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Breast Cancer Screening Machine Learning Software Receives CE Mark

By MedImaging International staff writers
Posted on 15 Oct 2018

A new deep learning-based breast cancer screening software has received the CE mark and will be launched within the UK’s National Health Service (NHS) and European healthcare systems. The software has been developed by Kheiron Medical Technologies (London, UK), a start-up that combines novel deep learning methods, data science, and radiology expertise to enable diagnostics designed to detect cancers and improve patient outcomes.

Deep learning uses powerful artificial neural networks and high performance computing to analyze complex medical images with precision. Kheiron’s breast cancer screening software aims to facilitate more efficient and accurate breast cancer detection at an earlier stage of the disease and reduce the number of women incorrectly subjected to invasive biopsies, unnecessary radiation and detect more cancers at the crucial early stages. In an independent multi-center clinical study to evaluate its performance prior to submission for CE approval, the deep learning- software demonstrated indications of performance above the average national benchmarks for breast screening radiologists.

With the CE regulatory approval, health care providers in Europe will now be able to use Kheiron’s breast cancer screening software as a second reader of mammographic images in a breast cancer screening setting. Clinicians will be able to receive results within seconds, directly into their existing workflows, incorporating case-wise recall decision support and lesion localization. By using the software as a second reader, the screening workload of overstretched clinical staff in all screening settings will potentially reduce, allowing them to focus on other more complex modalities and tasks. Additionally, the CE marking will allow for intelligent triaging of imaging studies prior to review, enabling radiologists to prioritize studies based on the algorithm’s findings.

“With UK radiology workforce shortages in the spotlight, regulatory approval could actually position the UK and Europe as the world’s earliest adopters of AI at scale,” said Kheiron’s Chief Medical Officer, Dr. Christopher Austin. “European national breast screening programs can now take the lead and demonstrate how to leverage high quality, proven, and safe machine learning technologies to run screening programs better, smarter and more cost-effectively for millions of women.”

“These are exciting times for the breast imaging community and in particular breast screening,” said Dr Nisha Sharma, Consultant Breast Radiologist, Director of Breast Screening & Clinical Lead for Breast Imaging at Leeds University Hospitals Trust, and Secretary for the British Society of Breast Imaging. “Software such as this will have a significant impact in managing the global workforce shortage in mammography by augmenting single reading and ensuring that the sensitivity and specificity of double reading are at least maintained and potentially improved. This would reinforce the aim that deep learning tools are there to support the clinician and work alongside them.”

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69 (43.153762817383): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=217 ORDER BY `ordering`

70 (428.91502380371): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294775268 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (321.86508178711): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294775268 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (54.121017456055): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (77.962875366211): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (37.193298339844): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (69.856643676758): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294775268 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (39.815902709961): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294775268 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (44.822692871094): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (75.101852416992): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 2939.9394989014): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

105 (114.91775512695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

106 (81.062316894531): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294775268 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (633.95500183105): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294775268 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (101.08947753906): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

109 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

110 (82.969665527344): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294775268 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (720.97778320312): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294775268 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (832.08084106445): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (586.03286743164): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (104.90417480469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

115 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

116 (120.87821960449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

117 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

118 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

119 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

120 (394.10591125488): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 61683.893203735): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (578.88031005859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

123 (287.05596923828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

124 (909.09004211426): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294775268 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294775268 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 1005517.0059204): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (123.97766113281): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (67.949295043945): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (48.87580871582): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (72.002410888672): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (42.915344238281): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (48.87580871582): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (782.01293945312): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (668.04885864258): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (68.187713623047): SELECT name FROM jos_deeppockets WHERE id=217

136 (43.869018554688): SELECT name FROM jos_deeppockets WHERE id=217

137 (694.99015808105): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))217((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (638.00811767578): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))217((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (103.95050048828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

140 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

141 (!!!!! 13724.088668823): TRUNCATE TABLE jos_trademed_module

142 (156.16416931152): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294775268 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (113.01040649414): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294775268 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (604.86793518066): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (101.80473327637): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

147 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

148 (!!!!! 1758.0986022949): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (114.91775512695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

150 (87.976455688477): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

151 (60.081481933594): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294775268 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294775268 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (46.968460083008): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=217 or channel_id is null)

153 (40.054321289062): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=217 or channel_id is null)

154 (60.796737670898): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (98.943710327148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

156 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294775268 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294775268 AND published='1' LIMIT 1

157 (73.909759521484): select jos_twitters.link from jos_twitters where cat=10

158 (40.054321289062): select jos_facebook.link from jos_facebook where cat=10

159 (38.862228393555): select jos_google_plus.link from jos_google_plus where cat=10

160 (41.961669921875): select jos_linkedin.link from jos_linkedin where cat=10

161 (430.10711669922): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 1456.9759368896): insert into jos_banners_delta values (14615,'2025-06-17 19:19:01','216.73.216.120','view'),(14202,'2025-06-17 19:19:01','216.73.216.120','view'),(14203,'2025-06-17 19:19:01','216.73.216.120','view')

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