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AI Algorithm Automates Cystic Fibrosis CT Scan Analysis

By MedImaging International staff writers
Posted on 06 Apr 2021
Image: Original CT scan (L) and Pragma-AI overlay heat map (R) in the lungs of a CF patient and healthy control (Photo courtesy of Thirona)
Image: Original CT scan (L) and Pragma-AI overlay heat map (R) in the lungs of a CF patient and healthy control (Photo courtesy of Thirona)
A new artificial intelligence (AI) algorithm can analyze CT scans of cystic fibrosis (CF) patients in several seconds, without human interference.

The Thirona (Nijmegen, The Netherlands) Pragma-AI is designed to automatically identify lung abnormalities related to CF, such as collapsed lung tissue and abnormal airways. Sensitive, objective information on the pattern and extent of CF lung disease is immediately available, helping clinicians monitor disease progression and supporting clinical treatment planning. Pragma-AI is part of the company’s LungQ quantification software package, which precisely detects emphysematous regions in the lungs, air-trapping, airway morphology, and fissure completeness.

“Artificial intelligence algorithms make medical image analysis easier, more accurate and more effective; but it is hard work. Developing an algorithm that works as well as, and sometimes even better than a clinician, takes time,” said Eva van Rikxoort, Managing Director of Thirona. “The algorithm will be able to quickly and accurately detect bronchiectasis and mucous quantifications in very young patients with CF, making personalized treatment easier.”

“These developments pave the way for using the PRAGMA method in both clinical trials and clinical care. It allows for large scale investigation of CF lung disease in both research studies and clinical trials. This is a crucial component in the evaluation of new expensive treatment options for patients suffering from CF,” said Professor Harm Tiddens, MD, of Erasmus Medical Center (Rotterdam, The Netherlands). “CF patient registries, collecting information on the health status of CF patients, have already shown interest in the PRAGMA-AI method.”

CF is an autosomal recessive genetic disorder that affects mainly the lungs, but also the pancreas, liver, and intestine. It is characterized by abnormal transport of chloride and sodium across an epithelium, leading to thick, viscous secretions. The name refers to the characteristic scarring (fibrosis) and cyst formation within the pancreas, first recognized in the 1930’s. Difficulty breathing is the most serious symptom, resulting from frequent lung infections that are usually treated with antibiotics and other medications.

