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Digital Wrist Tomosynthesis Assesses Women’s Bone Health

By MedImaging International staff writers
Posted on 08 Feb 2021

Image: A 19-year-old woman undergoing DWT in a DBT scanner (Photo courtesy of Yener Yeni/ Henry Ford)

A new study shows how digital breast tomosynthesis (DBT) scanners can also be used to perform bone density measurements.

Researchers at Henry Ford Health System (Detroit, MI, USA) conducted a study to explore the feasibility of using DBT devices for digital wrist tomosynthesis (DWT) so as to measure bone mineral density (BMD), cortical bone thickness, and microstructural properties of the wrist bone. The results were then correlated to reference measurements acquired via microcomputed tomography and dual energy x-ray absorptiometry (DXA). The researchers recruited five patients, (19 to 75 years of age), who aligned their left hand on a generic hand template taped to a DBT machine.

The results showed that measurements from DWT imaging with a DBT scanner were highly repeatable; in ex-vivo trials, DWT derived BMDs were strongly correlated with reference measurements, as was the cortical thickness measured at lateral and medial cortices, and the majority of microstructural measures. In-vivo measurements were quick and tolerated well by the volunteer patients with no discomfort, and appeared to be different between young and old participants in a preliminary comparison. The study was published on December 13, 2021, in Bone.

“DWT is feasible in a mammography setting, and informative on bone mass, cortical thickness, and microstructural qualities that are known to deteriorate in osteoporosis. To our knowledge, this study represents the first application of DBT for imaging bone,” concluded lead author Yener Yeni, PhD, and colleagues. “It is reasonable to expect that with increasing adoption of DBT and continued high adherence to breast screening, bone screening would become more prevalent if offered in coordination with DBT breast exams.”

Osteoporosis is defined as a bone density of 2.5 standard deviations below that of a young adult, as measured by DXA. It is the most common reason for a broken bone among the elderly, and may be due to a lower than normal peak bone mass and a greater than normal bone loss. It is more common in women than men, with 2-8% of males and 9-38% of females affected after menopause, usually due to lower levels of estrogen.

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70 (!!!!! 2506.0176849365): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294786940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (!!!!! 7849.9317169189): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294786940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (!!!!! 7807.9700469971): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (638.00811767578): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (180.95970153809): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (53.882598876953): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (!!!!! 1322.9846954346): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (556.94580078125): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (831.84242248535): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (297.06954956055): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (507.83157348633): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (460.86311340332): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (331.16340637207): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (!!!!! 3120.8992004395): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (566.95938110352): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (339.98489379883): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (72.002410888672): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294786940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (59.127807617188): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294786940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (47.922134399414): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 1470.8042144775): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (77.009201049805): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (134.94491577148): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (!!!!! 1219.0341949463): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (133.03756713867): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (189.06593322754): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (118.01719665527): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (277.99606323242): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

105 (168.0850982666): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

106 (652.07481384277): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294786940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (64.13459777832): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294786940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (317.09671020508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

109 (174.99923706055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

110 (272.98927307129): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294786940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (521.89826965332): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294786940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (694.03648376465): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (386.95335388184): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (97.990036010742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

115 (64.13459777832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

116 (100.85105895996): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

117 (42.200088500977): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

118 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

119 (38.14697265625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

120 (380.03921508789): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 51952.838897705): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (229.1202545166): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

123 (231.02760314941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

124 (!!!!! 3174.0665435791): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294786940 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294786940 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 781586.88545227): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (81.062316894531): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (47.922134399414): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (44.107437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (53.882598876953): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (525.95138549805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (514.03045654297): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (304.9373626709): SELECT name FROM jos_deeppockets WHERE id=215

136 (51.021575927734): SELECT name FROM jos_deeppockets WHERE id=215

137 (560.99891662598): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (438.92860412598): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (106.0962677002): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

140 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

141 (!!!!! 9431.8389892578): TRUNCATE TABLE jos_trademed_module

142 (102.04315185547): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294786940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (57.93571472168): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294786940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (808.0005645752): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (57.220458984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

147 (44.822692871094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

148 (!!!!! 1085.9966278076): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (50.783157348633): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

150 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

151 (69.141387939453): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294786940 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294786940 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (415.08674621582): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

153 (37.193298339844): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

154 (31.948089599609): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

156 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786940 AND published='1' LIMIT 1

157 (38.862228393555): select jos_twitters.link from jos_twitters where cat=10

158 (31.948089599609): select jos_facebook.link from jos_facebook where cat=10

159 (30.040740966797): select jos_google_plus.link from jos_google_plus where cat=10

160 (30.994415283203): select jos_linkedin.link from jos_linkedin where cat=10

161 (219.82192993164): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 1355.8864593506): insert into jos_banners_delta values (14615,'2025-06-18 15:20:59','216.73.216.120','view'),(14202,'2025-06-18 15:20:59','216.73.216.120','view'),(14203,'2025-06-18 15:20:59','216.73.216.120','view')

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