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Alliance to Develop Optical Imaging for Breast Cancer

By HospiMedica staff writers
Posted on 19 Dec 2005

Philips Medical Systems (Best, The Netherlands) and pharmaceutical company Schering AG (Berlin, Germany) have formed a collaboration to research, develop, and market medical equipment and associated contrast agents for optical imaging. More...

As part of their collaboration, the companies will have the option to expand the alliance to cover other imaging technologies and contrast agents, where synergies between the partners are expected, and will also explore the emerging field of molecular imaging. Philips and Schering have agreed to split equally all research and development costs as well as all future revenues. Financial details of the alliance were not disclosed.

Optical imaging is a new imaging modality with the potential to provide new applications in the prevention and treatment of breast cancer as well as other diseases. Optical imaging uses lasers to illuminate superficial tissue--such as breast tissue. By combining this technology with an optical dye, tumors might be targeted more accurately. Because of its high resolution and sensitivity, optical imaging is predicted to provide breast cancer patients with a less-aggressive, more patient-friendly follow-up screening. Currently, such patients may need to undergo the invasive procedure of a biopsy in cases where conventional exams produce uncertain results.

"Schering is highly committed to drive innovation in the field of optical imaging,” said Dr. Karin Dorrepaal, member of the executive board of Schering AG, responsible for diagnostic imaging. "We are looking forward to combining our expertise in the field of optical imaging agents with Philips' strong capabilities in medical imaging and established track record in developing leading edge diagnostic imaging.”

The alliance's first development project will combine an optical dye called omocianine (SF-64) from Schering for the diagnosis of breast cancer, currently in phase I trials, with an enhanced mammography device developed by Philips. The companies will also explore the emerging field of molecular imaging, looking at how to develop dyes that can potentially target breast tumors at the molecular level. It is estimated that once products are commercialized, the market for optical imaging contrast agents and equipment will see average annual growth rates of over 20%.

Related Links:
Philips Medical Systems
Schering

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59 (782.01293945312): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=170670000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

60 (!!!!! 1256.9427490234): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

61 (95.129013061523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

62 (146.86584472656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

63 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

64 (127.07710266113): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

65 (499.01008605957): SELECT fid FROM jos_deeppockets WHERE id=170670000 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=170670000 AND published='1' LIMIT 1

66 (45.061111450195): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=217 ORDER BY `ordering`

67 (41.007995605469): select jos_twitters.link from jos_twitters where cat=10

68 (30.040740966797): select jos_facebook.link from jos_facebook where cat=10

69 (31.948089599609): select jos_google_plus.link from jos_google_plus where cat=10

70 (28.848648071289): select jos_linkedin.link from jos_linkedin where cat=10

71 (30.994415283203): SELECT fid FROM jos_deeppockets WHERE id=170670000 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=170670000 AND published='1' LIMIT 1

72 (30.994415283203): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=217 ORDER BY `ordering`

73 (358.10470581055): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=170670000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

74 (257.01522827148): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=170670000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

75 (40.054321289062): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

76 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (46.968460083008): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=170670000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

91 (30.994415283203): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=170670000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

92 (32.901763916016): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

93 (65.803527832031): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

107 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

108 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

109 (61.03515625): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=170670000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

110 (45.061111450195): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=170670000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

112 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

113 (360.01205444336): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=170670000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

114 (344.99168395996): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=170670000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

115 (51.021575927734): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=170660000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

116 (366.2109375): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=170660000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

117 (574.82719421387): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

118 (367.87986755371): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

119 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

120 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

121 (43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

122 (35.04753112793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

123 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

124 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

125 (39.815902709961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

126 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

127 (281.09550476074): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

128 (!!!!! 19714.832305908): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

129 (496.86431884766): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=170670000 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=170670000 AND type='deeppockets_item' AND published='1' LIMIT 1

130 (58.174133300781): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

131 (36.001205444336): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

132 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

133 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

134 (37.908554077148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

135 (30.040740966797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

136 (28.133392333984): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

137 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

138 (30.040740966797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

139 (27.894973754883): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

140 (468.96934509277): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

141 (339.98489379883): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

142 (41.961669921875): SELECT name FROM jos_deeppockets WHERE id=217

143 (33.140182495117): SELECT name FROM jos_deeppockets WHERE id=217

144 (556.94580078125): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))217((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

145 (433.92181396484): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))217((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

146 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

147 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

148 (!!!!! 8270.9789276123): TRUNCATE TABLE jos_trademed_module

149 (123.02398681641): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=170670000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

150 (66.995620727539): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=170670000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

151 (905.99060058594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

152 (99.897384643555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

153 (85.115432739258): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

154 (84.161758422852): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

155 (!!!!! 1362.0853424072): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

156 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

157 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

158 (47.922134399414): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=170670000 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=170670000 AND type='deeppockets_item' AND published='1' LIMIT 1

159 (42.915344238281): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

160 (36.001205444336): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

161 (67.949295043945): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

162 (483.98971557617): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

163 (175.95291137695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=170670000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=170670000 AND published='1' LIMIT 1

164 (56.982040405273): select jos_twitters.link from jos_twitters where cat=10

165 (41.007995605469): select jos_facebook.link from jos_facebook where cat=10

166 (35.04753112793): select jos_google_plus.link from jos_google_plus where cat=10

167 (37.908554077148): select jos_linkedin.link from jos_linkedin where cat=10

168 (315.18936157227): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14202,14203)

169 (944.13757324219): insert into jos_banners_delta values (14202,'2025-08-20 00:20:22','216.73.216.0','view'),(14203,'2025-08-20 00:20:22','216.73.216.0','view')

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