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Electronic Brachytherapy Delivered to Cancer Sites in Minimally Shielded Clinical Settings

By MedImaging staff writers
Posted on 30 Apr 2008

Image: Colored profile x-ray of the left breast of a 65-year-old woman with breast cancer (Photo courtesy of Zephyr / SPL)

A proprietary technology platform has been designed to deliver localized, nonradioactive, isotope-free radiation treatment in minimally shielded clinical settings.

Xoft, Inc. (Sunnyvale, CA, USA) has received expanded clearance from the U.S. Food & Drug Administration (FDA) for the Axxent electronic brachytherapy system. Previously cleared for accelerated treatment of early stage breast cancer, the Axxent System is now cleared for use in the treatment of other cancers or conditions where radiation therapy is indicated.

As a platform technology, the system is designed to address a range of oncologic and non-oncologic indications. Xoft is actively working to extend the use of electronic brachytherapy to endometrial and rectal indications, which are pending FDA clearance.

"The prospect of expanding the use of electronic brachytherapy beyond our breast cancer patients is very exciting,” said Adam Dickler, radiation oncologist at Little Company of Mary Hospital (Chicago, IL, USA). "The ability to deliver electronic X-ray-based therapy directly to the cancer site spares healthy tissue and gives us the ability to provide that therapy in a broader spectrum of clinical settings. This tool has been very well received by our breast cancer patients, and we would expect it deliver similar benefits across a range of cancer treatments.”

Designed to deliver electronic, X-ray-based radiation treatment, the proprietary Axxent treatment platform can be used in virtually any clinical setting under the supervision of a radiation oncologist. The Axxent system is designed to deliver nonradioactive therapy directly to cancer sites with minimal radiation exposure to surrounding healthy tissue. Eliminating the need for heavily shielded environments, it gives radiation oncologists the flexibility to deliver therapy in a broader range of clinical settings. As a result, more patients will have greater access to therapy that is delivered more easily and conveniently.

In its current use for the treatment of early stage breast cancer, the Axxent electronic brachytherapy system also provides the opportunity to reduce the therapy time required from seven weeks (for external radiation therapy) down to five days. As a result, more patients will have greater access to therapy and this may accelerate patient choice of breast-sparing lumpectomy surgery with adjuvant radiation therapy over the alternative of a full mastectomy.

"The expanded clearance for the Axxent Controller is very significant in that it validates that the FDA recognizes electronic brachytherapy is a platform technology that is viable for treatment of conditions outside of the breast,” said Michael Klein, president and CEO of Xoft. "This serves as the foundation for Xoft's expansion into new treatment areas beyond breast cancer and fuels the continued market adoption and expansion of this important technology.”

Xoft is developing leading-edge new technologies for the practice of radiation oncology through electronic brachytherapy, which utilizes proprietary miniaturized X-ray tube technology. The Axxent electronic brachytherapy system, Xoft's first treatment solution, is currently being used in accelerated partial breast irradiation (APBI) for the treatment of early-stage breast cancer. This system provides a therapeutic dose of intracavitary radiation directly to the region at risk without the complex handling and resource logistics necessary when performing brachytherapy using radioactive isotopes.

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63 (107.0499420166): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

64 (581.97975158691): select jos_twitters.link from jos_twitters where cat=10

65 (174.99923706055): select jos_facebook.link from jos_facebook where cat=10

66 (391.96014404297): select jos_google_plus.link from jos_google_plus where cat=10

67 (124.93133544922): select jos_linkedin.link from jos_linkedin where cat=10

68 (!!!!! 1191.8544769287): SELECT fid FROM jos_deeppockets WHERE id=279990000 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=279990000 AND published='1' LIMIT 1

69 (65.803527832031): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

70 (427.9613494873): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=279990000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (488.0428314209): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=279990000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (!!!!! 1827.0015716553): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (67.949295043945): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (37.193298339844): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (!!!!! 2485.0368499756): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (86.784362792969): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (51.021575927734): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=279990000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (30.994415283203): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=279990000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (35.04753112793): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (57.93571472168): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (42.200088500977): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (72.002410888672): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (!!!!! 2167.9401397705): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (71.048736572266): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 1402.8549194336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

105 (84.161758422852): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

106 (68.902969360352): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=279990000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (623.94142150879): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=279990000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 4361.1526489258): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

109 (142.81272888184): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

110 (104.18891906738): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=279990000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (694.99015808105): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=279990000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (691.89071655273): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (441.7896270752): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (81.062316894531): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

115 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

116 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

117 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

118 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

119 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

120 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

121 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

122 (381.9465637207): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 56635.141372681): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 2372.9801177979): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=279990000 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=279990000 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 20409.822463989): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (247.00164794922): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (!!!!! 3082.9906463623): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (127.79235839844): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (95.844268798828): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (56.028366088867): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (495.19538879395): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (66.041946411133): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (60.796737670898): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (47.922134399414): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (868.08204650879): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (602.96058654785): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (200.03318786621): SELECT name FROM jos_deeppockets WHERE id=213

138 (196.21849060059): SELECT name FROM jos_deeppockets WHERE id=213

139 (729.08401489258): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (890.01655578613): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (401.02005004883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

142 (272.03559875488): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

143 (!!!!! 8829.8320770264): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 5101.9191741943): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=279990000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (117.06352233887): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=279990000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (916.0041809082): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (85.115432739258): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (405.07316589355): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

149 (337.12387084961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

150 (!!!!! 5904.9129486084): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (!!!!! 1937.8662109375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

152 (118.01719665527): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

153 (!!!!! 1704.9312591553): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=279990000 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=279990000 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (60.081481933594): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

155 (45.061111450195): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

156 (55.074691772461): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (422.95455932617): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

158 (343.08433532715): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=279990000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=279990000 AND published='1' LIMIT 1

159 (!!!!! 7569.0746307373): select jos_twitters.link from jos_twitters where cat=10

160 (!!!!! 8009.9105834961): select jos_facebook.link from jos_facebook where cat=10

161 (!!!!! 4559.9937438965): select jos_google_plus.link from jos_google_plus where cat=10

162 (!!!!! 7285.1181030273): select jos_linkedin.link from jos_linkedin where cat=10

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