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Mechanical Elasticity Imaging System Provides Real-Time Prostate Mapping

By MedImaging International staff writers
Posted on 08 May 2012

A prostate mechanical imaging (PMI) system creates color two-dimensional (2D) and 3D maps of the prostate in real time such that when in agreement with a digital rectal examination (DRE) finding, can be permanently stored in electronic records for future analysis and comparison. More...

ProUroCare Medical, Inc. (Minneapolis, St. Paul, MN, USA), a provider of medical imaging products, reported it has received clearance from the US Food & Drug Administration (FDA) for its ProUroScan PMI system. The approval opens the way for men and their families to receive high-resolution visual documentations as an aid in detecting prostate abnormalities that were previously detected by DRE.

ProUroCare’s patented tactile elasticity imaging technology, which uses a handheld pressure-sensing rectal probe and advanced image construction software to produce its prostate maps, represents a new imaging modality distinct from conventional ultrasound imaging.

The company plans to introduce the technology in 2012 to a limited number of major US medical care centers in key major metropolitan markets. ProUroCare has been actively seeking a strategic corporate partner with a strong sales and in-service support presence in the urologic market to fully commercialize its technology.

“This is a major milestone for the company, for physicians looking for more assurance and documentation in their evaluations and for men eager for more information to assess and make decisions about their prostate health,” said Rick Carlson, CEO of ProUroCare Medical. “A color image can go a long way in documenting a person’s prostate condition, and this development puts us one step closer to supplementing other screening measures with a helpful, high quality visual aid that can be referred and compared to over time.”

As a standard of care, the American Urological Association (AUA) currently recommends that beginning at age 40, men receive a DRE and a prostate-specific antigen (PSA) blood test in their annual physical exam, however data from community-based studies suggest the positive predictive values of DRE and PSA combined achieve only a 56% predictive value. Furthermore, neither test creates a physical or visual record of the prostate. The ProUroScan system is being introduced as an adjunctive technology to a DRE for physicians to use to additionally clarify and validate abnormalities associated with the prostate gland.

“Having a visual aid of irregularities can be so helpful to physicians and patients, particularly in the area of prostate care where decision-making is often difficult,” said Dr. Robert Weiss, a urologic oncologist with the Cancer Institute of New Jersey (New Brunswick, NJ, USA) and a faculty member at Robert Wood Johnson Medical School (New Brunswick, NJ, USA), who used the ProUroScan technology as part of its clinical trial process. “The quality and resolution of the images are excellent, providing an immensely valuable supplement to the DRE, where physicians must rely on a gloved finger to feel for changes in the size and shape of the gland.”

The FDA filings were supported by data from a 2009 National Institute of Health and National Cancer Institute-supported clinical study of patients evaluated at five leading US medical centers, as well as an earlier study conducted specifically at the Robert Wood Johnson Medical Center.

ProUroCare Medical is a company engaged in the business of creating novel medical imaging products. Approved to make real-time, color images of men’s prostate glands, ProUroCare will next pilot the clinical technology in select medical centers.

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58 (!!!!! 7438.8980865479): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

59 (!!!!! 7957.935333252): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

60 (!!!!! 9685.9931945801): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

61 (572.91984558105): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

62 (!!!!! 4716.8731689453): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

63 (!!!!! 1220.9415435791): SELECT fid FROM jos_deeppockets WHERE id=294740507 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294740507 AND published='1' LIMIT 1

64 (435.11390686035): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=215 ORDER BY `ordering`

65 (292.06275939941): select jos_twitters.link from jos_twitters where cat=10

66 (177.14500427246): select jos_facebook.link from jos_facebook where cat=10

67 (!!!!! 4803.8959503174): select jos_google_plus.link from jos_google_plus where cat=10

68 (221.01402282715): select jos_linkedin.link from jos_linkedin where cat=10

69 (239.13383483887): SELECT fid FROM jos_deeppockets WHERE id=294740507 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294740507 AND published='1' LIMIT 1

70 (!!!!! 1282.9303741455): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=215 ORDER BY `ordering`

71 (!!!!! 2442.1215057373): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294740507 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (!!!!! 8053.0643463135): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294740507 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (!!!!! 1955.0323486328): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

74 (!!!!! 3252.9830932617): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (696.18225097656): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (543.11752319336): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (648.02169799805): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (622.03407287598): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (943.89915466309): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (233.88862609863): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (615.11993408203): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (357.86628723145): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294740507 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (!!!!! 1351.1180877686): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294740507 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (770.09201049805): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

91 (368.11828613281): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (136.8522644043): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (149.96528625488): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (86.069107055664): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (164.98565673828): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (123.97766113281): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (133.99124145508): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (144.95849609375): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (725.03089904785): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

106 (!!!!! 5198.9555358887): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

107 (212.9077911377): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294740507 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (56.028366088867): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294740507 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (694.99015808105): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

110 (264.88304138184): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

111 (!!!!! 4082.9181671143): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294740507 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (552.89268493652): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294740507 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (!!!!! 7558.1073760986): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (!!!!! 7989.1681671143): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (!!!!! 7809.1621398926): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

116 (!!!!! 7947.9217529297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

117 (!!!!! 7660.1505279541): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

118 (!!!!! 7955.0743103027): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

119 (!!!!! 7764.1010284424): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

120 (!!!!! 7950.0675201416): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

121 (!!!!! 7734.0602874756): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

122 (!!!!! 7936.0008239746): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

123 (!!!!! 3306.8656921387): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

124 (!!!!! 55783.033370972): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

125 (!!!!! 1736.8793487549): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294740507 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294740507 AND type='deeppockets_item' AND published='1' LIMIT 1

126 (!!!!! 20237.922668457): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (142.09747314453): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (!!!!! 4359.9605560303): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (219.10667419434): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (761.98577880859): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (244.140625): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (449.89585876465): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (51.975250244141): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (252.00843811035): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (288.00964355469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (!!!!! 2651.9298553467): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (!!!!! 6711.9598388672): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (!!!!! 1353.0254364014): SELECT name FROM jos_deeppockets WHERE id=215

139 (228.1665802002): SELECT name FROM jos_deeppockets WHERE id=215

140 (547.88589477539): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (849.00856018066): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (!!!!! 1372.0989227295): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

143 (295.16220092773): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

144 (!!!!! 6007.194519043): TRUNCATE TABLE jos_trademed_module

145 (!!!!! 7084.1312408447): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294740507 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 7869.9588775635): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294740507 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (!!!!! 1393.0797576904): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (!!!!! 1168.0126190186): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (!!!!! 3684.0438842773): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

150 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

151 (!!!!! 4611.9689941406): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

152 (622.03407287598): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

153 (807.04689025879): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

154 (!!!!! 1092.9107666016): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294740507 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294740507 AND type='deeppockets_item' AND published='1' LIMIT 1

155 (51.021575927734): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

156 (142.81272888184): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

157 (295.16220092773): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

158 (357.15103149414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

159 (915.0505065918): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740507 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740507 AND published='1' LIMIT 1

160 (!!!!! 2677.9174804688): select jos_twitters.link from jos_twitters where cat=10

161 (47.922134399414): select jos_facebook.link from jos_facebook where cat=10

162 (32.186508178711): select jos_google_plus.link from jos_google_plus where cat=10

163 (29.087066650391): select jos_linkedin.link from jos_linkedin where cat=10

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