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Machine Learning Aids Diagnosis and Prognosis of Prostate Cancer Using MRI

By MedImaging International staff writers
Posted on 27 Mar 2023

Conventional magnetic resonance imaging (MRI) is a reliable tool for prognosis, diagnosis, active surveillance, and reducing the need for biopsy procedures in lower-risk prostate cancer patients. The integration of open-source data with machine learning models has created new opportunities to study disease progression and regression, particularly in the medical field. However, effectively incorporating machine learning in patient care poses several challenges, such as optimizing machine learning approaches for specific cancers, ensuring adequate specificity of training data for a particular medical condition, and more. In this context, generative adversarial networks (GANs) are being explored as a potential solution for generating high-quality synthetic data that accurately represent the clinical variability of a condition and can be applied to a range of imaging technologies, including PET, CT, MRI, ultrasound, and X-ray imaging in the brain, abdomen, and chest. However, while there has been some success, the use of GAN models is currently limited when it comes to accurately depicting the heterogeneity of complex diseases like prostate cancer.

A team of translational researchers at the University of Miami Health System (Miami, FL, USA) is leading the way in improving GAN tools for integration with diagnostic and prognostic tools in prostate cancer research. By requiring less data and patient follow-ups, GAN has the potential to revolutionize machine learning models and reduce healthcare costs and patient discomfort associated with repeat follow-ups. The goal is to use GAN's machine learning capabilities to generate digital images that learn from previous MRI images and clinical parameters, and predict disease progression or regression patterns.

The research team conducted a study using prostate MRIs and digital pathology from multiple sources as training data to develop a GAN model. With deep learning, they trained the model to segment the prostate boundary on both MRI and histology slices, which provide microscopic tissue structures. Experts with different levels of experience evaluated the generated images against traditional MRI images of the prostate. The study demonstrated that the prostate cancer MRIs produced using the model were of high quality. Deep learning segmentation helped remove images with significant distortion, indicating that this GAN machine learning model for prostate cancer imaging has promising implications for complex patient cases.

“Timely diagnosis and assessment of prognosis are challenges for prostate cancer, and this results in many deaths and increases [risk of disease progression],” said Himanshu Arora, Ph.D., assistant professor at Sylvester and the Desai Sethi Urology Institute at the Miller School of Medicine. “We cannot replace the human eye when it comes to medical decision-making. Still, the improvement in technologies could potentially assist radiation oncologists in making timely decisions.”

“Technically, the technology developed here is the first start to building more sophisticated models of ‘data augmentation’ where new digital images can be used in further analysis. This is an early phase of our study, but the outcomes are extremely promising,” Dr. Arora added.

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65 (!!!!! 2441.1678314209): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

66 (391.96014404297): SELECT fid FROM jos_deeppockets WHERE id=294796648 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294796648 AND published='1' LIMIT 1

67 (215.05355834961): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

68 (46.968460083008): select jos_twitters.link from jos_twitters where cat=10

69 (26.941299438477): select jos_facebook.link from jos_facebook where cat=10

70 (26.941299438477): select jos_google_plus.link from jos_google_plus where cat=10

71 (25.98762512207): select jos_linkedin.link from jos_linkedin where cat=10

72 (28.848648071289): SELECT fid FROM jos_deeppockets WHERE id=294796648 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294796648 AND published='1' LIMIT 1

73 (33.140182495117): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

74 (144.95849609375): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

75 (130.89179992676): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

76 (40.769577026367): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

77 (44.822692871094): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (24.080276489258): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (24.080276489258): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (23.841857910156): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (24.080276489258): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (56.028366088867): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (62.942504882812): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

92 (27.894973754883): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

93 (36.001205444336): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

94 (62.942504882812): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (32.186508178711): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

107 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

108 (!!!!! 4587.8887176514): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

109 (117.06352233887): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

110 (87.976455688477): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (65.088272094727): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

113 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

114 (60.081481933594): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

115 (525.95138549805): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

116 (576.01928710938): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

117 (437.02125549316): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

118 (90.837478637695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

119 (53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

120 (97.990036010742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

121 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

122 (65.803527832031): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

123 (39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

124 (230.07392883301): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

125 (!!!!! 39229.869842529): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

126 (110.14938354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

127 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

128 (540.97175598145): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796648 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796648 AND type='deeppockets_item' AND published='1' LIMIT 1

129 (!!!!! 519574.16534424): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

130 (252.96211242676): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

131 (247.95532226562): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

132 (190.01960754395): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

133 (252.00843811035): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

134 (198.8410949707): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

135 (349.99847412109): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

136 (223.87504577637): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

137 (776.05247497559): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (868.08204650879): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

139 (231.98127746582): SELECT name FROM jos_deeppockets WHERE id=212

140 (40.054321289062): SELECT name FROM jos_deeppockets WHERE id=212

141 (541.92543029785): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (855.2074432373): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

143 (!!!!! 1350.1644134521): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

144 (99.897384643555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

145 (!!!!! 14549.016952515): TRUNCATE TABLE jos_trademed_module

146 (128.98445129395): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (119.92454528809): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796648 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

148 (514.03045654297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (!!!!! 4442.9302215576): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

150 (!!!!! 1829.8625946045): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

151 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

152 (!!!!! 1905.2028656006): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

153 (469.20776367188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

154 (52.213668823242): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

155 (313.04359436035): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796648 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796648 AND type='deeppockets_item' AND published='1' LIMIT 1

156 (!!!!! 1794.8150634766): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

157 (56.982040405273): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

158 (41.961669921875): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

159 (899.7917175293): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

160 (69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796648 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796648 AND published='1' LIMIT 1

161 (146.15058898926): select jos_twitters.link from jos_twitters where cat=10

162 (36.001205444336): select jos_facebook.link from jos_facebook where cat=10

163 (35.04753112793): select jos_google_plus.link from jos_google_plus where cat=10

164 (31.948089599609): select jos_linkedin.link from jos_linkedin where cat=10

165 (331.87866210938): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

166 (!!!!! 3866.9109344482): insert into jos_banners_delta values (14615,'2025-04-30 13:34:59','3.128.171.15','view'),(14202,'2025-04-30 13:34:59','3.128.171.15','view'),(14203,'2025-04-30 13:34:59','3.128.171.15','view')

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