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Next Generation Radio-Wave Breast Scanning System Aims to Transform Breast Cancer Detection Landscape

By MedImaging International staff writers
Posted on 08 Aug 2021

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The next generation model of a disruptive breast scanning system currently under development promises to transform the landscape of breast cancer detection.

Micrima Limited (Bristol, England) has received funding that will enable the next stage of development and commercialization of its MARIA system, a new breast imaging modality based on radio wave technology. MARIA offers new diagnostic information in dense tissue whilst requiring no breast compression or ionizing radiation exposure to the patient. This makes the system safe and comfortable for the patient and hopefully, an alternative to mammography in the future.

The array consists of 60 radio frequency antennae that surround the breast. They are configured to operate over a wide range of frequencies. Each antenna transmits and the other 59 record the signal back from the breast tissue which allows MARIA to build up a 3D map of tissue variation throughout the breast. The system is measuring signals that travel through the breast, any attenuation in this signal as well as any scatter back of the signal. The scanning process takes less than five minutes. The data is then reconstructed before being presented to the clinician as a 3D volume. In clinical trials to date MARIA has proven to locate regions that correspond to invasive breast cancer as shown by biopsy and histology.

The company now hopes to launch the 7th generation model of the MARIA radio-wave breast scanning system later this year. The latest iteration will still offer a safe system - no ionizing radiation, a comfortable system - no breast compression and a system that in clinical trials in diagnostic clinics has proven effective at accurately identifying cancer. The system has proven to be better than the gold standard in dense tissue. The new model will also offer new functionality in density score as well as improvement in accuracy and ergonomics.

Micrima, which has developed the MARIA imaging system to improve early diagnosis of breast cancer, has reached a significant development milestone with initial sales of its novel breast imaging technology. The company is now set to set to embark on a full commercial launch with distribution already established in Germany, Austria and Switzerland through an agreement with Hologic, Inc.
“This investment will allow us to move the company into the next phase with a system that has a place in a clinical workflow and more exciting functionality to come as soon as clinical data collection can recommence,” said Nick Randall, Chairman of Micrima.

“I first became aware of Micrima some four years ago and it has been really interesting to see them moving forward and overcoming their technical challenges with the development of their latest device,” added Adrian Waller, CEO of Micrima. “This latest round of funding allows us to take the new system and work on automatically classifying findings using the rich data set that it produces, which has every opportunity to transform the landscape of breast cancer detection.”

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69 (169.03877258301): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=215 ORDER BY `ordering`

70 (!!!!! 2676.0101318359): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294789200 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (498.05641174316): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294789200 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (!!!!! 33291.101455688): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 3635.8833312988): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (555.03845214844): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (77.009201049805): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (277.04238891602): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (!!!!! 2713.9186859131): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (308.03680419922): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (401.02005004883): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (559.80682373047): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (146.15058898926): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (!!!!! 2219.9153900146): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (321.86508178711): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (478.98292541504): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (61.988830566406): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294789200 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (37.908554077148): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294789200 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (41.007995605469): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (76.055526733398): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (197.8874206543): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (125.88500976562): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (790.83442687988): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (98.943710327148): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (535.01129150391): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (775.81405639648): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

105 (277.04238891602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

106 (!!!!! 1474.142074585): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294789200 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (!!!!! 3074.1691589355): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294789200 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (926.97143554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

109 (488.9965057373): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

110 (714.06364440918): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294789200 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (461.10153198242): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294789200 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 1064.0621185303): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (!!!!! 3355.9799194336): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (118.01719665527): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

115 (74.863433837891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

116 (92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

117 (74.863433837891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

118 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

119 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

120 (432.96813964844): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 44500.112533569): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (119.92454528809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

123 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

124 (625.8487701416): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294789200 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294789200 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 569484.94911194): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (154.01840209961): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (412.94097900391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (66.995620727539): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (344.03800964355): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (56.028366088867): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (286.10229492188): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (51.975250244141): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (576.01928710938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (445.84274291992): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (264.88304138184): SELECT name FROM jos_deeppockets WHERE id=215

136 (54.121017456055): SELECT name FROM jos_deeppockets WHERE id=215

137 (666.14151000977): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (568.86672973633): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

140 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

141 (!!!!! 11567.115783691): TRUNCATE TABLE jos_trademed_module

142 (128.98445129395): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294789200 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (87.02278137207): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294789200 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (566.95938110352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (120.87821960449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

147 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

148 (!!!!! 1487.9703521729): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (121.8318939209): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

150 (75.817108154297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

151 (95.129013061523): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294789200 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294789200 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (54.836273193359): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

153 (46.014785766602): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

154 (52.928924560547): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

156 (59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294789200 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294789200 AND published='1' LIMIT 1

157 (159.02519226074): select jos_twitters.link from jos_twitters where cat=10

158 (31.948089599609): select jos_facebook.link from jos_facebook where cat=10

159 (29.087066650391): select jos_google_plus.link from jos_google_plus where cat=10

160 (29.087066650391): select jos_linkedin.link from jos_linkedin where cat=10

161 (304.9373626709): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 2015.1138305664): insert into jos_banners_delta values (14615,'2025-06-18 10:48:08','216.73.216.120','view'),(14202,'2025-06-18 10:48:08','216.73.216.120','view'),(14203,'2025-06-18 10:48:08','216.73.216.120','view')

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