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Mammography Radiomics Can Help Classify Breast Masses

By MedImaging International staff writers
Posted on 25 Dec 2018
Image: A 50-year-old woman that has invasive cancer without (L) and with (R) radiologist and computer delineations (Photo courtesy Karen Drukker/ University of Chicago).
Image: A 50-year-old woman that has invasive cancer without (L) and with (R) radiologist and computer delineations (Photo courtesy Karen Drukker/ University of Chicago).
A new technique that combines three-compartment breast (3CB) image analysis and mammography radiomics could help reduce unnecessary breast biopsies, claims a new study.

Researchers at the University of Chicago (IL, USA), the University of California, San Francisco (UCSF; USA), and the Lee Moffitt Cancer Center and Research Institute (Tampa, FL, USA) conducted a prospective study involving 109 women (mean age 51 years) with category 4 or 5 breast masses. Dual-energy craniocaudal and mediolateral oblique mammograms were obtained immediately before biopsy to calculate the three quantitative compartments (water, lipid, and protein thickness) at each pixel. The masses were automatically segmented and features extracted from the low-energy mammograms and the quantitative compartment images.

Tenfold cross-validation was used to differentiate between the 35 malignant and 74 benign masses by means of water-lipid-protein composition images alone, mammography radiomics alone, and combined image analysis using both methods. The results revealed that a combination of 3CB image analysis and radiomics improved positive predictive value (PPV) from 32% for visual interpretation alone to almost 50%, with a concomitant 36% reduction in biopsies. The 3CB-radiomics missed just one of the 35 invasive cancers, a 97% sensitivity rate. The study was published on December 11, 2018, in Radiology.

“3CB can easily be added to mammography without requiring extensive modifications of existing equipment; the patient is already getting the mammography, plus we get all this extra information with only a ten percent additional dose of radiation,” said lead author Karen Drukker, PhD, of the University of Chicago department of radiology. “The combined 3CB-radiomics approach has the potential to play an increasingly prominent role in breast cancer diagnosis, and perhaps also screening.”

Radiomics is an extension of computer-aided diagnosis and refers to the comprehensive quantification of tumor phenotypes by extracting a large number of quantitative image features for data mining and precision medicine. In recent years radiomics has successfully extracted a variety of clinically relevant features, merging them into signatures, in order to estimate the probability of malignancy of identified breast cancer lesions.

Related Links:
University of Chicago
University of California, San Francisco
Lee Moffitt Cancer Center and Research Institute

