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Use of PET/CT in Radiotherapy Planning for Head and Neck Cancer Provides Excellent Clinical Outcomes

By MedImaging staff writers
Posted on 31 Mar 2008

Using a combination of positron emission tomography (PET) and computed tomography (CT) for radiation therapy treatment planning in head and neck carcinoma patients provides for excellent, local, and regional disease control when compared to CT alone, according to a recent study.

CT has been the standard choice for staging and radiation therapy treatment planning for head and neck squamous cell carcinomas, which account for approximately 5% of malignancies worldwide; but PET has been shown to have advantages over CT and other imaging modalities in detecting primary tumors involving lymph nodes and distant metastatic disease not clearly otherwise identified. PET alone does have several disadvantages, however, such as poor correlation to precise anatomic structures, but these negative impacts are significantly reduced when PET and CT are combined by fusing the separate scans taken on a hybrid scanner.

While it has been proven in several studies that PET/CT imaging is feasible for head and neck radiation therapy planning, very few studies have been done to determine the clinical outcomes. Therefore, researchers in the departments of radiation oncology, radiology, neoplastic and related disorders, and otolaryngology at the Medical College of Wisconsin (Milwaukee, USA) conducted this study to evaluate the clinical outcomes, including overall survival, disease-free survival, and the incidence of recurrence of patients receiving PET/CT-guided radiation therapy and the correlation of the clinical outcomes to the maximum standard uptake value obtained on the PET scan.

Between December 2002 and August 2006, 42 patients with a median age of 55, who were diagnosed with head and neck squamous cell carcinoma, were given PET/CT imaging as part of their radiation therapy planning. All patients were observed for at least six months following their treatment, with a mean follow-up time of 32 months.

Overall survival of the 42 study patients was 82.8% at two years and 74.1% at three years, superior to the survival rate that was found in a Radiation Therapy Oncology Group study in which patients received standard fractionation or accelerated fractionation with concomitant boost. That study was the largest randomized trial of radiation therapy in locally advanced head and neck cancer.

Disease-free survival for the 42 study patients was 71% and 66.9% at two and three years respectively. The cumulative incidence of recurrence was 18.7%. The study also found that standard uptake value is not a good predictor of local recurrence, and that dose escalation based on standard uptake value is unlikely to be a effective treatment strategy.

"PET/CT provides a higher level of confidence that we are not missing tumors as we attempt to lessen treatment side effects by delivering radiation therapy that tightly conforms in three dimensions to a given tumor volume,” said Christopher Schultz, M.D., professor of radiation oncology at the Medical College of Wisconsin. "Most importantly the PET/CT-guided conformal radiotherapy was clearly no worse, and based on our early results may in fact lead to superior clinical outcomes as compared to CT only planned radiotherapy.”

The study was published in the March 1, 2008, issue of the International Journal for Radiation Oncology*Biology*Physics.

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62 (!!!!! 3361.9403839111): SELECT fid FROM jos_deeppockets WHERE id=276660000 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=276660000 AND published='1' LIMIT 1

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64 (!!!!! 3887.8917694092): select jos_twitters.link from jos_twitters where cat=10

65 (128.98445129395): select jos_facebook.link from jos_facebook where cat=10

66 (634.90867614746): select jos_google_plus.link from jos_google_plus where cat=10

67 (51.975250244141): select jos_linkedin.link from jos_linkedin where cat=10

68 (458.95576477051): SELECT fid FROM jos_deeppockets WHERE id=276660000 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=276660000 AND published='1' LIMIT 1

69 (42.915344238281): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

70 (!!!!! 1226.9020080566): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=276660000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (360.01205444336): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=276660000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (307.08312988281): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 6309.986114502): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (118.97087097168): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (!!!!! 4399.0612030029): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (125.16975402832): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (966.07208251953): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (68.902969360352): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (48.87580871582): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (532.15026855469): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=276660000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (52.928924560547): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=276660000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (56.982040405273): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 1175.1651763916): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (949.85961914062): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (!!!!! 5743.0267333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (!!!!! 2823.1143951416): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (459.90943908691): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (92.029571533203): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (60.081481933594): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (346.89903259277): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (197.8874206543): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (258.20732116699): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 6125.9269714355): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

105 (439.88227844238): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

106 (!!!!! 1168.0126190186): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=276660000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (!!!!! 1686.8114471436): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=276660000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 3343.1053161621): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

109 (292.06275939941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

110 (615.11993408203): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=276660000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 1366.138458252): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=276660000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 1629.114151001): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (!!!!! 1237.8692626953): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (!!!!! 2058.9828491211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

115 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

116 (!!!!! 1319.8852539062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

117 (!!!!! 1214.9810791016): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

118 (!!!!! 1831.0546875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

119 (969.88677978516): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

120 (!!!!! 5667.9248809814): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

121 (!!!!! 1128.9119720459): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

122 (!!!!! 1875.1621246338): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 88202.953338623): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 3685.9512329102): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=276660000 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=276660000 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 1350.1644134521): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (!!!!! 1498.9376068115): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (!!!!! 3517.8661346436): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (73.909759521484): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (!!!!! 1278.8772583008): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (919.10362243652): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (482.08236694336): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (59.843063354492): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (849.96223449707): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (365.01884460449): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (!!!!! 3730.0586700439): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (623.94142150879): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (362.15782165527): SELECT name FROM jos_deeppockets WHERE id=213

138 (44.107437133789): SELECT name FROM jos_deeppockets WHERE id=213

139 (939.13078308105): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (905.03692626953): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (!!!!! 4545.9270477295): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

142 (481.12869262695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

143 (!!!!! 29341.93611145): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 4779.1004180908): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=276660000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (424.86190795898): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=276660000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 1107.931137085): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (556.94580078125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

149 (98.943710327148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

150 (!!!!! 3643.9895629883): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (!!!!! 3867.8646087646): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

152 (805.13954162598): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

153 (77.009201049805): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=276660000 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=276660000 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (45.061111450195): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

155 (124.93133544922): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

156 (273.9429473877): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (588.89389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

158 (272.98927307129): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=276660000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=276660000 AND published='1' LIMIT 1

159 (!!!!! 1335.8592987061): select jos_twitters.link from jos_twitters where cat=10

160 (!!!!! 1298.9044189453): select jos_facebook.link from jos_facebook where cat=10

161 (87.02278137207): select jos_google_plus.link from jos_google_plus where cat=10

162 (46.014785766602): select jos_linkedin.link from jos_linkedin where cat=10

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