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Artificial Intelligence (AI) Tool Detects Pancreatic Cancer on CT

By MedImaging International staff writers
Posted on 14 Sep 2022

Image: A new deep learning AI tool is effective at identifying pancreatic cancer on CT (Photo courtesy of Pexels)

Pancreatic cancer has the lowest five-year survival rate among cancers. It is projected to become the second leading cause of cancer death in the U.S. by 2030. Early detection is the best way to improve the dismal outlook, as prognosis worsens significantly once the tumor grows beyond two centimeters. Computed tomography (CT) is the key imaging method for detection of pancreatic cancer, but it misses about 40% of tumors under two centimeters. There is an urgent need for an effective tool to help radiologists in improving pancreatic cancer detection. Now, a new study has found an artificial intelligence (AI) tool to be highly effective at detecting pancreatic cancer on CT.

Researchers at the National Taiwan University (Taipei, Taiwan) have been studying a computer-aided detection (CAD) tool that uses a type of AI called deep learning to detect pancreatic cancer. They previously showed that the tool could accurately distinguish pancreatic cancer from noncancerous pancreas. However, that study relied on radiologists manually identifying the pancreas on imaging - a labor-intensive process known as segmentation. In the new study, the AI tool identified the pancreas automatically. This is an important advance considering that the pancreas borders multiple organs and structures and varies widely in shape and size.

The researchers developed the tool with an internal test set consisting of 546 patients with pancreatic cancer and 733 control participants. The tool achieved 90% sensitivity and 96% specificity in the internal test set. Validation followed with a set of 1,473 individual CT exams from institutions throughout Taiwan. The tool achieved 90% sensitivity and 93% specificity in distinguishing pancreatic cancer from controls in that set. Sensitivity for detecting pancreatic cancers less than two centimeters was 75%. The CAD tool has the potential to provide a wealth of information to assist clinicians, according to the researchers and could indicate the region of suspicion to speed radiologist interpretation. The researchers are planning further studies. In particular, they want to look at the tool's performance in more diverse populations. Since the current study was retrospective, they want to see how it performs going forward in real-world clinical settings.

"The performance of the deep learning tool seemed on par with that of radiologists," said study senior author Weichung Wang, Ph.D., professor at National Taiwan University and director of the university's MeDA Lab. "Specifically, in this study, the sensitivity of the deep learning computer-aided detection tool for pancreatic cancer was comparable with that of radiologists in a tertiary referral center regardless of tumor size and stage."

"The CAD tool may serve as a supplement for radiologists to enhance the detection of pancreatic cancer," said the study's co-senior author, Wei-Chi Liao, M.D., Ph.D., from National Taiwan University and National Taiwan University Hospital.

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69 (39.815902709961): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=215 ORDER BY `ordering`

70 (378.13186645508): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794568 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (239.13383483887): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794568 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (59.843063354492): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 1276.0162353516): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (58.889389038086): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (51.021575927734): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794568 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (39.100646972656): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794568 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (34.093856811523): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (82.015991210938): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (37.193298339844): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (116.82510375977): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

105 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

106 (77.009201049805): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294794568 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (698.08959960938): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294794568 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (162.83988952637): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

109 (53.167343139648): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

110 (66.041946411133): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294794568 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (633.00132751465): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294794568 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (767.94624328613): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (535.96496582031): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (101.80473327637): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

115 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

116 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

117 (59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

118 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

119 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

120 (351.90582275391): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 46557.188034058): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (84.161758422852): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

123 (43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

124 (476.83715820312): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794568 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794568 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 1080351.1142731): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (!!!!! 1370251.1787415): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (69.856643676758): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (30.994415283203): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (40.054321289062): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (28.133392333984): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (26.941299438477): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (320.9114074707): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (264.88304138184): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (114.91775512695): SELECT name FROM jos_deeppockets WHERE id=215

136 (30.994415283203): SELECT name FROM jos_deeppockets WHERE id=215

137 (416.99409484863): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (359.05838012695): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (954.86640930176): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

140 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

141 (!!!!! 15517.950057983): TRUNCATE TABLE jos_trademed_module

142 (288.96331787109): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294794568 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (!!!!! 1008.9874267578): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294794568 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (489.95018005371): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (349.99847412109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (300.16899108887): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

147 (326.87187194824): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

148 (!!!!! 1340.8660888672): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (272.03559875488): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

150 (274.8966217041): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

151 (!!!!! 7668.0183410645): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794568 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794568 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (277.04238891602): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

153 (229.83551025391): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

154 (435.82916259766): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (571.01249694824): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

156 (164.98565673828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794568 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794568 AND published='1' LIMIT 1

157 (426.05400085449): select jos_twitters.link from jos_twitters where cat=10

158 (222.92137145996): select jos_facebook.link from jos_facebook where cat=10

159 (46.014785766602): select jos_google_plus.link from jos_google_plus where cat=10

160 (229.83551025391): select jos_linkedin.link from jos_linkedin where cat=10

161 (760.07843017578): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 1358.9859008789): insert into jos_banners_delta values (14615,'2025-05-01 01:46:24','18.188.0.144','view'),(14202,'2025-05-01 01:46:24','18.188.0.144','view'),(14203,'2025-05-01 01:46:24','18.188.0.144','view')

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