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Deep Learning Technique Could Reveal Transparent Features in Medical Images

By MedImaging International staff writers
Posted on 31 Dec 2018

Image: From an original transparent etching (far right), engineers produced a photograph in the dark (top left), then attempted to reconstruct the object using first a physics-based algorithm (top right), then a trained neural network (bottom left), before combining both the neural network with the physics-based algorithm to produce the clearest, most accurate reproduction (bottom right) of the original object (Photo courtesy of MIT).

Engineers at the Massachusetts Institute of Technology (Cambridge, MA, USA) have developed a deep learning technique that can reveal images of transparent features or objects that are nearly impossible to decipher in almost total darkness.

Deep neural networks have been widely applied in the field of computer vision and image recognition. The MIT engineers recently developed neural networks to reconstruct transparent objects in images taken with plenty of light. However, they became the first to use deep neural networks in experiments to reveal invisible objects in images taken in the dark.

In their study, the researchers reconstructed transparent objects from images of those objects, taken in almost pitch-black conditions using a “deep neural network.” This machine-learning technique involves training a computer to associate certain inputs with specific outputs — in this case, dark, grainy images of transparent objects and the objects themselves.

The researchers trained a computer to recognize more than 10,000 transparent glass-like etchings, based on extremely grainy images of those patterns. The images were taken in very low lighting conditions, with about one photon per pixel — far less light than a camera would register in a dark, sealed room. They then showed the computer a new grainy image, not included in the training data, and found that it learned to reconstruct the transparent object that the darkness had obscured.

The researchers repeated their experiments with a totally new dataset, consisting of more than 10,000 images of more general and varied objects, including people, places, and animals. After training, the researchers fed the neural network a completely new image, taken in the dark, of a transparent etching of a scene with gondolas docked at a pier. The once again found that the physics-informed reconstruction produced a more accurate image of the original, compared to reproductions without the physical law embedded. The results demonstrate that deep neural networks can be used to illuminate transparent features such as biological tissues and cells, in images taken with very little light.

“We have shown that deep learning can reveal invisible objects in the dark,” said the study’s lead author Alexandre Goy. “This result is of practical importance for medical imaging to lower the exposure of the patient to harmful radiation, and for astronomical imaging.”

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70 (950.81329345703): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294776286 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (381.9465637207): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294776286 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (48.87580871582): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (68.902969360352): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294776286 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (422.00088500977): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294776286 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (69.141387939453): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (113.96408081055): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (72.002410888672): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (24.080276489258): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (120.87821960449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

105 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

106 (63.896179199219): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294776286 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (46.968460083008): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294776286 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 4395.9617614746): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

109 (117.06352233887): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

110 (54.121017456055): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294776286 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (477.07557678223): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294776286 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (528.09715270996): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (323.05717468262): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

115 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

116 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

117 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

118 (107.0499420166): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

119 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

120 (262.02201843262): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 33998.012542725): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (197.8874206543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

123 (!!!!! 4383.0871582031): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

124 (597.00012207031): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294776286 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294776286 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 599863.05236816): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (184.05914306641): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (132.08389282227): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (131.13021850586): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (137.0906829834): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (135.89859008789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (125.88500976562): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (128.03077697754): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (!!!!! 2290.0104522705): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (569.10514831543): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (77.962875366211): SELECT name FROM jos_deeppockets WHERE id=217

136 (36.001205444336): SELECT name FROM jos_deeppockets WHERE id=217

137 (712.15629577637): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))217((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (432.96813964844): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))217((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (112.05673217773): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

140 (98.943710327148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

141 (!!!!! 7213.1156921387): TRUNCATE TABLE jos_trademed_module

142 (141.85905456543): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294776286 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (760.07843017578): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294776286 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (414.13307189941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (387.90702819824): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (715.97099304199): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

147 (262.97569274902): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

148 (!!!!! 1232.8624725342): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (118.97087097168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

150 (89.168548583984): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

151 (441.07437133789): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294776286 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294776286 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (105.85784912109): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=217 or channel_id is null)

153 (144.00482177734): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=217 or channel_id is null)

154 (422.00088500977): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (335.9317779541): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

156 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294776286 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294776286 AND published='1' LIMIT 1

157 (37.908554077148): select jos_twitters.link from jos_twitters where cat=10

158 (45.061111450195): select jos_facebook.link from jos_facebook where cat=10

159 (37.193298339844): select jos_google_plus.link from jos_google_plus where cat=10

160 (29.087066650391): select jos_linkedin.link from jos_linkedin where cat=10

161 (301.12266540527): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 1343.0118560791): insert into jos_banners_delta values (14615,'2025-05-02 09:22:56','18.191.136.109','view'),(14202,'2025-05-02 09:22:56','18.191.136.109','view'),(14203,'2025-05-02 09:22:56','18.191.136.109','view')

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