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Robotic Gamma Probe Detects Cancer Intra-Operatively
By MedImaging International staff writers Posted on 27 Jan 2021
Image: The Sensei Robotic Gamma Probe (Photo courtesy of Lightpoint Medical)
A novel intra-operative probe detects sentinel lymph node (SLN) and other cancer metastases through the lymphatic system.
The Lightpoint Medical (Chesham, United Kingdom) Sensei is a tethered gamma probe designed to be used as a guide during laparoscopic biopsy procedures. The probe locates single-photon emission computed tomography (SPECT) radioligands, such as 99mTc-nanocolloid for SNL metastasis detection, or for targeted cancer metastasis antigens, such as 99mTc-PSMA (prostate specific membrane antigen) during prostate cancer surgery. The single-use, disposable probe measures just over 40mm and is attached to a three meter long lightweight cable, supporting both intra-cavity manual and robotic laparoscopic procedures.
When used with articulating graspers, the probe can provide up to six degrees of freedom, allowing for complete intra-cavity maneuverability and dexterity. The system provides clear audible notifications and is also equipped with a graphic display. It can also be integrated with the display of any surgical robotic platform. And as it is disposable, there is no need for a sterile sheath or reprocessing, eliminating the risk of cross-contamination. At the end of the procedure, the probe can be easily extracted through a standard 12mm entry port for disposal.
“Lightpoint is developing the most advanced intra-operative cancer detection technologies to meet surgeons' needs for miniaturized cancer detection tools,” said David Tuch, CEO of Lightpoint Medical. “Currently, surgeons have no way to precisely detect cancer intra-operatively. As a result, millions of patients suffer every year as cancer is frequently left behind or healthy, functional tissue is needlessly removed.”
Lymph nodes, located throughout the body, serve as biologic filters that contain immune cells to fight infection and clean the blood. When cancer cells break away from a tumor, the cells can travel through the lymph system, and SNLs help determine cancer spread. But human SNLs are only half a centimeter in size, and are difficult to discern among the surrounding tissue during surgery. Furthermore, even when surgeons are able to map the location of the nodes, there is no current technique that indicates whether or not the lymph nodes contain cancer, requiring their removal.
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AND id != 294743300
AND id != 294743301
AND id != 294743302
AND id != 294743303
AND id != 294743304
AND id != 294743305
AND id != 294743306
AND id != 294743307
AND id != 294743308
AND id != 294743309
AND id != 294743310
AND metakey != 'aacc'
ORDER BY `ordering`82
(67.949295043945): SELECT show_live FROM jos_com_show_setting LIMIT 183
(30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 184
(36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 185
(30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 186
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 187
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 188
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 189
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 190
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 191
(24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 192
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 193
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 194
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 195
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 196
(46.014785766602): SELECT fid FROM jos_deeppockets
WHERE cat=10
AND id=294786761
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 197
(26.941299438477): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294786761 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 198
(30.994415283203): SELECT id,name,title
FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
AND id != 294743300
AND id != 294743301
AND id != 294743302
AND id != 294743303
AND id != 294743304
AND id != 294743305
AND id != 294743306
AND id != 294743307
AND id != 294743308
AND id != 294743309
AND id != 294743310
AND metakey != 'aacc'
ORDER BY `ordering`99
(50.783157348633): SELECT show_live FROM jos_com_show_setting LIMIT 1100
(31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1101
(29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1102
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1103
(30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1104
(32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1105
(43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1106
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1107
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1108
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1109
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1110
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1111
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1112
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1113
(64.13459777832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1114
(41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1115
(59.843063354492): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294786761
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1116
(45.061111450195): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294786761
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1117
(64.849853515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1118
(45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1119
(356.91261291504): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294786761
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1120
(371.93298339844): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294786761
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1121
(61.988830566406): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294786760
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1122
(346.89903259277): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294786760
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1123
(808.9542388916): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1124
(513.07678222656): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1125
(187.15858459473): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1126
(59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1127
(133.03756713867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1128
(58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1129
(111.10305786133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1130
(51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1131
(380.03921508789): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`132
(!!!!! 28513.193130493): SELECT
*
FROM
jos_deeppockets
WHERE
jos_deeppockets.cat = 10
AND
jos_deeppockets.type = 'deeppockets_item'
AND
jos_deeppockets.published = 1
AND
jos_deeppockets.created + INTERVAL 14 DAY >= NOW()
ORDER BY
jos_deeppockets.hits DESC
LIMIT
7133
(134.94491577148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1134
(63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1135
(664.94941711426): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294786761 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294786761 AND type='deeppockets_item' AND published='1' LIMIT 1136
(!!!!! 452027.08244324): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3137
(91.075897216797): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3138
(385.04600524902): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800513
LIMIT 1139
(75.101852416992): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800513
LIMIT 1140
(326.15661621094): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800359
LIMIT 1141
(57.93571472168): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800359
LIMIT 1142
(225.78239440918): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800361
LIMIT 1143
(59.127807617188): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800361
LIMIT 1144
(579.1187286377): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294786761
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1145
(392.91381835938): SELECT *
FROM jos_deeppockets_archive
WHERE 1=1
AND id=294786761
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1146
(284.19494628906): SELECT name FROM jos_deeppockets WHERE id=213147
(39.815902709961): SELECT name FROM jos_deeppockets WHERE id=213148
(537.15705871582): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3149
(442.9817199707): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3150
(70.095062255859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1151
(50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1152
(!!!!! 10716.915130615): TRUNCATE TABLE jos_trademed_module153
(126.12342834473): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294786761
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1154
(81.062316894531): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294786761
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1155
(907.89794921875): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294786761
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1156
(88.930130004883): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294786761
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1157
(93.936920166016): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1158
(62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1159
(!!!!! 1391.8876647949): SELECT jos_item.*
FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
WHERE 1=1
AND (jos_item.imgMini<>'')
AND jos_item.type='L'
AND jos_item.numberID= (
SELECT jos_number.id
FROM jos_number
WHERE jos_number.journalID IN (10)
and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
LIMIT 0,1
)
ORDER BY RAND() DESC LIMIT 6160
(55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1161
(47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1162
(63.896179199219): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294786761 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294786761 AND type='deeppockets_item' AND published='1' LIMIT 1163
(656.1279296875): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=0 or channel_id is null)164
(51.021575927734): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=0 or channel_id is null)165
(52.928924560547): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1166
(550.0316619873): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1167
(117.06352233887): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294786761 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294786761 AND published='1'
LIMIT 1168
(176.90658569336): select jos_twitters.link from jos_twitters where cat=10169
(44.107437133789): select jos_facebook.link from jos_facebook where cat=10170
(38.862228393555): select jos_google_plus.link from jos_google_plus where cat=10171
(37.908554077148): select jos_linkedin.link from jos_linkedin where cat=10172
(431.06079101562): update jos_bannersmanager_banner
set impmade=impmade+1
where id in(14615,14202,14203)173
(!!!!! 1801.9676208496): insert into jos_banners_delta values (14615,'2025-05-14 05:02:22','13.58.115.236','view'),(14202,'2025-05-14 05:02:22','13.58.115.236','view'),(14203,'2025-05-14 05:02:22','13.58.115.236','view')
Expo
.jpg "Image: CT coronary angiography for diagnosing coronary artery disease offers advantages over other diagnostic tests (Photo courtesy of 123RF)")
.jpg "Image: Exemplary illustration of the labeling and segmentation process (Photo courtesy of TUM)")
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