [2009], we shorten the course of treatment and precisely conform the radiation dose to the cancerous cells to preserve healthy surrounding tissue. This is safer both for patients and for radiation therapy staff who are able to remain in the room to monitor and reassure patients during the treatments.”

Treatment options for nonmelanoma skin cancer include several types of surgery, topical treatments, and radiation therapy. The location and extent of the cancer influences the selection of the best treatment options for each patient. Whether in combination with surgery or as a standalone treatment, electronic brachytherapy enables clinicians to administer radiation therapy without the use of a radioactive isotope and in clinical settings where a shielded vault is not needed.

Available for treatment of early stage breast cancer, endometrial cancer, and skin cancer, the Axxent eBx system is also FDA cleared for use in the treatment of surface cancers or conditions where radiation therapy is indicated, including intraoperative radiation therapy (IORT). As a platform technology, the Axxent system is designed to deliver nonradioactive therapy directly to cancer sites with minimal radiation exposure to surrounding healthy tissue. Utilizing a proprietary miniaturized X-ray source and robotic controller, treatment can be performed in minimally shielded therapeutic settings allowing the radiation oncologist and other medical personnel to be present during treatment delivery and minimizing patient anxiety.

The University of Wisconsin Cancer Center Riverview is affiliated with the University of Wisconsin Carbone Cancer Center (Madison, WI, USA). In November 2006 the Riverview center became the first in central Wisconsin to treat patients with helical tomotherapy, the most sophisticated and effective image-guided and intensity-modulated radiation therapy that exists today.

Xoft develops electronic brachytherapy (eBx) systems based upon miniaturized X-ray tube technology for the practice of radiation oncology in virtually any clinical setting, eliminating the need for heavily shielded environments. Xoft provides a point of care model that is patient centric and accessible to a broader spectrum of patients and their physicians. The Axxent treatment platform provides a therapeutic dose of radiation directly to the region at risk with minimal radiation exposure to surrounding healthy tissue and without the complex handling, resource logistics, and costs associated with using radioactive isotopes. Xoft aligns with the Nuclear Regulatory Commission's (NRC; Wahsington DC, USA) directive to seek alternatives for radioactive medical isotopes. Commercially available for treatment of early stage breast cancer, skin cancer, and endometrial and rectal indications, the Axxent electronic brachytherapy system is also cleared for use in the treatment of other cancers or conditions where radiation therapy is indicated.

Related Links:
Xoft
University of Wisconsin Cancer Center Riverview

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56 (391.00646972656): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294724967 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

57 (!!!!! 2813.1008148193): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

58 (!!!!! 2384.9010467529): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

59 (!!!!! 9039.8788452148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

60 (193.11904907227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

61 (!!!!! 2667.1886444092): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (806.09321594238): SELECT fid FROM jos_deeppockets WHERE id=294724967 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294724967 AND published='1' LIMIT 1

63 (!!!!! 1795.0534820557): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

64 (120.16296386719): select jos_twitters.link from jos_twitters where cat=10

65 (46.968460083008): select jos_facebook.link from jos_facebook where cat=10

66 (47.922134399414): select jos_google_plus.link from jos_google_plus where cat=10

67 (40.054321289062): select jos_linkedin.link from jos_linkedin where cat=10

68 (55.074691772461): SELECT fid FROM jos_deeppockets WHERE id=294724967 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294724967 AND published='1' LIMIT 1

69 (61.03515625): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

70 (!!!!! 3852.8442382812): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294724967 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (!!!!! 1111.9842529297): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294724967 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (105.85784912109): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 2156.9728851318): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (288.00964355469): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (446.08116149902): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (234.12704467773): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (189.06593322754): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (175.95291137695): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (!!!!! 1737.8330230713): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294724967 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (69.141387939453): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294724967 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (!!!!! 3826.1413574219): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 4091.0243988037): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (!!!!! 3520.0119018555): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (926.97143554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (63.896179199219): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (55.789947509766): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (383.85391235352): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (626.0871887207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

105 (174.99923706055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

106 (118.01719665527): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294724967 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (!!!!! 1353.9791107178): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294724967 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 7233.8581085205): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

109 (385.04600524902): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

110 (181.19812011719): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294724967 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 3998.9948272705): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294724967 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 5159.854888916): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (!!!!! 5285.0246429443): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (257.96890258789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

115 (188.11225891113): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

116 (!!!!! 1384.0198516846): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

117 (107.0499420166): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

118 (313.04359436035): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

119 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

120 (618.93463134766): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

121 (208.85467529297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

122 (!!!!! 3236.0553741455): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 51647.901535034): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 5010.8432769775): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294724967 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294724967 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 104969.97833252): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (102.04315185547): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (239.13383483887): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (221.01402282715): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (76.055526733398): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (143.05114746094): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (319.00405883789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (44.107437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (!!!!! 1769.0658569336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (!!!!! 1302.95753479): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (!!!!! 2364.8738861084): SELECT name FROM jos_deeppockets WHERE id=213

138 (60.796737670898): SELECT name FROM jos_deeppockets WHERE id=213

139 (!!!!! 1488.9240264893): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (!!!!! 1576.9004821777): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (!!!!! 4549.9801635742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

142 (485.18180847168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

143 (!!!!! 21239.042282104): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 4039.0491485596): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294724967 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (457.0484161377): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294724967 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 2650.0225067139): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (685.9302520752): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (!!!!! 4526.1383056641): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

149 (634.90867614746): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

150 (!!!!! 3979.9213409424): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (!!!!! 1857.0423126221): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

152 (565.0520324707): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

153 (!!!!! 1749.9923706055): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294724967 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294724967 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (52.928924560547): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

155 (247.00164794922): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

156 (!!!!! 2448.0819702148): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 6375.0743865967): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

158 (!!!!! 5481.0047149658): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294724967 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294724967 AND published='1' LIMIT 1

159 (!!!!! 1100.0633239746): select jos_twitters.link from jos_twitters where cat=10

160 (247.00164794922): select jos_facebook.link from jos_facebook where cat=10

161 (49.829483032227): select jos_google_plus.link from jos_google_plus where cat=10

162 (354.05158996582): select jos_linkedin.link from jos_linkedin where cat=10

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