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Faster Treatment Choices for Bowel-Cancer Patients Using Tumor-Imaging Analysis Technology

By MedImaging International staff writers
Posted on 25 Nov 2014

New imaging analysis technology helps hospitals make earlier and more accurate treatment decisions and survival assessments for patients with bowel cancer. More...

An innovative new medical imaging technology, TexRAD (Cambridge, UK), is an imaging risk stratification tool that analyses the texture of clinical diagnostic images for prognosis, risk, and treatment response. The tool analyses the texture of tumors, and has been shown in trials to enable early diagnosis of bowel-cancer patients not responding to the standard cancer therapy comparably better than other available tumor markers. Furthermore, the TexRAD markers showed the ability to evaluate at an early stage the probability of survival, differentiating patients who will have a good prognosis from those having poor prognosis.

Dr. Balaji Ganeshan, one of the University of Sussex (Brighton, UK) researchers whose research led to the development of the technology, said, “By using TexRAD to scan for subtle anomalies in a tumor’s texture, researchers have been able to spot more quickly when treatments are or are not working and adjust treatment accordingly. And because TexRAD simply provides an additional layer of software analysis of the MRI [magnetic resonance imaging] and CT [computed tomography] scans that already exist as part of routine clinical practice, it is noninvasive from the patient’s point of view and potentially cost-effective to the healthcare provider.”

The technology is being evaluated in a number of research institutions and university hospitals worldwide. Across two separate UK studies, researchers analyzed the tumors of 155 bowel-cancer patients. In a study at University College London Hospitals (UK), researchers examined baseline PET [positron emission tomography]-CT scans, i.e., those taken before treatment, and then followed up with the patients for an average of three years later. They found that analyzing the texture of the tumors in the first scans enabled them to effectively predict patient survival.

At Colchester General Hospital (UK), the researchers searched through MR scans captured both before treatment and six weeks after the patients had completed chemotherapy and radiotherapy, and found that the patients whose tumors were less heterogeneous (more uniform) in terms of texture parameters six weeks after treatment were more likely to survive longer.

Furthermore, researchers from the University of Rome (Italy) revealed that texture analysis provides useful imaging biomarkers that indicate how the tumor is responding to chemotherapy and radiotherapy. Andrea Laghi, a professor of radiology at the University of Rome, and lead investigator of the study, said, “The identification of new, accurate imaging biomarkers such as TexRAD analysis of MR images for early assessment of first-line cancer therapy response [predominantly to shrink the tumor before the main treatment] could be helpful in refining bowel-cancer patient management, providing a better targeting of preoperative therapy.”

The findings of the three studies will be presented to a wide international audience of radiologists, imaging scientists, healthcare providers, and industry at the 100th annual scientific meeting and exhibition of the Radiological Society of North America (RSNA), which will take place in Chicago (IL, USA), from November 30–December 5, 2014.

Related Links:
University of Sussex
University College London Hospitals
TexRAD

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58 (!!!!! 1463.8900756836): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

59 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

60 (113.01040649414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

61 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

62 (179.05235290527): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

63 (648.97537231445): SELECT fid FROM jos_deeppockets WHERE id=294755900 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294755900 AND published='1' LIMIT 1

64 (344.99168395996): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=216 ORDER BY `ordering`

65 (!!!!! 1296.9970703125): select jos_twitters.link from jos_twitters where cat=10

66 (66.041946411133): select jos_facebook.link from jos_facebook where cat=10

67 (36.954879760742): select jos_google_plus.link from jos_google_plus where cat=10

68 (29.802322387695): select jos_linkedin.link from jos_linkedin where cat=10

69 (41.007995605469): SELECT fid FROM jos_deeppockets WHERE id=294755900 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294755900 AND published='1' LIMIT 1

70 (42.915344238281): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=216 ORDER BY `ordering`

71 (436.78283691406): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755900 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (309.94415283203): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755900 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (43.869018554688): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

74 (76.055526733398): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (51.021575927734): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755900 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (30.994415283203): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755900 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (35.04753112793): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

91 (84.877014160156): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (!!!!! 2442.1215057373): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (91.075897216797): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (42.200088500977): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (195.98007202148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

106 (63.180923461914): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

107 (59.843063354492): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755900 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (633.00132751465): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755900 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (112.05673217773): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

110 (56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

111 (61.03515625): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294755900 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (643.01490783691): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294755900 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (514.03045654297): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (328.06396484375): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

116 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

117 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

118 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

119 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

120 (35.04753112793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

121 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

122 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

123 (318.05038452148): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

124 (!!!!! 63668.012619019): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

125 (566.00570678711): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755900 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755900 AND type='deeppockets_item' AND published='1' LIMIT 1

126 (!!!!! 19151.926040649): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (152.1110534668): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (97.036361694336): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (65.803527832031): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (70.095062255859): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (43.869018554688): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (521.89826965332): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (152.1110534668): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (51.021575927734): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (40.769577026367): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (486.13548278809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (352.14424133301): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (169.99244689941): SELECT name FROM jos_deeppockets WHERE id=216

139 (39.100646972656): SELECT name FROM jos_deeppockets WHERE id=216

140 (744.81964111328): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (647.06802368164): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

143 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

144 (!!!!! 7447.0043182373): TRUNCATE TABLE jos_trademed_module

145 (!!!!! 6389.1410827637): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755900 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (185.01281738281): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294755900 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (453.94897460938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (164.98565673828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (64.13459777832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

150 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

151 (!!!!! 1614.0937805176): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

152 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

153 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

154 (49.114227294922): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294755900 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294755900 AND type='deeppockets_item' AND published='1' LIMIT 1

155 (35.04753112793): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=216 or channel_id is null)

156 (28.848648071289): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=216 or channel_id is null)

157 (34.093856811523): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

158 (104.18891906738): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

159 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294755900 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294755900 AND published='1' LIMIT 1

160 (182.8670501709): select jos_twitters.link from jos_twitters where cat=10

161 (41.007995605469): select jos_facebook.link from jos_facebook where cat=10

162 (!!!!! 2115.9648895264): select jos_google_plus.link from jos_google_plus where cat=10

163 (96.08268737793): select jos_linkedin.link from jos_linkedin where cat=10

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