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Imaging Data, Tools Developed for Heart Disease Research

By MedImaging International staff writers
Posted on 25 Nov 2014

A virtual machine is being developed to optimize reproducibility and data availability to assess and enhance analyses of magnetic resonance imaging (MRI) myocardial perfusion data.

The project was described November 11, 2014, in the open access, open data journal GigaScience. More...

The study’s researchers, from the Universidad Politécnica de Madrid (Spain) and the US National Institutes of Health (Bethesda, MD, USA) provide an excellent example of open data sharing to help build these exact tools: an abundance of patient imaging data. To enable reproducible comparisons between new tools, the researchers and the journal are publishing and packaging the data combined with tools, scripts, and the software required to conduct the research. This is available for download from GigaScience’s GigaDB database as a “virtual hard disk” that will specifically allow researchers to directly run the experiments themselves and to add their own annotations to the data set.

The most typical cause of heart attacks is coronary heart disease. Diagnosis is vital to beginning treatment for preventing such events. One useful tool in the fight against this leading killer is MRI, which allows the direct examination of blood flow to the myocardium of the heart. However, for this perfusion analysis technique to be the most effective requires compensation for the breathing motion of the patient, which is done using complex image processing methods. Therefore, there is a need to improve these tools and algorithms. The key to achieving things is the availability of large publicly available MRI datasets to allow testing, optimization and development of new methods.

As one potential user of these resources, Prof. Alistair Young, technical director of the Auckland Magnetic Resonance Research Group (New Zealand), commented, “Very large amounts of medical imaging data are now becoming available through registries and large population studies. Well-validated, automated methods are required to derive maximum benefit from such resources. The paper by Wollny and Kellman exemplifies how data and algorithm sharing can advance the field by providing a platform by which existing methods can be tested and new methods validated against existing benchmarks. Such benchmarking datasets are essential to advance the field through objective metrics and standards.”

Having everything compiled in a virtual machine also made things easier during the scientific peer-review and publication process, because the settings, packages, and file locations were already set up in a working configuration. One of the people performing this testing process, Dr. Robert Davidson, a data scientist at GigaScience, stated, “Actually testing the code during review is sadly almost a novel concept and one that needs to roll out as a standard. But even more: if it's easy for the reviewers, it’s easy for the community to use too.”

As well as being important for improving the diagnosis for the number one cause of death worldwide, the continuing upsurge in retractions of published scientific articles, makes the addition of direct means to improve article reproducibility is essential, both for the ability to be able to believe in the current findings, on which future studies are built, and to prevent the public losing conviction in the research community they fund. Publishing a virtual machine, an interactive and executable publication provides an example to the scientific community and test case demonstrating a potential new type of scholarly yield, according to the investigators.

Related Links:
Universidad Politécnica de Madrid
US National Institutes of Health

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57 (!!!!! 4601.001739502): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755901 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

58 (!!!!! 1878.9768218994): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

59 (98.943710327148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

60 (180.00602722168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

61 (173.09188842773): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

62 (123.02398681641): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

63 (592.94700622559): SELECT fid FROM jos_deeppockets WHERE id=294755901 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294755901 AND published='1' LIMIT 1

64 (61.988830566406): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=216 ORDER BY `ordering`

65 (78.916549682617): select jos_twitters.link from jos_twitters where cat=10

66 (33.855438232422): select jos_facebook.link from jos_facebook where cat=10

67 (43.153762817383): select jos_google_plus.link from jos_google_plus where cat=10

68 (30.040740966797): select jos_linkedin.link from jos_linkedin where cat=10

69 (36.001205444336): SELECT fid FROM jos_deeppockets WHERE id=294755901 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294755901 AND published='1' LIMIT 1

70 (68.902969360352): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=216 ORDER BY `ordering`

71 (572.20458984375): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755901 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (391.96014404297): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755901 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (65.088272094727): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

74 (88.930130004883): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (57.93571472168): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (82.015991210938): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755901 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (46.014785766602): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755901 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (48.87580871582): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

91 (76.055526733398): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (55.074691772461): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (49.114227294922): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (71.048736572266): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (52.213668823242): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (115.87142944336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

106 (69.856643676758): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

107 (82.969665527344): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755901 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (68.902969360352): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755901 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (126.83868408203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

110 (87.02278137207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

111 (79.154968261719): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294755901 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (773.19145202637): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294755901 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (849.00856018066): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (442.0280456543): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (202.89421081543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

116 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

117 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

118 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

119 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

120 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

121 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

122 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

123 (381.9465637207): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

124 (!!!!! 30936.002731323): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

125 (!!!!! 1519.2031860352): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755901 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755901 AND type='deeppockets_item' AND published='1' LIMIT 1

126 (!!!!! 22349.119186401): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (76.055526733398): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (472.7840423584): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (47.922134399414): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (31.948089599609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (298.02322387695): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (37.193298339844): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (36.001205444336): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (31.948089599609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (404.83474731445): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (917.91152954102): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (!!!!! 4967.9279327393): SELECT name FROM jos_deeppockets WHERE id=216

139 (!!!!! 1868.0095672607): SELECT name FROM jos_deeppockets WHERE id=216

140 (890.97023010254): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (825.16670227051): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (687.1223449707): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

143 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

144 (!!!!! 7019.04296875): TRUNCATE TABLE jos_trademed_module

145 (!!!!! 3340.0058746338): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755901 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (138.99803161621): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755901 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (445.12748718262): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (195.02639770508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (93.936920166016): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

150 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

151 (!!!!! 1675.8441925049): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

152 (124.93133544922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

153 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

154 (39.100646972656): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755901 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755901 AND type='deeppockets_item' AND published='1' LIMIT 1

155 (30.040740966797): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=216 or channel_id is null)

156 (34.809112548828): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=216 or channel_id is null)

157 (48.160552978516): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

158 (88.930130004883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

159 (82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755901 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755901 AND published='1' LIMIT 1

160 (180.95970153809): select jos_twitters.link from jos_twitters where cat=10

161 (230.07392883301): select jos_facebook.link from jos_facebook where cat=10

162 (437.02125549316): select jos_google_plus.link from jos_google_plus where cat=10

163 (!!!!! 1251.9359588623): select jos_linkedin.link from jos_linkedin where cat=10

164 (!!!!! 1049.9954223633): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14202,14203)

165 (!!!!! 5373.0010986328): insert into jos_banners_delta values (14202,'2025-08-04 13:33:03','216.73.216.210','view'),(14203,'2025-08-04 13:33:03','216.73.216.210','view')

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