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		LIMIT 1
50
(!!!!! 2669.095993042): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
51
(65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
52
(349.04479980469): SELECT name FROM jos_deeppockets WHERE id=294776226 LIMIT 1
53
(283.95652770996): SELECT name FROM jos_deeppockets_archive WHERE id=294776226 LIMIT 1
54
(65.088272094727): SELECT a.*
 FROM jos_components AS a
 WHERE ( a.admin_menu_link = 'option=com_syndicate' OR a.admin_menu_link = 'option=com_syndicate&hidemainmenu=1' )
 AND a.option = 'com_syndicate'
55
(87.976455688477): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294776226
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
56
(550.98533630371): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294776226
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
57
(!!!!! 2167.9401397705): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
58
(404.11949157715): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
59
(!!!!! 1749.0386962891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
60
(!!!!! 2954.9598693848): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
61
(!!!!! 3317.8329467773): select cover from jos_number
where journalid in (5) and cover is not null
order by left(issue,2)+right(issue,2)*12 desc limit 1
62
(962.0189666748): SELECT fid FROM jos_deeppockets WHERE id=294776226 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294776226 AND published='1'  LIMIT 1
63
(975.13198852539): SELECT id,name,sponsor_text
                    FROM jos_deeppockets dp
					left outer join jos_channel_sponsor cs
					on dp.id=cs.fid
                    WHERE cat=10
                    AND TYPE='file_folder'
                    AND published=1
                    AND id=215
                    ORDER BY `ordering`
64
(!!!!! 2178.9073944092): select jos_twitters.link from jos_twitters where cat=10
65
(!!!!! 1915.9317016602): select jos_facebook.link from jos_facebook where cat=10
66
(!!!!! 1031.1603546143): select jos_google_plus.link from jos_google_plus where cat=10
67
(725.03089904785): select jos_linkedin.link from jos_linkedin where cat=10
68
(!!!!! 1100.0633239746): SELECT fid FROM jos_deeppockets WHERE id=294776226 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294776226 AND published='1'  LIMIT 1
69
(!!!!! 2413.9881134033): SELECT id,name,sponsor_text
                    FROM jos_deeppockets dp
					left outer join jos_channel_sponsor cs
					on dp.id=cs.fid
                    WHERE cat=10
                    AND TYPE='file_folder'
                    AND published=1
                    AND id=215
                    ORDER BY `ordering`
70
(706.91108703613): SELECT fid FROM jos_deeppockets
								WHERE cat=10
								AND id=294776226
								AND (type='deeppockets_item' OR type='deeppockets_item_link') 
								AND published='1' 
								LIMIT 1
71
(!!!!! 3145.9331512451): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294776226 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
72
(!!!!! 3693.8190460205): SELECT id,name,title
 FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
			AND id != 294743300
			AND id != 294743301
			AND id != 294743302
			AND id != 294743303
			AND id != 294743304
			AND id != 294743305
			AND id != 294743306
			AND id != 294743307
			AND id != 294743308
			AND id != 294743309
			AND id != 294743310
			AND metakey != 'aacc'
		ORDER BY `ordering`
73
(79.154968261719): SELECT show_live FROM jos_com_show_setting LIMIT 1
74
(41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1
75
(44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1
76
(36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1
77
(36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1
78
(33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1
79
(39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1
80
(37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1
81
(37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1
82
(35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1
83
(36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1
84
(32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1
85
(54.836273193359): SELECT show_live FROM jos_com_show_setting LIMIT 1
86
(179.05235290527): SELECT show_live FROM jos_com_show_setting LIMIT 1
87
(!!!!! 2070.9037780762): SELECT fid FROM jos_deeppockets
								WHERE cat=10
								AND id=294776226
								AND (type='deeppockets_item' OR type='deeppockets_item_link') 
								AND published='1' 
								LIMIT 1
88
(119.92454528809): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294776226 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
89
(61.03515625): SELECT id,name,title
 FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
			AND id != 294743300
			AND id != 294743301
			AND id != 294743302
			AND id != 294743303
			AND id != 294743304
			AND id != 294743305
			AND id != 294743306
			AND id != 294743307
			AND id != 294743308
			AND id != 294743309
			AND id != 294743310
			AND metakey != 'aacc'
		ORDER BY `ordering`
90
(54.121017456055): SELECT show_live FROM jos_com_show_setting LIMIT 1
91
(37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1
92
(36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1
93
(36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1
94
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
95
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1
96
(32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1
97
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1
98
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
99
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
100
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
101
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1
102
(30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1
103
(46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1
104
(!!!!! 1432.1804046631): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
105
(63.180923461914): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
106
(61.988830566406): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294776226
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
107
(49.829483032227): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294776226
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
108
(449.89585876465): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
109
(108.95729064941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
110
(120.87821960449): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							
							AND dp.id=294776226
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
111
(478.02925109863): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								
								AND dp.id=294776226
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
112
(748.1575012207): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as ex
							ON ex.id = dp.author
							LEFT JOIN jos_deeppockets as dp2
							ON dp2.id = dp.fid
							WHERE dp.author != 0
							AND dp.cat = 10
							AND dp.published = 1
							AND (
								(dp.fid = 294743300)
								OR (dp.fid = 294743301)
								OR (dp.fid = 294743302)
								OR (dp.fid = 294743303)
								OR (dp.fid = 294743304)
								OR (dp.fid = 294743305)
								OR (dp.fid = 294743306)
								OR (dp.fid = 294743307)
								OR (dp.fid = 294743308)
								OR (dp.fid = 294743309)
								OR (dp.fid = 294743310)
								)
							ORDER BY RAND()
							LIMIT 1
113
(375.03242492676): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as ex
							ON ex.id = dp.author
							LEFT JOIN jos_deeppockets as dp2
							ON dp2.id = dp.fid
							WHERE dp.author != 0
							AND dp.cat = 10
							AND dp.published = 1
							AND (
								(dp.fid = 294743300)
								OR (dp.fid = 294743301)
								OR (dp.fid = 294743302)
								OR (dp.fid = 294743303)
								OR (dp.fid = 294743304)
								OR (dp.fid = 294743305)
								OR (dp.fid = 294743306)
								OR (dp.fid = 294743307)
								OR (dp.fid = 294743308)
								OR (dp.fid = 294743309)
								OR (dp.fid = 294743310)
								)
							ORDER BY RAND()
							LIMIT 1
114
(104.90417480469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
115
(77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
116
(128.03077697754): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
117
(66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
118
(212.9077911377): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
119
(56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
120
(975.13198852539): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`
121
(!!!!! 229618.07250977): SELECT
				*
			FROM
				jos_deeppockets
			WHERE
				jos_deeppockets.cat = 10
			AND
				jos_deeppockets.type = 'deeppockets_item'
			AND
				jos_deeppockets.published = 1
			AND
				jos_deeppockets.created + INTERVAL 14 DAY >= NOW()
			ORDER BY
				jos_deeppockets.hits DESC
			LIMIT
				7
122
(!!!!! 11564.016342163): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
123
(!!!!! 7936.0008239746): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
124
(!!!!! 7747.8885650635): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294776226 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294776226 AND type='deeppockets_item' AND published='1'  LIMIT 1
125
(!!!!! 1416641.9506073): (
				SELECT
					dp.id,
					dp.name,
					dp.title,
					dp.video,
					dp.video_source,
					dp.created

				FROM
					jos_deeppockets AS dp

				WHERE
					dp.video != ''
				AND
					dp.video_source != ''
				AND
					dp.cat = 10
				AND
					dp.published = 1
				AND
					dp.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			UNION
			(
				SELECT
					dpa.id,
					dpa.name,
					dpa.title,
					dpa.video,
					dpa.video_source,
					dpa.created

