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New Research Refutes the Concept of Iodine Allergies

By MedImaging International staff writers
Posted on 04 Oct 2021
Image: A new study concludes Iodine allergy is a myth (Photo courtesy of iStockPhoto)
Image: A new study concludes Iodine allergy is a myth (Photo courtesy of iStockPhoto)

A new study concludes that there is no impediment to administering iodine-containing contrast agents before imaging, as there are no verified, documented cases of allergic reactions to iodine.

Researchers at First Databank (San Francisco, CA, USA), Stanson Health (Charlotte, NC, USA), and the Mayo Clinic (Rochester, MN, USA) conducted a literature review to evaluate current evidence regarding iodine allergy and iodine-containing drugs. In all, of 435 articles considered potentially appropriate for full review (plus an additional 12 articles included on the basis of references from the eligible articles), 113 could not be obtained. After exclusion of 353 articles that did not meet all inclusion criteria, the remaining 81 articles were included in the review.

The results indicated iodine has not been shown to be the allergen responsible for allergic reactions to iodinated contrast media, amiodarone, povidone-iodine, and other iodine-containing compounds, and that therefore there is a lack of evidence supporting cross-reactivity between iodine-containing compounds in those defined as iodine-allergic individuals. The study was published in the May 2021 issue of the American Journal of Health-System Pharmacy.

“We could find no documented cases from more than 70 years of research where iodine itself was responsible for patient reactions,” said lead author Nicole Wulf, PharmD, of FDB. “While these patients likely had reactions to the contrast media, iodine was most likely not responsible, nor did most of these reactions meet the definition of an allergic reaction, which requires an immune-mediated reaction such as antibody release and symptoms such as rash, swollen tongue or face, or even difficulty breathing.”

“Another unfortunate consequence of a patient's self-identified iodine allergy is that it could result in a care delay or a patient receiving unnecessary steroids before an imaging test, which could cause harm,” said senior author Joan Kapusnik-Uner, PharmD . “Healthcare providers who still ask patients about iodine or seafood allergies before an imaging study should reassess these protocols and implement a safety screen that is evidence-based. The bottom line is contrast agents help save lives, and should be used when clinically indicated and safe to do so.”

Iodine is an essential trace element for life, used as a constituent of the thyroid hormones thyroxine (T4) and triiodothyronine (T3). As humans cannot produce it, it must be consumed. As iodine levels in seafood are higher than in non-seafood items, a common myth is that seafood "allergy" results from the iodine, while in fact it an allergic reaction to the muscle protein tropomyosin. In fact, over 85% of patients with reported seafood allergies will not have an adverse reaction to iodinated contrast agents.

Related Links:
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Stanson Health
Mayo Clinic


