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Bone Suppression Software with Chest X-Ray Equivalent to Dual Energy Subtraction Imaging in the Detection of Potential Lung Cancer

By MedImaging International staff writers
Posted on 05 Jul 2012

New software considerably enhances the radiologists’ ability to detect potentially cancerous lung nodules in X-ray images, and may become a cost-effective option to dual energy subtraction (DES) imaging, according to two new studies.

The studies’ findings were presented at the 20th anniversary meeting of the European Society of Thoracic Imaging (ESTI), June 22-24, 2012, in London (UK). Riverain Technologies’ (Dayton, OH, USA) ClearRead bone suppression software utilizes machine learning algorithms to convert any conventional chest X-ray image into an enhanced, soft tissue image without the ribs and clavicles that sometimes obscure early lung cancer. DES also creates a soft tissue image but requires a dedicated dual energy imaging system to form it.

Depending on the methodology, DES may require two separate scans, thereby exposing patients to more radiation than conventional X-ray. Riverain’s computer-aided detection (CAD) software, ClearRead +Detect, provides additional support in decision making by circling suspicious areas on a bone-suppressed image that may be lung cancer. Final determination is made by the radiologist.

The first study, conducted at the Institute of Diagnostic, Interventional and Pediatric Radiology at the University Hospital Bern (Switzerland), compared Riverain’s bone suppression and DES alone and in combination with CAD and revealed that the bone suppression software is as good as DES at detecting lung nodules while producing superior image quality.

In the retrospective study, three radiologists independently reviewed chest images of 143 patients: 101 patients with 155 lung nodules between 5-29 mm earlier validated using CT, and 42 subjects with no lung nodules. Each radiologist tagged suspected nodules on each patient’s original chest X-ray image, and individually on DES and bone-suppressed images with and without CAD.

The radiologists detected the most lung nodules in the bone-suppressed image with CAD markings. Their mean sensitivities--the percentage of the 155 lung nodules that were accurately identified--were: 46.9% using traditional X-ray only; 49.2% using a single-shot DES system; 49.7% using SoftView 2.0 (an earlier version of Riverain’s ClearRead bone suppression); and 51.6% using SoftView 2.0 plus OnGuard 5.1 (an earlier version Riverain’s ClearRead +Detect software). The overall diagnostic performance with the modalities was not significantly different.
“These findings are compelling results for hospitals, radiology practices and patients,” said Steve Worrell, Riverain’s chief technology officer. “Radiologists detected as many lung nodules using Riverain bone suppression software on conventional X-ray images as they detected using a dedicated piece of imaging equipment that is more expensive, may expose patients to more radiation, and can only be used in the single location where it is housed. Our software immediately enhances any standard chest X-ray image, after capture, and can be used throughout entire healthcare systems without additional imaging equipment, staff or space requirements, and without any additional tests or radiation dose for patients.”

The radiologists also gave the bone-suppressed images a significantly higher overall quality rating than the DES images. The true-positive and false-positive rates of these two modalities were statistically equivalent. “Electronic bone suppression provides equivalent detection rates for lung nodules as DES, with better image quality, and might be a cost-effective alternative to DES chest radiography in the detection of lung nodules,” said Zsolt Szucs-Farkas, MD, PhD, chief investigator.

Dr. Szucs-Farkas also compared CAD markings before radiologist interpretation to the radiologists’ findings. Whereas CAD and the radiologists detected many of the same lung nodules, each also detected nodules the other did not find. CAD, on its own without any radiologist interpretation (evaluated for research purposes only), accurately circled approximately one in four nodules that the radiologists missed, and the radiologists found approximately one in three nodules that CAD missed.

“Working together, radiologists and our CAD with bone suppression software bring different strengths to the table and significantly improve the detection of nodules that may be lung cancer using conventional chest X-ray,” Dr. Worrell said.

A second study presented at ESTI 2012 also confirmed Riverain’s bone suppression software considerably improves radiologists’ ability to detect lung nodules in chest X-ray images. Eight radiologists from the Radboud University Nijmegen Medical Center (RUNMC; The Netherlands) and the Meander Medical Center (Amersfoort, The Netherlands), reviewed chest X-ray images for 108 patients with only one CT-proven lung nodule and 192 patients without nodules. On average, they found 14.4% of lung nodules using Riverain’s bone suppression technology (SoftView 2.4, now called ClearRead bone suppression) that were missed when they used conventional X-ray alone, without an increase in false-positives. All individual readers improved detection with the help of the bone suppression software. Individual reader results ranged from as low as 52% without bone suppression to a high of 81% with the software. Average detection overall was 67% using X-ray alone, and 72% with bone suppression software.