				FROM
					jos_deeppockets_archive AS dpa

				WHERE
					dpa.video != ''
				AND
					dpa.video_source != ''
				AND
					dpa.cat = 10
				AND
					dpa.published = 1
				AND
					dpa.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			ORDER BY
				created DESC

			LIMIT
				3
126
(137.0906829834): (
				SELECT
					dp.id,
					dp.name,
					dp.title,
					dp.video,
					dp.video_source,
					dp.created

				FROM
					jos_deeppockets AS dp

				WHERE
					dp.video != ''
				AND
					dp.video_source != ''
				AND
					dp.cat = 10
				AND
					dp.published = 1
				AND
					dp.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			UNION
			(
				SELECT
					dpa.id,
					dpa.name,
					dpa.title,
					dpa.video,
					dpa.video_source,
					dpa.created

				FROM
					jos_deeppockets_archive AS dpa

				WHERE
					dpa.video != ''
				AND
					dpa.video_source != ''
				AND
					dpa.cat = 10
				AND
					dpa.published = 1
				AND
					dpa.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			ORDER BY
				created DESC

			LIMIT
				3
127
(323.05717468262): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800513

			LIMIT 1
128
(118.97087097168): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800513

			LIMIT 1
129
(178.81393432617): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800359

			LIMIT 1
130
(90.122222900391): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800359

			LIMIT 1
131
(!!!!! 1935.9588623047): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800361

			LIMIT 1
132
(!!!!! 2136.9457244873): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800361

			LIMIT 1
133
(360.01205444336): SELECT *
                            FROM jos_deeppockets
                            WHERE 1=1 
                              AND id=294776226
                              AND (type='deeppockets_item' OR type='deeppockets_item_link')
                              AND published='1'
                            LIMIT 1
134
(331.87866210938): SELECT *
                            FROM jos_deeppockets_archive
                            WHERE 1=1 
                              AND id=294776226
                              AND (type='deeppockets_item' OR type='deeppockets_item_link')
                              AND published='1'
                            LIMIT 1
135
(308.03680419922): SELECT name FROM jos_deeppockets WHERE id=215
136
(249.86267089844): SELECT name FROM jos_deeppockets WHERE id=215
137
(494.95697021484): SELECT *,
    DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
    DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
    FROM jos_events
    WHERE state=1
    AND publish_up > NOW()
    and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) 
    ORDER BY publish_up ASC LIMIT 3
138
(!!!!! 1656.0554504395): SELECT *,
    DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
    DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
    FROM jos_events
    WHERE state=1
    AND publish_up > NOW()
    and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) 
    ORDER BY publish_up ASC LIMIT 3
139
(646.11434936523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
140
(830.88874816895): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
141
(!!!!! 11394.023895264): TRUNCATE TABLE jos_trademed_module
142
(262.02201843262): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294776226
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
143
(!!!!! 7563.1141662598): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294776226
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
144
(!!!!! 2249.002456665): SELECT *
   FROM jos_deeppockets
   WHERE 1=1 
   AND id=294776226
   AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
145
(98.943710327148): SELECT *
   FROM jos_deeppockets
   WHERE 1=1 
   AND id=294776226
   AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
146
(246.04797363281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
147
(44.822692871094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
148
(!!!!! 2111.9117736816): SELECT jos_item.*
						FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
						WHERE 1=1
						AND (jos_item.imgMini<>'')
						AND jos_item.type='L'
						AND jos_item.numberID= (
									 SELECT jos_number.id
									 FROM jos_number
									 WHERE jos_number.journalID IN (10)
						
									and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
									 ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
									 LIMIT 0,1
									 )
						ORDER BY RAND() DESC LIMIT 6
149
(249.86267089844): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
150
(138.99803161621): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
151
(!!!!! 2103.0902862549): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294776226 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294776226 AND type='deeppockets_item' AND published='1'  LIMIT 1
152
(118.01719665527): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=215 or channel_id is null)
153
(30.040740966797): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=215 or channel_id is null)
154
(164.98565673828): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1
155
(500.91743469238): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
156
(56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776226 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776226 AND published='1'
		LIMIT 1
157
(108.00361633301): select jos_twitters.link from jos_twitters where cat=10
158
(171.89979553223): select jos_facebook.link from jos_facebook where cat=10
159
(28.133392333984): select jos_google_plus.link from jos_google_plus where cat=10
160
(517.12989807129): select jos_linkedin.link from jos_linkedin where cat=10
161
(!!!!! 1061.2010955811): update jos_bannersmanager_banner
			set impmade=impmade+1
			where id in(14615,14202,14203)
162
(!!!!! 4970.0736999512): insert into jos_banners_delta values (14615,'2025-06-19 23:08:16','216.73.216.120','view'),(14202,'2025-06-19 23:08:16','216.73.216.120','view'),(14203,'2025-06-19 23:08:16','216.73.216.120','view')