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		LIMIT 1
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(53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
50
(87.976455688477): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
51
(56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
52
(343.79959106445): SELECT name FROM jos_deeppockets WHERE id=294789975 LIMIT 1
53
(283.95652770996): SELECT name FROM jos_deeppockets_archive WHERE id=294789975 LIMIT 1
54
(58.174133300781): SELECT a.*
 FROM jos_components AS a
 WHERE ( a.admin_menu_link = 'option=com_syndicate' OR a.admin_menu_link = 'option=com_syndicate&hidemainmenu=1' )
 AND a.option = 'com_syndicate'
55
(52.928924560547): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294789975
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
56
(602.00691223145): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294789975
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
57
(!!!!! 1127.0046234131): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
58
(56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
59
(85.115432739258): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
60
(47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
61
(88.930130004883): select cover from jos_number
where journalid in (5) and cover is not null
order by left(issue,2)+right(issue,2)*12 desc limit 1
62
(511.88468933105): SELECT fid FROM jos_deeppockets WHERE id=294789975 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294789975 AND published='1'  LIMIT 1
63
(427.0076751709): SELECT id,name,sponsor_text
                    FROM jos_deeppockets dp
					left outer join jos_channel_sponsor cs
					on dp.id=cs.fid
                    WHERE cat=10
                    AND TYPE='file_folder'
                    AND published=1
                    AND id=215
                    ORDER BY `ordering`
64
(47.922134399414): select jos_twitters.link from jos_twitters where cat=10
65
(28.848648071289): select jos_facebook.link from jos_facebook where cat=10
66
(30.040740966797): select jos_google_plus.link from jos_google_plus where cat=10
67
(30.040740966797): select jos_linkedin.link from jos_linkedin where cat=10
68
(31.948089599609): SELECT fid FROM jos_deeppockets WHERE id=294789975 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294789975 AND published='1'  LIMIT 1
69
(30.994415283203): SELECT id,name,sponsor_text
                    FROM jos_deeppockets dp
					left outer join jos_channel_sponsor cs
					on dp.id=cs.fid
                    WHERE cat=10
                    AND TYPE='file_folder'
                    AND published=1
                    AND id=215
                    ORDER BY `ordering`
70
(296.83113098145): SELECT fid FROM jos_deeppockets
								WHERE cat=10
								AND id=294789975
								AND (type='deeppockets_item' OR type='deeppockets_item_link') 
								AND published='1' 
								LIMIT 1
71
(218.86825561523): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294789975 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
72
(36.954879760742): SELECT id,name,title
 FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
			AND id != 294743300
			AND id != 294743301
			AND id != 294743302
			AND id != 294743303
			AND id != 294743304
			AND id != 294743305
			AND id != 294743306
			AND id != 294743307
			AND id != 294743308
			AND id != 294743309
			AND id != 294743310
			AND metakey != 'aacc'
		ORDER BY `ordering`
73
(136.13700866699): SELECT show_live FROM jos_com_show_setting LIMIT 1
74
(32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1
75
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
76
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
77
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
78
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
79
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
80
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
81
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
82
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
83
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
84
(27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1
85
(26.226043701172): SELECT show_live FROM jos_com_show_setting LIMIT 1
86
(27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1
87
(46.014785766602): SELECT fid FROM jos_deeppockets
								WHERE cat=10
								AND id=294789975
								AND (type='deeppockets_item' OR type='deeppockets_item_link') 
								AND published='1' 
								LIMIT 1
88
(35.04753112793): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294789975 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
89
(34.809112548828): SELECT id,name,title
 FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
			AND id != 294743300
			AND id != 294743301
			AND id != 294743302
			AND id != 294743303
			AND id != 294743304
			AND id != 294743305
			AND id != 294743306
			AND id != 294743307
			AND id != 294743308
			AND id != 294743309
			AND id != 294743310
			AND metakey != 'aacc'
		ORDER BY `ordering`
90
(56.028366088867): SELECT show_live FROM jos_com_show_setting LIMIT 1
91
(51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1
92
(30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1
93
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
94
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
95
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
96
(37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1
97
(29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1
98
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
99
(32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1
100
(39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1
101
(30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1
102
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
103
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
104
(78.916549682617): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
105
(43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
106
(54.836273193359): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294789975
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
107
(49.114227294922): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294789975
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
108
(73.19450378418): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
109
(42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
110
(47.922134399414): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							
							AND dp.id=294789975
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
111
(463.00888061523): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								
								AND dp.id=294789975
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
112
(540.97175598145): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as ex
							ON ex.id = dp.author
							LEFT JOIN jos_deeppockets as dp2
							ON dp2.id = dp.fid
							WHERE dp.author != 0
							AND dp.cat = 10
							AND dp.published = 1
							AND (
								(dp.fid = 294743300)
								OR (dp.fid = 294743301)
								OR (dp.fid = 294743302)
								OR (dp.fid = 294743303)
								OR (dp.fid = 294743304)
								OR (dp.fid = 294743305)
								OR (dp.fid = 294743306)
								OR (dp.fid = 294743307)
								OR (dp.fid = 294743308)
								OR (dp.fid = 294743309)
								OR (dp.fid = 294743310)
								)
							ORDER BY RAND()
							LIMIT 1
113
(401.97372436523): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as ex
							ON ex.id = dp.author
							LEFT JOIN jos_deeppockets as dp2
							ON dp2.id = dp.fid
							WHERE dp.author != 0
							AND dp.cat = 10
							AND dp.published = 1
							AND (
								(dp.fid = 294743300)
								OR (dp.fid = 294743301)
								OR (dp.fid = 294743302)
								OR (dp.fid = 294743303)
								OR (dp.fid = 294743304)
								OR (dp.fid = 294743305)
								OR (dp.fid = 294743306)
								OR (dp.fid = 294743307)
								OR (dp.fid = 294743308)
								OR (dp.fid = 294743309)
								OR (dp.fid = 294743310)
								)
							ORDER BY RAND()
							LIMIT 1
114
(72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
115
(56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
116
(92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
117
(95.844268798828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
118
(82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
119
(47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
120
(334.9781036377): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`
121
(!!!!! 22720.098495483): SELECT
				*
			FROM
				jos_deeppockets
			WHERE
				jos_deeppockets.cat = 10
			AND
				jos_deeppockets.type = 'deeppockets_item'
			AND
				jos_deeppockets.published = 1
			AND
				jos_deeppockets.created + INTERVAL 14 DAY >= NOW()
			ORDER BY
				jos_deeppockets.hits DESC
			LIMIT
				7
122
(81.777572631836): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
123
(79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
124
(519.99092102051): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294789975 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294789975 AND type='deeppockets_item' AND published='1'  LIMIT 1
125
(!!!!! 609894.0372467): (
				SELECT
					dp.id,
					dp.name,
					dp.title,
					dp.video,
					dp.video_source,
					dp.created

