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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

Handheld Probe Generates Precise Images Without Bulky, Costly Instruments

By MedImaging International staff writers
Posted on 17 Nov 2014

Image: Photoacoustic/ultrasound images taken with the new system show a human finger joint from different angles. The images on the right (b and d) show anatomic structures revealed by the ultrasound. The images on the left (a and c) show the photoacoustics data overlaying the ultrasound data. The bright yellow and red at the top of the finger show the skin and blood vessels running parallel to the finger (Photo courtesy of Pim van den Berg/Khalid Daoudi).

Image: The new imaging system consists of a handheld probe (on the right), and an ultrasound scanning display system (on the left). It can be easily transported between rooms in a clinic (Photo courtesy of Pim van den Berg/Khalid Daoudi).

A new handheld probe developed by university and industry researchers in the Netherlands and France could give clinicians useful new imaging capabilities that fit in the palms of their hands. A technology that once filled up a whole lab bench has been shrunken down to a computer screen and a small probe approximately the size of a stapler.

The new device combines two imaging modalities: ultrasound and photoacoustics. Ultrasound is a well-accepted technology that analyzes how sound pulses echo off internal body parts. It is suitable for revealing anatomic structures and is, perhaps most familiarly, used to image a developing fetus in a mother’s womb. The device was described October 20, 2014, in a paper published in The Optical Society’s (OSA) open-access journal Optics Express.

Photoacoustics is a relatively new imaging technique, still making its way toward widespread clinical applications. In photoacoustic imaging, short pulses of light heat up internal tissue. The slight temperature change leads to an alteration in pressure, which then produces a wave of ultrasound that can be examined to show data about the body’s internal workings. Since this technique ultimately produces ultrasound waves as well, existing technology can be used to analyze and display the images.

The advantage of photoacoustics is that it can reveal important medical information that other imaging techniques cannot, including the presence of molecules such as hemoglobin and melanin and the submillimeter structure of complexes of blood vessels several centimeters beneath the skin. When combined with spectroscopic measurements, photoacoustics can also quantify hemoglobin oxygen saturation within single vessels, providing metabolic information that could be helpful for monitoring tumor progression.

However, in spite of these benefits, the cost and size of most photoacoustic systems restrict their widespread use, according to Dr. Khalid Daoudi, a researcher in the biomedical photonic imaging group at the University of Twente (Enschede, the Netherlands). Most systems on the market require expensive and cumbersome lasers that make the systems unfeasible for point-of-care (POC) diagnostics. “Our research aimed to break through these hindering factors,” Dr. Daoudi said.

The project began as collaboration between the University of Twente and three European companies: Esaote Europe (Maastricht, The Netherlands), a maker of medical diagnostic systems, Quantel (Newbury, Berkshire, UK), a maker of solid-state lasers, and SILIOS Technologies (Peynier, France), a developer of optical components.

The investigators’ major development, which allowed them to drastically shrink the system, was the design of an ultra-compact laser based on an effective and inexpensive laser diode. By stacking multiple diodes to raise the power and carefully designing optical elements to shape the laser beam, the scientists were able to generate laser pulses with energies higher than had ever been achieved before with diode technology.

Diode lasers can also provide many laser pulses per second, which in turn allows real time imaging, another advantage of the new system, Dr. Daoudi noted. The researchers evaluated the imaging performance of the system in different types of phantoms and in a healthy human finger joint. The new compact probe and imaging system can be easily transported between rooms in a clinical environment, an appealing feature for future commercialization, the researchers reported.

The researchers are now working with a European consortium of industrial and academic partners to take the next phase, moving the research to commercialization. The current system operates at a single wavelength in the near infrared, but the team has plans to expand the design to multi-wavelength imaging. “Some applications targeted are rheumatoid arthritis in finger joints, oncology, cardiovascular disease and burn wounds,” Dr. Daoudi said.

Related Links:
University of Twente
Esaote Europe
Quantel

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58 (100.13580322266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

59 (267.98248291016): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

60 (110.86463928223): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

61 (!!!!! 5445.0035095215): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (759.84001159668): SELECT fid FROM jos_deeppockets WHERE id=294755720 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294755720 AND published='1' LIMIT 1

63 (83.92333984375): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=215 ORDER BY `ordering`

64 (82.015991210938): select jos_twitters.link from jos_twitters where cat=10

65 (34.093856811523): select jos_facebook.link from jos_facebook where cat=10

66 (34.093856811523): select jos_google_plus.link from jos_google_plus where cat=10

67 (30.994415283203): select jos_linkedin.link from jos_linkedin where cat=10

68 (47.922134399414): SELECT fid FROM jos_deeppockets WHERE id=294755720 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294755720 AND published='1' LIMIT 1

69 (36.954879760742): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=215 ORDER BY `ordering`

70 (509.97734069824): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755720 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (436.06758117676): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755720 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (68.902969360352): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (79.870223999023): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (107.0499420166): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755720 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (45.061111450195): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755720 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (47.922134399414): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (193.11904907227): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (!!!!! 3849.983215332): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (133.99124145508): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (65.803527832031): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (115.15617370605): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

105 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

106 (87.976455688477): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755720 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (783.92028808594): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755720 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 6154.0603637695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

109 (155.92575073242): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

110 (271.08192443848): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294755720 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 4645.824432373): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294755720 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 1148.9391326904): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (802.04010009766): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (612.02049255371): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

115 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

116 (109.91096496582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

117 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

118 (105.14259338379): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

119 (728.84559631348): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

120 (87.02278137207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

121 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

122 (542.87910461426): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 68058.013916016): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 2511.0244750977): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755720 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755720 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 31507.968902588): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (429.15344238281): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (174.99923706055): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (509.02366638184): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (358.10470581055): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (471.11511230469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (!!!!! 1605.0338745117): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (58.889389038086): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (65.088272094727): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (49.114227294922): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (723.12355041504): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (925.06408691406): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (375.98609924316): SELECT name FROM jos_deeppockets WHERE id=215

138 (48.160552978516): SELECT name FROM jos_deeppockets WHERE id=215

139 (929.11720275879): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (807.04689025879): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (201.94053649902): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

142 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

143 (!!!!! 6489.9921417236): TRUNCATE TABLE jos_trademed_module

144 (140.90538024902): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755720 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (78.916549682617): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755720 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (422.00088500977): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (294.92378234863): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (!!!!! 3668.0698394775): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

149 (122.0703125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

150 (!!!!! 1724.0047454834): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

152 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

153 (84.877014160156): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755720 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755720 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (36.001205444336): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

155 (36.001205444336): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

156 (36.001205444336): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (194.07272338867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

158 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755720 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755720 AND published='1' LIMIT 1

159 (48.160552978516): select jos_twitters.link from jos_twitters where cat=10

160 (35.04753112793): select jos_facebook.link from jos_facebook where cat=10

161 (39.815902709961): select jos_google_plus.link from jos_google_plus where cat=10

162 (34.093856811523): select jos_linkedin.link from jos_linkedin where cat=10

163 (!!!!! 1404.0470123291): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14202,14203)

164 (!!!!! 2086.877822876): insert into jos_banners_delta values (14202,'2025-06-23 11:30:08','216.73.216.120','view'),(14203,'2025-06-23 11:30:08','216.73.216.120','view')

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