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27 Jul 2025 - 30 Jul 2025

AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

Molecular Imaging Meet Shows Biomarkers Key to Early Detection of Cancer, Heart Disease, Alzheimer’s

By MedImaging International staff writers
Posted on 10 Oct 2013

Advances in noninvasive imaging technology to detect molecular biomarkers in science were presented at an international molecular imaging meeting.

The World Molecular Imaging Congress (WMIC) 2013 was held in September held in Savannah, GA, USA. Using a multimodality imaging approach, Dr. Bernd Pichler and colleagues from the University of Tubingen (Germany) detected an important protein biomarker that is related to decreased brain perfusion during the progression of Alzheimer’s disease (AD), which may lead to earlier identification and monitoring of disease progression. Findings of the study add critical information into disease progression and growth that may improve the ability to identify ideal therapeutic windows for amyloid targeting therapies.

One of the goals of molecular imaging in oncology is to develop imaging probes that target the tumor with high sensitivity and specificity. The discovery of effective cell-surface markers for lung cancer is a key first step in the development of lung cancer specific molecular imaging probes. Fluorescently-labeled targeted probes can be designed for real-time surgical guidance. In the study, Dr. David Morse and colleagues at the Moffitt Cancer Center (Tampa, FL, USA), presented findings about the detection of cell-surface protein biomarkers in lung tumors using optical imaging techniques. The fluorescent Dmt-Tic probes revealed high selectivity and affinity for the δ-opioid receptor, which should enable the use of these probes for guidance during lung cancer resection.

As another instance of the many oncology biomarkers presented at the WMIC, protein biomarkers that stimulate the growth of breast tumors have been detected using ultrasound imaging by Dr. Juergen Willman and collaborators from Stanford University (Stanford, CA, USA) in their study. Findings suggest that VEGFR [vascular endothelial growth factor receptor]2-targeted ultrasound molecular imaging allows for a very accurate and effective detection of DCIS (ductal carcinoma in situ; or also known as intraductal carcinoma), the most typical type of noninvasive breast cancer in a transgenic mouse model. Imaging tumor angiogenesis on a molecular level using ultrasound molecular imaging may be a promising approach for earlier detection and improved characterization of breast cancer in future clinical trials.

The use of nanoparticles from drug delivery is well established in the oncology field; however, there are limited findings on the use in atherosclerotic plaque. In the study, Dr. Zahi Fayad and collaborators, from Mount Sinai School of Medicine (New York, NY, USA), investigated the use of an innovative nanosized iron particle to target a protein biomarker in atherosclerotic plaque deposits in blood vessels, which could improve the ability to detect and diagnose the disease before the plaque can rupture and cause a heart attack. Results demonstrated uptake in atherosclerosis is very similar to targeting in cancer, suggesting that nanoparticles may also be effective for drug delivery to atherosclerotic plaques. The findings also demonstrated that three-dimensional (3D) contrast-enhanced MRI can be used to detect these nanoparticles in the plaques.

“Proteins are the machines that perform almost all functions within the body, including tumors. Detecting protein biomarkers, the key cogs within the protein machinery, can lead to earlier diagnoses of heart disease, cancer and other conditions and provide outstanding targets for therapies. The significant advances in imaging molecular biomarkers being presented at this year’s World Molecular Imaging Congress, demonstrate the progress towards early disease diagnoses that will impact healthcare,” said Marty Pagel, PhD, from the University of Arizona Cancer Center (Tucson, USA).

This year’s World Molecular Imaging Congress program consisted of 168 oral presentations and 35 spotlight presentations highlighting five categories: chemistry and imaging probes, first-in-human and clinical studies, preclinical cell and tissue level studies, preclinical in vivo studies, technology and software development, with over 60 industry exhibitors.

Related Links:
World Molecular Imaging Congress
University of Tubingen
Mount Sinai School of Medicine

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60 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

61 (134.94491577148): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (681.16188049316): SELECT fid FROM jos_deeppockets WHERE id=294748593 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294748593 AND published='1' LIMIT 1

63 (401.97372436523): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=215 ORDER BY `ordering`

64 (77.962875366211): select jos_twitters.link from jos_twitters where cat=10

65 (45.061111450195): select jos_facebook.link from jos_facebook where cat=10

66 (50.067901611328): select jos_google_plus.link from jos_google_plus where cat=10

67 (44.822692871094): select jos_linkedin.link from jos_linkedin where cat=10

68 (68.902969360352): SELECT fid FROM jos_deeppockets WHERE id=294748593 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294748593 AND published='1' LIMIT 1

69 (43.869018554688): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=215 ORDER BY `ordering`

70 (425.10032653809): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294748593 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (459.19418334961): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294748593 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (76.770782470703): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (70.810317993164): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (57.93571472168): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294748593 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (30.994415283203): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294748593 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (33.855438232422): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (72.002410888672): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (70.810317993164): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

105 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

106 (61.988830566406): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294748593 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (47.922134399414): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294748593 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

109 (59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

110 (63.896179199219): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294748593 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (526.90505981445): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294748593 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (658.03527832031): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (470.16143798828): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (101.08947753906): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

115 (79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

116 (133.03756713867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

117 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

118 (81.062316894531): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

119 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

120 (104.90417480469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

121 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

122 (273.9429473877): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 22968.053817749): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (510.93101501465): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294748593 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294748593 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 9001.0166168213): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (133.03756713867): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (97.036361694336): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (50.067901611328): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (77.009201049805): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (434.87548828125): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (44.107437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (67.949295043945): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (40.054321289062): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (509.97734069824): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (495.91064453125): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (252.96211242676): SELECT name FROM jos_deeppockets WHERE id=215

138 (39.100646972656): SELECT name FROM jos_deeppockets WHERE id=215

139 (610.8283996582): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (543.11752319336): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (88.930130004883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

142 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

143 (!!!!! 10071.039199829): TRUNCATE TABLE jos_trademed_module

144 (139.95170593262): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294748593 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (67.949295043945): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294748593 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (945.8065032959): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

149 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

150 (!!!!! 1379.9667358398): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

152 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

153 (59.843063354492): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294748593 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294748593 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (468.01567077637): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

155 (41.961669921875): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

156 (36.954879760742): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (192.16537475586): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

158 (70.095062255859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294748593 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294748593 AND published='1' LIMIT 1

159 (60.081481933594): select jos_twitters.link from jos_twitters where cat=10

160 (45.061111450195): select jos_facebook.link from jos_facebook where cat=10

161 (46.014785766602): select jos_google_plus.link from jos_google_plus where cat=10

162 (41.007995605469): select jos_linkedin.link from jos_linkedin where cat=10

163 (270.84350585938): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14202,14203)

164 (!!!!! 1503.9443969727): insert into jos_banners_delta values (14202,'2025-06-23 18:27:15','216.73.216.120','view'),(14203,'2025-06-23 18:27:15','216.73.216.120','view')

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