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(159.02519226074): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
51
(113.01040649414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
52
(427.9613494873): SELECT name FROM jos_deeppockets WHERE id=294787779 LIMIT 1
53
(370.02563476562): SELECT name FROM jos_deeppockets_archive WHERE id=294787779 LIMIT 1
54
(281.09550476074): SELECT a.*
 FROM jos_components AS a
 WHERE ( a.admin_menu_link = 'option=com_syndicate' OR a.admin_menu_link = 'option=com_syndicate&hidemainmenu=1' )
 AND a.option = 'com_syndicate'
55
(77.962875366211): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294787779
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
56
(597.00012207031): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294787779
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
57
(!!!!! 1746.1776733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
58
(102.99682617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
59
(146.15058898926): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
60
(80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
61
(111.81831359863): select cover from jos_number
where journalid in (5) and cover is not null
order by left(issue,2)+right(issue,2)*12 desc limit 1
62
(571.01249694824): SELECT fid FROM jos_deeppockets WHERE id=294787779 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294787779 AND published='1'  LIMIT 1
63
(607.96737670898): SELECT id,name,sponsor_text
                    FROM jos_deeppockets dp
					left outer join jos_channel_sponsor cs
					on dp.id=cs.fid
                    WHERE cat=10
                    AND TYPE='file_folder'
                    AND published=1
                    AND id=215
                    ORDER BY `ordering`
64
(47.922134399414): select jos_twitters.link from jos_twitters where cat=10
65
(30.040740966797): select jos_facebook.link from jos_facebook where cat=10
66
(41.007995605469): select jos_google_plus.link from jos_google_plus where cat=10
67
(31.948089599609): select jos_linkedin.link from jos_linkedin where cat=10
68
(39.100646972656): SELECT fid FROM jos_deeppockets WHERE id=294787779 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294787779 AND published='1'  LIMIT 1
69
(50.067901611328): SELECT id,name,sponsor_text
                    FROM jos_deeppockets dp
					left outer join jos_channel_sponsor cs
					on dp.id=cs.fid
                    WHERE cat=10
                    AND TYPE='file_folder'
                    AND published=1
                    AND id=215
                    ORDER BY `ordering`
70
(205.03997802734): SELECT fid FROM jos_deeppockets
								WHERE cat=10
								AND id=294787779
								AND (type='deeppockets_item' OR type='deeppockets_item_link') 
								AND published='1' 
								LIMIT 1
71
(185.96649169922): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294787779 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
72
(42.915344238281): SELECT id,name,title
 FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
			AND id != 294743300
			AND id != 294743301
			AND id != 294743302
			AND id != 294743303
			AND id != 294743304
			AND id != 294743305
			AND id != 294743306
			AND id != 294743307
			AND id != 294743308
			AND id != 294743309
			AND id != 294743310
			AND metakey != 'aacc'
		ORDER BY `ordering`
73
(60.081481933594): SELECT show_live FROM jos_com_show_setting LIMIT 1
74
(31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1
75
(35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1
76
(37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1
77
(41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1
78
(33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1
79
(29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1
80
(28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1
81
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
82
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
83
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
84
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
85
(36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1
86
(33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1
87
(45.061111450195): SELECT fid FROM jos_deeppockets
								WHERE cat=10
								AND id=294787779
								AND (type='deeppockets_item' OR type='deeppockets_item_link') 
								AND published='1' 
								LIMIT 1
88
(30.040740966797): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294787779 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
89
(67.949295043945): SELECT id,name,title
 FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
			AND id != 294743300
			AND id != 294743301
			AND id != 294743302
			AND id != 294743303
			AND id != 294743304
			AND id != 294743305
			AND id != 294743306
			AND id != 294743307
			AND id != 294743308
			AND id != 294743309
			AND id != 294743310
			AND metakey != 'aacc'
		ORDER BY `ordering`
90
(66.995620727539): SELECT show_live FROM jos_com_show_setting LIMIT 1
91
(56.028366088867): SELECT show_live FROM jos_com_show_setting LIMIT 1
92
(30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1
93
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
94
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
95
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
96
(35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1
97
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
98
(37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1
99
(28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1
100
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
101
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
102
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
103
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
104
(82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
105
(43.153762817383): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
106
(83.92333984375): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294787779
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
107
(70.095062255859): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294787779
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
108
(153.0647277832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
109
(66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
110
(70.810317993164): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							
							AND dp.id=294787779
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
111
(661.13471984863): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								
								AND dp.id=294787779
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
112
(539.06440734863): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as ex
							ON ex.id = dp.author
							LEFT JOIN jos_deeppockets as dp2
							ON dp2.id = dp.fid
							WHERE dp.author != 0
							AND dp.cat = 10
							AND dp.published = 1
							AND (
								(dp.fid = 294743300)
								OR (dp.fid = 294743301)
								OR (dp.fid = 294743302)
								OR (dp.fid = 294743303)
								OR (dp.fid = 294743304)
								OR (dp.fid = 294743305)
								OR (dp.fid = 294743306)
								OR (dp.fid = 294743307)
								OR (dp.fid = 294743308)
								OR (dp.fid = 294743309)
								OR (dp.fid = 294743310)
								)
							ORDER BY RAND()
							LIMIT 1
113
(310.89782714844): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as ex
							ON ex.id = dp.author
							LEFT JOIN jos_deeppockets as dp2
							ON dp2.id = dp.fid
							WHERE dp.author != 0
							AND dp.cat = 10
							AND dp.published = 1
							AND (
								(dp.fid = 294743300)
								OR (dp.fid = 294743301)
								OR (dp.fid = 294743302)
								OR (dp.fid = 294743303)
								OR (dp.fid = 294743304)
								OR (dp.fid = 294743305)
								OR (dp.fid = 294743306)
								OR (dp.fid = 294743307)
								OR (dp.fid = 294743308)
								OR (dp.fid = 294743309)
								OR (dp.fid = 294743310)
								)
							ORDER BY RAND()
							LIMIT 1
114
(119.92454528809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
115
(72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
116
(96.08268737793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
117
(58.174133300781): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
118
(67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
119
(40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
120
(252.96211242676): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`
121
(!!!!! 19838.094711304): SELECT
				*
			FROM
				jos_deeppockets
			WHERE
				jos_deeppockets.cat = 10
			AND
				jos_deeppockets.type = 'deeppockets_item'
			AND
				jos_deeppockets.published = 1
			AND
				jos_deeppockets.created + INTERVAL 14 DAY >= NOW()
			ORDER BY
				jos_deeppockets.hits DESC
			LIMIT
				7
122
(111.10305786133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
123
(51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
124
(351.1905670166): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294787779 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294787779 AND type='deeppockets_item' AND published='1'  LIMIT 1
125
(!!!!! 481343.03092957): (
				SELECT
					dp.id,
					dp.name,
					dp.title,
					dp.video,
					dp.video_source,
					dp.created

				FROM
					jos_deeppockets AS dp

				WHERE
					dp.video != ''
				AND
					dp.video_source != ''
				AND
					dp.cat = 10
				AND
					dp.published = 1
				AND
					dp.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			UNION
			(
				SELECT
					dpa.id,
					dpa.name,
					dpa.title,
					dpa.video,
					dpa.video_source,
					dpa.created

