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Compact Radiation System Delivers Conformal RT Treatments

By MedImaging International staff writers
Posted on 23 Jan 2018

Novel pencil beam scanning (PBS) technology uses hyperscanning to deliver faster, sharper, and more robust radiation therapy (RT) treatments.

The Mevion Medical Systems (Mevion; Littleton, MA, USA) S250i Proton Therapy System with Hyperscan PBS technology is designed to shape the delivered radiation dose by “painting” tumors spot-by-spot and layer-by-layer with the sub-atomic proton particles. Hyperscan technology helps overcome clinical challenges faced by first generation PBS systems by reducing delivery times to less than five seconds, thus reducing errors resulting that can undermine the high precision of PBS due to the target tumor shifting under normal organ motion, such as breathing.

In addition to Hyperscan, the system utilizes an adaptive, robotically controlled aperture proton multi-leaf collimator (pMLC), which is capable of trimming the edges of the beam at every layer of delivery. This capability can deliver up to a three times sharper drop off in radiation at the delivery field edge, sparing healthy tissue and limiting unnecessary radiation to sensitive locations. As other members of the S250 Series platform, the S250i includes a gantry mounted superconducting synchrocyclotron, a six degree-of-freedom treatment couch, and advanced in-room image guidance.

“Delivering sharp field edges has been a real challenge for PBS, especially in shallow fields. In intracranial procedures, where critical structures are in close proximity to tumors at shallow depths, having the sharpest lateral penumbra is essential,” said Skip Rosenthal, VP of clinical education at Mevion. “The sharp penumbras of the adaptive aperture system have substantial benefits for these patients. In addition, the enhanced speed of Hyperscan PBS could enable greater confidence in treating thoracic tumors.”

Proton therapy is a precise form of RT that uses charged particles instead of x-rays. It can be a more effective form of treatment than conventional radiotherapy as it directs the RT more precisely, with minimal damage to surrounding tissue. Evidence is growing that protons can be effective in treating a number of cancers, in particular in children and young people with brain tumors, for whom it appears to produce fewer side effects such as secondary cancers, growth deformity, hearing loss, and learning difficulties.

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67 (62.942504882812): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

68 (96.08268737793): select jos_twitters.link from jos_twitters where cat=10

69 (48.160552978516): select jos_facebook.link from jos_facebook where cat=10

70 (31.948089599609): select jos_google_plus.link from jos_google_plus where cat=10

71 (64.13459777832): select jos_linkedin.link from jos_linkedin where cat=10

72 (99.897384643555): SELECT fid FROM jos_deeppockets WHERE id=294772253 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294772253 AND published='1' LIMIT 1

73 (72.002410888672): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

74 (226.97448730469): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294772253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

75 (213.8614654541): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294772253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

76 (41.961669921875): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

77 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (59.843063354492): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (53.167343139648): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (139.95170593262): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (58.889389038086): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (100.13580322266): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (44.822692871094): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (263.21411132812): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294772253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

92 (61.03515625): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294772253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

93 (89.168548583984): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

94 (391.96014404297): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (191.92695617676): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (499.96376037598): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (494.95697021484): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (346.18377685547): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (270.12825012207): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (689.98336791992): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (593.90068054199): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (206.94732666016): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (195.02639770508): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (200.03318786621): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (478.02925109863): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (!!!!! 1672.0294952393): SELECT show_live FROM jos_com_show_setting LIMIT 1

107 (61.03515625): SELECT show_live FROM jos_com_show_setting LIMIT 1

108 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

109 (43.153762817383): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

110 (96.08268737793): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294772253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (72.002410888672): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294772253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (953.91273498535): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

113 (693.08280944824): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

114 (669.00253295898): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294772253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

115 (623.94142150879): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294772253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

116 (790.11917114258): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

117 (582.93342590332): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

118 (170.94612121582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

119 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

120 (79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

121 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

122 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

123 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

124 (397.92060852051): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

125 (!!!!! 52309.989929199): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

126 (113.01040649414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

127 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

128 (864.02893066406): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294772253 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294772253 AND type='deeppockets_item' AND published='1' LIMIT 1

129 (!!!!! 786796.8082428): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

130 (65.088272094727): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

131 (37.908554077148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

132 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

133 (37.908554077148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

134 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

135 (29.802322387695): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

136 (27.894973754883): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

137 (856.87637329102): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (766.03889465332): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

139 (195.98007202148): SELECT name FROM jos_deeppockets WHERE id=213

140 (38.862228393555): SELECT name FROM jos_deeppockets WHERE id=213

141 (630.85556030273): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (829.93507385254): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

143 (432.96813964844): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

144 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

145 (!!!!! 12202.024459839): TRUNCATE TABLE jos_trademed_module

146 (79.870223999023): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294772253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (46.968460083008): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294772253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

148 (757.93266296387): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

150 (202.17895507812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

151 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

152 (!!!!! 1819.1337585449): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

153 (365.01884460449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

154 (49.829483032227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

155 (178.09867858887): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294772253 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294772253 AND type='deeppockets_item' AND published='1' LIMIT 1

156 (32.901763916016): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

157 (29.087066650391): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

158 (118.97087097168): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

159 (874.04251098633): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

160 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294772253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294772253 AND published='1' LIMIT 1

161 (34.809112548828): select jos_twitters.link from jos_twitters where cat=10

162 (28.848648071289): select jos_facebook.link from jos_facebook where cat=10

163 (27.894973754883): select jos_google_plus.link from jos_google_plus where cat=10

164 (28.133392333984): select jos_linkedin.link from jos_linkedin where cat=10

165 (283.00285339355): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

166 (!!!!! 1322.9846954346): insert into jos_banners_delta values (14615,'2025-04-30 19:16:27','3.146.206.0','view'),(14202,'2025-04-30 19:16:27','3.146.206.0','view'),(14203,'2025-04-30 19:16:27','3.146.206.0','view')

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