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Machine-Learning Scans Accurately Predict Undiagnosed Dementia

By MedImaging International staff writers
Posted on 29 Aug 2018

Image: A brain scan showing vascular dementia (Photo courtesy of Radiopaedia).

Researchers from the University of Plymouth (Devon, UK) have developed a new machine-learning model that scanned routinely collected National Health Service {(NHS) England, UK)} data in a study and predicted undiagnosed dementia in primary care with high accuracy.

For the study, the researchers used Read-encoded data from 18 consenting GP surgeries across Devon, UK, for 26,483 patients aged over 65 years. The Read codes is a thesaurus of clinical terms used to summarize clinical and administrative data for UK GPs and were assessed on whether they can contribute to dementia risk, along with other factors such as weight and blood pressure. The researchers used the codes to train the machine-learning classification model to identify patients with possible underlying dementia. The study found that the model can detect people with underlying dementia with an accuracy of 84%, suggesting that it could significantly reduce the number of people living with undiagnosed dementia from the current estimated figure of 50% to 8%.

“Machine learning is an application of artificial intelligence where systems automatically learn and improve from experience without being explicitly programmed,” said Emmanuel Ifeachor, Principal Investigator Professor from the School of Computing Electronics and Mathematics at the University of Plymouth. “It’s already being used for many applications throughout healthcare such as medical imaging, but using it for patient data has not been done in quite this way before. The methodology is promising and, if successfully developed and deployed, may help to increase dementia diagnosis in primary care.”

“Dementia is a disease with so many different contributing factors, and it can be quite difficult to pinpoint or predict,” said Dr. Camille Carroll, Consultant Neurologist at University Hospitals Plymouth NHS Trust and Researcher in the Institute of Translational and Stratified Medicine at the University of Plymouth. “There is strong epidemiological evidence that a number of cardiovascular and lifestyle factors such as hypertension; high cholesterol; diabetes; obesity; stroke; atrial fibrillation; smoking; and reduced cognitive, physical, or social activities can predict the risk of dementia in later life, but no studies have taken place that allow us to see this quickly. So having tools that can take a vast amount of data, and automatically identify patients with possible dementia, to facilitate targeted screening, could potentially be very useful and help improve diagnosis rates.”

Related Links:
University of Plymouth
National Health Service

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70 (372.88665771484): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294774648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (245.09429931641): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294774648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (118.97087097168): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (458.0020904541): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (124.93133544922): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (183.8207244873): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (522.13668823242): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (65.088272094727): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (!!!!! 1364.9463653564): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294774648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (66.995620727539): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294774648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (47.922134399414): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 1698.0171203613): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (66.995620727539): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (84.877014160156): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (111.10305786133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

105 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

106 (76.055526733398): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294774648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (68.187713623047): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294774648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 2830.982208252): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

109 (137.0906829834): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

110 (71.048736572266): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294774648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 10599.136352539): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294774648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (746.9654083252): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (564.0983581543): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (136.13700866699): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

115 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

116 (92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

117 (68.187713623047): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

118 (84.877014160156): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

119 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

120 (436.06758117676): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 180562.01934814): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (163.07830810547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

123 (81.062316894531): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

124 (!!!!! 1192.0928955078): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294774648 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294774648 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 2860216.1407471): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (!!!!! 1109430.0746918): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (69.856643676758): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (116.10984802246): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (59.127807617188): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (30.040740966797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (27.894973754883): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (27.894973754883): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (473.97613525391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (374.07875061035): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (36.954879760742): SELECT name FROM jos_deeppockets WHERE id=217

136 (29.087066650391): SELECT name FROM jos_deeppockets WHERE id=217

137 (569.10514831543): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))217((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (384.09233093262): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))217((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (!!!!! 1010.1795196533): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

140 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

141 (!!!!! 8190.8702850342): TRUNCATE TABLE jos_trademed_module

142 (162.83988952637): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294774648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (627.99453735352): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294774648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (411.9873046875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

147 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

148 (!!!!! 1171.8273162842): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

150 (56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

151 (420.80879211426): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294774648 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294774648 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (51.975250244141): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=217 or channel_id is null)

153 (32.186508178711): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=217 or channel_id is null)

154 (40.054321289062): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

156 (114.20249938965): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294774648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294774648 AND published='1' LIMIT 1

157 (46.968460083008): select jos_twitters.link from jos_twitters where cat=10

158 (83.208084106445): select jos_facebook.link from jos_facebook where cat=10

159 (77.962875366211): select jos_google_plus.link from jos_google_plus where cat=10

160 (39.100646972656): select jos_linkedin.link from jos_linkedin where cat=10

161 (319.9577331543): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 1574.9931335449): insert into jos_banners_delta values (14615,'2025-06-18 03:01:54','216.73.216.120','view'),(14202,'2025-06-18 03:01:54','216.73.216.120','view'),(14203,'2025-06-18 03:01:54','216.73.216.120','view')

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