				FROM
					jos_deeppockets_archive AS dpa

				WHERE
					dpa.video != ''
				AND
					dpa.video_source != ''
				AND
					dpa.cat = 10
				AND
					dpa.published = 1
				AND
					dpa.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			ORDER BY
				created DESC

			LIMIT
				3
126
(114.91775512695): (
				SELECT
					dp.id,
					dp.name,
					dp.title,
					dp.video,
					dp.video_source,
					dp.created

				FROM
					jos_deeppockets AS dp

				WHERE
					dp.video != ''
				AND
					dp.video_source != ''
				AND
					dp.cat = 10
				AND
					dp.published = 1
				AND
					dp.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			UNION
			(
				SELECT
					dpa.id,
					dpa.name,
					dpa.title,
					dpa.video,
					dpa.video_source,
					dpa.created

				FROM
					jos_deeppockets_archive AS dpa

				WHERE
					dpa.video != ''
				AND
					dpa.video_source != ''
				AND
					dpa.cat = 10
				AND
					dpa.published = 1
				AND
					dpa.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			ORDER BY
				created DESC

			LIMIT
				3
127
(51.975250244141): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800513

			LIMIT 1
128
(37.908554077148): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800513

			LIMIT 1
129
(52.928924560547): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800359

			LIMIT 1
130
(37.908554077148): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800359

			LIMIT 1
131
(40.054321289062): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800361

			LIMIT 1
132
(36.001205444336): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800361

			LIMIT 1
133
(526.90505981445): SELECT *
                            FROM jos_deeppockets
                            WHERE 1=1 
                              AND id=294787779
                              AND (type='deeppockets_item' OR type='deeppockets_item_link')
                              AND published='1'
                            LIMIT 1
134
(412.94097900391): SELECT *
                            FROM jos_deeppockets_archive
                            WHERE 1=1 
                              AND id=294787779
                              AND (type='deeppockets_item' OR type='deeppockets_item_link')
                              AND published='1'
                            LIMIT 1
135
(211.00044250488): SELECT name FROM jos_deeppockets WHERE id=215
136
(47.922134399414): SELECT name FROM jos_deeppockets WHERE id=215
137
(643.96858215332): SELECT *,
    DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
    DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
    FROM jos_events
    WHERE state=1
    AND publish_up > NOW()
    and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) 
    ORDER BY publish_up ASC LIMIT 3
138
(628.94821166992): SELECT *,
    DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
    DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
    FROM jos_events
    WHERE state=1
    AND publish_up > NOW()
    and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) 
    ORDER BY publish_up ASC LIMIT 3
139
(104.90417480469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
140
(77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
141
(!!!!! 14611.959457397): TRUNCATE TABLE jos_trademed_module
142
(164.98565673828): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294787779
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
143
(86.069107055664): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294787779
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
144
(538.82598876953): SELECT *
   FROM jos_deeppockets
   WHERE 1=1 
   AND id=294787779
   AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
145
(63.896179199219): SELECT *
   FROM jos_deeppockets
   WHERE 1=1 
   AND id=294787779
   AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
146
(108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
147
(52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
148
(!!!!! 1401.9012451172): SELECT jos_item.*
						FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
						WHERE 1=1
						AND (jos_item.imgMini<>'')
						AND jos_item.type='L'
						AND jos_item.numberID= (
									 SELECT jos_number.id
									 FROM jos_number
									 WHERE jos_number.journalID IN (10)
						
									and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
									 ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
									 LIMIT 0,1
									 )
						ORDER BY RAND() DESC LIMIT 6
149
(120.16296386719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
150
(61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
151
(72.956085205078): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294787779 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294787779 AND type='deeppockets_item' AND published='1'  LIMIT 1
152
(49.829483032227): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=215 or channel_id is null)
153
(169.99244689941): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=215 or channel_id is null)
154
(49.114227294922): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1
155
(75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
156
(62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294787779 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294787779 AND published='1'
		LIMIT 1
157
(36.001205444336): select jos_twitters.link from jos_twitters where cat=10
158
(37.908554077148): select jos_facebook.link from jos_facebook where cat=10
159
(39.100646972656): select jos_google_plus.link from jos_google_plus where cat=10
160
(38.862228393555): select jos_linkedin.link from jos_linkedin where cat=10
161
(338.07754516602): update jos_bannersmanager_banner
			set impmade=impmade+1
			where id in(14615,14202,14203)
162
(!!!!! 1313.9247894287): insert into jos_banners_delta values (14615,'2025-06-18 16:03:01','216.73.216.120','view'),(14202,'2025-06-18 16:03:01','216.73.216.120','view'),(14203,'2025-06-18 16:03:01','216.73.216.120','view')