Riverain Technologies applies proprietary pattern recognition and machine-learning technologies in the creation of software applications for use globally in the healthcare industry. The company’s ClearRead software increases the expert skills of radiologists to improve patient outcomes using standard chest X-ray, without additional radiation dose or procedures for patients.

Related Links:
Riverain Technologies
Radboud University Nijmegen Medical Center
Meander Medical Center

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56 (578.88031005859): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294741424 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

57 (!!!!! 1516.1037445068): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

58 (!!!!! 1167.0589447021): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

59 (!!!!! 1426.9351959229): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

60 (111.81831359863): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

61 (!!!!! 5299.0913391113): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (523.09036254883): SELECT fid FROM jos_deeppockets WHERE id=294741424 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294741424 AND published='1' LIMIT 1

63 (403.16581726074): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=216 ORDER BY `ordering`

64 (80.108642578125): select jos_twitters.link from jos_twitters where cat=10

65 (41.961669921875): select jos_facebook.link from jos_facebook where cat=10

66 (55.074691772461): select jos_google_plus.link from jos_google_plus where cat=10

67 (40.054321289062): select jos_linkedin.link from jos_linkedin where cat=10

68 (59.127807617188): SELECT fid FROM jos_deeppockets WHERE id=294741424 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294741424 AND published='1' LIMIT 1

69 (46.014785766602): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=216 ORDER BY `ordering`

70 (241.04118347168): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294741424 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (356.19735717773): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294741424 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (59.127807617188): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (77.009201049805): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (60.081481933594): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (89.168548583984): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (67.949295043945): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (55.074691772461): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (74.863433837891): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (65.088272094727): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (59.127807617188): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (321.1498260498): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294741424 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (59.843063354492): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294741424 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (56.028366088867): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (406.98051452637): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (92.029571533203): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (85.830688476562): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (64.849853515625): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (74.148178100586): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (92.983245849609): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (102.99682617188): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (77.962875366211): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (652.07481384277): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

105 (94.175338745117): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

106 (62.942504882812): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294741424 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (50.067901611328): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294741424 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 1285.0761413574): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

109 (98.943710327148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

110 (93.936920166016): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294741424 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (471.11511230469): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294741424 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (669.95620727539): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (376.93977355957): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

115 (55.789947509766): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

116 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

117 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

118 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

119 (39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

120 (284.91020202637): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 95499.992370605): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (549.0779876709): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

123 (591.03965759277): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

124 (!!!!! 7008.0757141113): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294741424 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294741424 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 1786787.0330811): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (!!!!! 933330.05905151): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (70.095062255859): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (42.915344238281): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (30.994415283203): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (28.133392333984): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (27.179718017578): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (466.10832214355): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (522.13668823242): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (221.01402282715): SELECT name FROM jos_deeppockets WHERE id=216

136 (35.04753112793): SELECT name FROM jos_deeppockets WHERE id=216

137 (446.79641723633): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (368.11828613281): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (!!!!! 1160.1448059082): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

140 (56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

141 (!!!!! 9987.8311157227): TRUNCATE TABLE jos_trademed_module

142 (108.00361633301): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294741424 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (563.8599395752): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294741424 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (504.0168762207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

147 (63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

148 (!!!!! 1324.1767883301): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

150 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

151 (813.00735473633): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294741424 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294741424 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (622.98774719238): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=216 or channel_id is null)

153 (46.014785766602): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=216 or channel_id is null)

154 (61.988830566406): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (!!!!! 3317.11769104): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

156 (64.13459777832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741424 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741424 AND published='1' LIMIT 1

157 (66.041946411133): select jos_twitters.link from jos_twitters where cat=10

158 (27.894973754883): select jos_facebook.link from jos_facebook where cat=10

159 (29.087066650391): select jos_google_plus.link from jos_google_plus where cat=10

160 (33.855438232422): select jos_linkedin.link from jos_linkedin where cat=10

161 (293.97010803223): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 1537.0845794678): insert into jos_banners_delta values (14615,'2025-06-19 03:20:49','216.73.216.120','view'),(14202,'2025-06-19 03:20:49','216.73.216.120','view'),(14203,'2025-06-19 03:20:49','216.73.216.120','view')

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