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IT May Transform World Healthcare

By MedImaging International staff writers
Posted on 09 Aug 2011

An enormous network of computer programs could revolutionize healthcare around the world, saving myriad lives and billions of dollars.

Working with a number of partners, the academics have been awarded funds from a huge European research program to create “virtual patients”--computational models of individual people--which could lead to everyone having their own individually customized health system based on their genetic and physiologic make-up.

Under the system, physicians would be able to have an instant, in-depth knowledge of an individual patient’s health needs and medical history available readily. This will allow general practitioners (GPs) to diagnose accurately and rapidly illnesses and conditions, saving patients from potentially deadly side effects of incorrectly prescribed medicines and saving huge amounts of money on drugs.

The University of Manchester (UK) researchers are part of a pan-European, 10-year project, called IT Future of Medicine (ITFoM), costing EUR 1 billion. ITFOM has been allocated EUR 1.5 million preliminary funding. A consortium of more than 25 academic institutions and industrial partners with expertise in information and communications technology (ICT), the life sciences, public health, and medicine have come together to begin the process of bringing the project to life.

As it progresses, even more partners will come on board, ultimately making this one of the largest collaborative endeavors since the Apollo space program. A vast range of ICT developments must take place in order to make this medicine of the future a reality. This will include new techniques for the rapid acquisition and evaluation of patient data, dynamic storage and processing of real time patient data into relevant mathematical models, and the development of new systems that can learn, predict and inform. These are needed to provide healthcare professionals and patients with unprecedented insights into matters of health and treatment.

The first goal is to give each GP the power to use a person’s individual genome to inform every stage of disease management--through diagnosis, treatment, and follow-up. This will require a transformation in ICT technologies so that relevant computing, storage, networking, and modeling technologies are developed. The IT systems will create mathematical models using vast amounts of data--knowledge to date about how humans work.

ITFoM will also provide scenarios, such as what would happen if a patient takes a specific drug, what would happen if they started running three times a week? Through the gathered genome sequencing and clinical data, the general model will be able to be adapted to suit the particular health demands of any individual, including such issues as allergies, congenital defects, and current treatment. ITFoM was set up as it was believed that, whereas IT and computing played a large role in many commercial scientific areas, its potential power to revolutionize medicine has not yet been realized.

Prof. Hans Westerhoff, who is leading the Manchester part of the project, believes computer models will essentially change the way healthcare is provided. He added, “ITFoM will make general models of human pathways, tissues, diseases, and ultimately of the human as a whole. These models will then be used to identify personalized prevention and therapy schedules, and the side effects of drugs. The models will be there to help diagnose a particular problem and provide solutions. Obviously, this would need to be done in conjunction with a person’s GP depending on the gravity of the situation. Making personalized medicine a reality will thus require fundamental advances in the computational sciences. It promises to be unique and groundbreaking because people could access their own health model. It is intended to be a large, straightforward system, which can also inform treatment regimes. This is the first time that huge IT systems looking at individual care will be combined with genomics and medical needs.”

Prof. Norman Paton, head of the School of Computer Science, added, “The IT Future of Medicine project provides an exciting opportunity to bring together and build upon advances in medical, biological and computational sciences. “The greatest opportunities to improve outcomes in medicine seem likely to come from personalized medicine, the biological sciences are providing the insights required to support informed personalization, and advanced computational techniques are essential for making sense of the data that informs decision making. This is a fantastic opportunity to bring together advances from these three rapidly developing areas to bring about a paradigm shift in medical practice.”

ITFoM is one of six pilot projects in the European Future and Emerging Technologies flagship scheme. These projects are vying for EUR 1 billion funding over 10 years to in order to generate a scientific revolution. The finalists are:
1. FuturICT Knowledge Accelerator and Crisis-Relief System: ICT can analyze vast amounts of data and complex situations so as to better predict natural disasters, or manage and respond to man-made disasters that cross national borders or continents.
2. Graphene Science and Technology for ICT and Beyond: Graphene is a new substance developed by atomic and molecular scale manipulation that could replace silicon as the wonder material of the 21st century.
3. Guardian Angels for a Smarter Life: tiny devices without batteries that act like autonomous personal assistants, and which can sense, compute, and communicate potentially even while travelling through the bloodstream.
4. The Human Brain Project: understanding the way in which the human brain works can bring the benefits of brain-related or brain-inspired developments to computing architectures, neuroscience and medicine.
5. IT Future of Medicine: digital technology has the power to deliver individualized medicine, based on molecular, physiologic, and anatomic data collected from individual patients and processed on the basis of globally integrated medical knowledge.
6. Robot Companions for Citizens: soft skinned and intelligent robots have highly developed perceptive and emotional skills, and can help people, radically changing the way humans interact with machines.

