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Radiomics Model Predicts Heart Attacks From CT Images

By MedImaging International staff writers
Posted on 15 Feb 2023

Image: Radiomics allows researchers to extract measurable data from CT images (Photo courtesy of Pexels)

Coronary artery disease is commonly identified with fatty deposits of plaque that accumulate within artery walls. Large, lipid-rich plaques are especially prone to rupturing which ultimately leads to most heart attacks. Identifying which plaques may rupture in the future has so far been difficult. To address this issue, researchers are now using an approach called radiomics that can generate quantitative data from CT scans in order to detect underlying characteristics that are not normally visible in the images. This data can be used to predict future cardiac events such as heart attacks.

Researchers at the Medical School of Nanjing University (Nanjing, China) have created a radiomics model that utilizes data from coronary CT angiography scans to evaluate plaque vulnerability. The model was developed using data from 299 patients and then tested in 708 patients suspected of having coronary artery disease. The model enabled the researchers to identify plaques that carried a higher risk of major adverse cardiac events such as heart attacks. Furthermore, a high radiomic signature was found to be independently associated with these events over a median three-year follow-up.

According to the researchers, the radiomic signature can be easily added to clinical practice. It could assess plaques that are possibly vulnerable and aid in distinguishing high-risk patients in the clinic. The researchers next intend to develop a radiomics model from different scanner types and vendors and also plan to conduct a larger, multicenter study of 10,000 patients.

"Radiomics provided a more accurate approach to detect vulnerable plaques compared to conventional coronary CT angiography anatomical parameters," said study co-lead author Long Jiang Zhang, M.D., Ph.D., from the Department of Radiology at Jinling Hospital, Medical School of Nanjing University in Nanjing. "If the radiomics analysis is embedded into the routine CT angiography workstation, it can automatically identify vulnerable plaques for clinician review. Thus, radiomics may significantly improve the accuracy and precision of high-risk plaque detection in routine clinical practice."

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71 (181.91337585449): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796251 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (43.153762817383): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 2275.9437561035): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (!!!!! 5325.0789642334): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (!!!!! 9724.8554229736): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (!!!!! 7928.8482666016): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (!!!!! 2151.9660949707): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (529.05082702637): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (503.0632019043): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (307.08312988281): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (463.00888061523): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (530.95817565918): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (222.92137145996): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (97.036361694336): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (247.95532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (!!!!! 5074.0242004395): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (!!!!! 1376.1520385742): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796251 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (!!!!! 1291.9902801514): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796251 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (!!!!! 1005.1727294922): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (32.186508178711): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

105 (!!!!! 1312.0174407959): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

106 (51.021575927734): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796251 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (498.05641174316): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796251 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 1485.1093292236): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

109 (563.8599395752): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

110 (336.88545227051): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796251 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (581.97975158691): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796251 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (566.95938110352): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (424.14665222168): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (75.817108154297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

115 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

116 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

117 (38.14697265625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

118 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

119 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

120 (248.90899658203): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 80561.16104126): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

123 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

124 (370.97930908203): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796251 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796251 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 1081821.9184875): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (!!!!! 1407.1464538574): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (!!!!! 1398.0865478516): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (190.97328186035): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (236.03439331055): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (138.0443572998): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (118.01719665527): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (144.00482177734): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (399.11270141602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (368.83354187012): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (537.87231445312): SELECT name FROM jos_deeppockets WHERE id=215

136 (39.100646972656): SELECT name FROM jos_deeppockets WHERE id=215

137 (591.03965759277): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (508.78524780273): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (174.99923706055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

140 (256.06155395508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

141 (!!!!! 14343.023300171): TRUNCATE TABLE jos_trademed_module

142 (72.002410888672): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796251 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (49.114227294922): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796251 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (419.13986206055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

147 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

148 (!!!!! 1770.01953125): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (499.01008605957): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

150 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

151 (41.007995605469): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796251 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796251 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (34.093856811523): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

153 (28.848648071289): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

154 (79.870223999023): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (122.0703125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

156 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796251 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796251 AND published='1' LIMIT 1

157 (76.055526733398): select jos_twitters.link from jos_twitters where cat=10

158 (30.994415283203): select jos_facebook.link from jos_facebook where cat=10

159 (30.040740966797): select jos_google_plus.link from jos_google_plus where cat=10

160 (27.894973754883): select jos_linkedin.link from jos_linkedin where cat=10

161 (270.84350585938): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 1111.9842529297): insert into jos_banners_delta values (14615,'2025-04-30 18:39:32','3.144.104.136','view'),(14202,'2025-04-30 18:39:32','3.144.104.136','view'),(14203,'2025-04-30 18:39:32','3.144.104.136','view')

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