				FROM
					jos_deeppockets AS dp

				WHERE
					dp.video != ''
				AND
					dp.video_source != ''
				AND
					dp.cat = 10
				AND
					dp.published = 1
				AND
					dp.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			UNION
			(
				SELECT
					dpa.id,
					dpa.name,
					dpa.title,
					dpa.video,
					dpa.video_source,
					dpa.created

				FROM
					jos_deeppockets_archive AS dpa

				WHERE
					dpa.video != ''
				AND
					dpa.video_source != ''
				AND
					dpa.cat = 10
				AND
					dpa.published = 1
				AND
					dpa.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			ORDER BY
				created DESC

			LIMIT
				3
126
(74.148178100586): (
				SELECT
					dp.id,
					dp.name,
					dp.title,
					dp.video,
					dp.video_source,
					dp.created

				FROM
					jos_deeppockets AS dp

				WHERE
					dp.video != ''
				AND
					dp.video_source != ''
				AND
					dp.cat = 10
				AND
					dp.published = 1
				AND
					dp.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			UNION
			(
				SELECT
					dpa.id,
					dpa.name,
					dpa.title,
					dpa.video,
					dpa.video_source,
					dpa.created

				FROM
					jos_deeppockets_archive AS dpa

				WHERE
					dpa.video != ''
				AND
					dpa.video_source != ''
				AND
					dpa.cat = 10
				AND
					dpa.published = 1
				AND
					dpa.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			ORDER BY
				created DESC

			LIMIT
				3
127
(63.180923461914): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800513

			LIMIT 1
128
(40.054321289062): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800513

			LIMIT 1
129
(79.154968261719): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800359

			LIMIT 1
130
(52.928924560547): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800359

			LIMIT 1
131
(41.007995605469): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800361

			LIMIT 1
132
(38.862228393555): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800361

			LIMIT 1
133
(691.17546081543): SELECT *
                            FROM jos_deeppockets
                            WHERE 1=1 
                              AND id=294789975
                              AND (type='deeppockets_item' OR type='deeppockets_item_link')
                              AND published='1'
                            LIMIT 1
134
(522.13668823242): SELECT *
                            FROM jos_deeppockets_archive
                            WHERE 1=1 
                              AND id=294789975
                              AND (type='deeppockets_item' OR type='deeppockets_item_link')
                              AND published='1'
                            LIMIT 1
135
(313.04359436035): SELECT name FROM jos_deeppockets WHERE id=215
136
(45.061111450195): SELECT name FROM jos_deeppockets WHERE id=215
137
(612.97416687012): SELECT *,
    DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
    DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
    FROM jos_events
    WHERE state=1
    AND publish_up > NOW()
    and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) 
    ORDER BY publish_up ASC LIMIT 3
138
(526.18980407715): SELECT *,
    DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
    DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
    FROM jos_events
    WHERE state=1
    AND publish_up > NOW()
    and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) 
    ORDER BY publish_up ASC LIMIT 3
139
(88.930130004883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
140
(72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
141
(!!!!! 8364.9158477783): TRUNCATE TABLE jos_trademed_module
142
(83.92333984375): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294789975
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
143
(55.074691772461): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294789975
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
144
(771.99935913086): SELECT *
   FROM jos_deeppockets
   WHERE 1=1 
   AND id=294789975
   AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
145
(66.041946411133): SELECT *
   FROM jos_deeppockets
   WHERE 1=1 
   AND id=294789975
   AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
146
(59.843063354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
147
(46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
148
(!!!!! 1028.0609130859): SELECT jos_item.*
						FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
						WHERE 1=1
						AND (jos_item.imgMini<>'')
						AND jos_item.type='L'
						AND jos_item.numberID= (
									 SELECT jos_number.id
									 FROM jos_number
									 WHERE jos_number.journalID IN (10)
						
									and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
									 ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
									 LIMIT 0,1
									 )
						ORDER BY RAND() DESC LIMIT 6
149
(54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
150
(38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
151
(41.961669921875): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294789975 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294789975 AND type='deeppockets_item' AND published='1'  LIMIT 1
152
(36.001205444336): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=215 or channel_id is null)
153
(36.001205444336): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=215 or channel_id is null)
154
(41.007995605469): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1
155
(66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
156
(46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789975 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789975 AND published='1'
		LIMIT 1
157
(35.04753112793): select jos_twitters.link from jos_twitters where cat=10
158
(30.040740966797): select jos_facebook.link from jos_facebook where cat=10
159
(29.802322387695): select jos_google_plus.link from jos_google_plus where cat=10
160
(44.822692871094): select jos_linkedin.link from jos_linkedin where cat=10
161
(275.85029602051): update jos_bannersmanager_banner
			set impmade=impmade+1
			where id in(14615,14202,14203)
162
(!!!!! 1343.9655303955): insert into jos_banners_delta values (14615,'2025-06-18 11:40:46','216.73.216.120','view'),(14202,'2025-06-18 11:40:46','216.73.216.120','view'),(14203,'2025-06-18 11:40:46','216.73.216.120','view')