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56 (495.19538879395): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294736505 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

57 (!!!!! 1566.1716461182): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

58 (729.79927062988): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

59 (542.87910461426): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

60 (582.93342590332): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

61 (!!!!! 2582.7884674072): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (874.99618530273): SELECT fid FROM jos_deeppockets WHERE id=294736505 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294736505 AND published='1' LIMIT 1

63 (!!!!! 1156.0916900635): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=216 ORDER BY `ordering`

64 (416.04042053223): select jos_twitters.link from jos_twitters where cat=10

65 (375.03242492676): select jos_facebook.link from jos_facebook where cat=10

66 (210.04676818848): select jos_google_plus.link from jos_google_plus where cat=10

67 (172.13821411133): select jos_linkedin.link from jos_linkedin where cat=10

68 (272.03559875488): SELECT fid FROM jos_deeppockets WHERE id=294736505 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294736505 AND published='1' LIMIT 1

69 (171.89979553223): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=216 ORDER BY `ordering`

70 (463.96255493164): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294736505 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (257.96890258789): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294736505 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (182.15179443359): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (837.08763122559): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (212.19253540039): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (234.12704467773): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (155.92575073242): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (271.08192443848): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (106.0962677002): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (153.0647277832): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (109.19570922852): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (138.99803161621): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (108.95729064941): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (133.03756713867): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (108.00361633301): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (131.13021850586): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (110.14938354492): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (749.11117553711): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294736505 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (544.07119750977): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294736505 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (206.94732666016): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (121.8318939209): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (226.02081298828): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 3296.1368560791): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

105 (604.86793518066): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

106 (63.896179199219): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294736505 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (47.922134399414): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294736505 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (182.15179443359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

109 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

110 (56.028366088867): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294736505 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (323.05717468262): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294736505 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (542.87910461426): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (363.82675170898): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

115 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

116 (97.990036010742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

117 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

118 (107.0499420166): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

119 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

120 (229.83551025391): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 128008.84246826): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (!!!!! 7778.8829803467): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

123 (!!!!! 7992.9828643799): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

124 (!!!!! 8330.1067352295): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294736505 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294736505 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 1270569.0860748): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (154.97207641602): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (133.03756713867): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (173.09188842773): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (221.96769714355): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (144.00482177734): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (125.16975402832): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (125.88500976562): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (!!!!! 2287.1494293213): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (562.90626525879): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (388.14544677734): SELECT name FROM jos_deeppockets WHERE id=216

136 (154.97207641602): SELECT name FROM jos_deeppockets WHERE id=216

137 (633.00132751465): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (752.92587280273): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (315.90461730957): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

140 (133.99124145508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

141 (!!!!! 8716.8216705322): TRUNCATE TABLE jos_trademed_module

142 (287.05596923828): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294736505 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (65.803527832031): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294736505 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (848.05488586426): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

147 (171.18453979492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

148 (!!!!! 7213.1156921387): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (!!!!! 2867.9370880127): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

150 (!!!!! 1601.9344329834): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

151 (46.014785766602): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294736505 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294736505 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (35.04753112793): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=216 or channel_id is null)

153 (30.040740966797): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=216 or channel_id is null)

154 (30.994415283203): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

156 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736505 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736505 AND published='1' LIMIT 1

157 (320.9114074707): select jos_twitters.link from jos_twitters where cat=10

158 (34.093856811523): select jos_facebook.link from jos_facebook where cat=10

159 (266.07513427734): select jos_google_plus.link from jos_google_plus where cat=10

160 (47.922134399414): select jos_linkedin.link from jos_linkedin where cat=10

161 (350.9521484375): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 1354.2175292969): insert into jos_banners_delta values (14615,'2025-06-19 13:09:48','216.73.216.120','view'),(14202,'2025-06-19 13:09:48','216.73.216.120','view'),(14203,'2025-06-19 13:09:48','216.73.216.120','view')

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