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First-Ever Clinical CT Scanner Combines Two X-Ray Technologies to Produce 3D Dark-Field X-Ray Images

By MedImaging International staff writers
Posted on 09 Feb 2022

For the first time, researchers have integrated the dark-field X-ray method into a Computed tomography (CT) scanner suitable for clinical use.

With the new prototype developed by the team of researchers at the Technical University of Munich (Munich, Germany), it is now possible to produce three-dimensional dark-field X-ray images. Dark-field imaging provides additional information to conventional X-ray imaging. CT is one of the most important clinical methods for precise and fast diagnostics. By combining multiple X-ray images three-dimensional images of the patient are generated. With dark-field imaging now additional information on fine tissue structures, in particular in the lung, is accessible. Until now, technical challenges have prevented the integration of this new technology into clinical CT scanners to examine patients. The new CT scanner combines both X-ray technologies. The new CT prototype has already been used successfully with a thorax phantom, a model of a human upper body, and is large enough for the intended applications with real patients.

With conventional X-ray equipment, the X-rays are attenuated by the intervening tissue as they travel from the source to the detector. This effect is used to produce images based on the varying degrees of attenuation associated with different tissue types and structures. That is why bones and similar structures, which have a stronger attenuating effect, appear white in X-rays, while more transparent tissue types such as the lung produce darker images. Dark-field imaging, by contrast, makes use of the small-angle scattering of the X-rays. When the X-rays interact with materials of different densities such as the interface between lung tissue and air, they are scattered. The analysis of this scattering effect yields additional information on very fine tissue structures, which is otherwise not accessible with conventional X-ray images. To detect the scattering of the X-ray radiation, a set of three optical gratings is required. They are placed between the X-ray source and detector. When X-rays pass through these gratings, a characteristic pattern is produced at the detector. When a sample or person is then positioned in the beam path, this characteristic pattern is changed. These deviations are then used to analyze the structure of the sample or the person’s tissue.

The implementation of the dark-field method in a human-size CT scanner poses various technical challenges. Until now, this has limited dark-field CT devices to a scale much smaller than would be needed for human patients. Apart from the size, the fast rotation of the scan unit also creates special difficulties for the technical design. The scanning unit of CT scanners, known as the gantry, rotates at very high speeds. This causes vibrations that affect the finely-tuned components in the interior of the device. Based on a detailed analysis of these vibrations, the team was able to use them to implement the required shift between the gratings needed for dark-field imaging. To analyze the scans, they developed new algorithms to filter out the vibration effects based on reference scans. As the next step, the researchers plan to further optimize the dark-field CT prototype and prepare for the first scans of human patients.

“For the first time, we showed that dark-field X-ray technology can also be integrated into a clinical CT scanner. Although this technology is in its early stages, pre-clinical studies with mice have demonstrated clear benefits from dark-field CT scans, especially for capturing images of lung tissue,” said Franz Pfeiffer, Professor for Biomedical Physics and Director of the Munich Institute of Biomedical Engineering at TUM, who headed the study.

“With the dark-field CT prototype, we can capture conventional and dark-field X-ray images in a single scan. This yields additional information that could be used in the future not only to diagnose lung diseases, but also to differentiate between various types of kidney stones and tissue deposits,” added Manuel Viermetz, one of the two first authors of the study.

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62 (442.9817199707): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294791535 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

63 (!!!!! 1066.9231414795): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

64 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

65 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

66 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

67 (87.976455688477): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

68 (509.97734069824): SELECT fid FROM jos_deeppockets WHERE id=294791535 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294791535 AND published='1' LIMIT 1

69 (298.02322387695): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

70 (47.922134399414): select jos_twitters.link from jos_twitters where cat=10

71 (29.087066650391): select jos_facebook.link from jos_facebook where cat=10

72 (30.040740966797): select jos_google_plus.link from jos_google_plus where cat=10

73 (29.087066650391): select jos_linkedin.link from jos_linkedin where cat=10

74 (30.994415283203): SELECT fid FROM jos_deeppockets WHERE id=294791535 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294791535 AND published='1' LIMIT 1

75 (34.809112548828): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

76 (253.20053100586): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791535 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

77 (226.02081298828): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791535 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

78 (39.100646972656): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

79 (48.160552978516): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (43.869018554688): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791535 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

94 (30.040740966797): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791535 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

95 (31.948089599609): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

96 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

107 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

108 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

109 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

110 (58.174133300781): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

111 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

112 (67.949295043945): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294791535 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (64.13459777832): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294791535 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

114 (59.843063354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

115 (39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

116 (347.85270690918): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294791535 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

117 (344.03800964355): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294791535 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

118 (50.067901611328): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294791531 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

119 (321.86508178711): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294791531 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

120 (540.01808166504): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

121 (317.09671020508): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

122 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

123 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

124 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

125 (59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

126 (89.168548583984): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

127 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

128 (238.89541625977): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

129 (!!!!! 31219.959259033): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

130 (123.02398681641): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

131 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

132 (416.99409484863): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791535 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791535 AND type='deeppockets_item' AND published='1' LIMIT 1

133 (!!!!! 558858.15620422): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

134 (72.956085205078): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

135 (39.100646972656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

136 (28.848648071289): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

137 (92.029571533203): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

138 (48.160552978516): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

139 (47.922134399414): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

140 (44.107437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

141 (633.95500183105): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

142 (396.0132598877): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

143 (453.94897460938): SELECT name FROM jos_deeppockets WHERE id=211

144 (52.213668823242): SELECT name FROM jos_deeppockets WHERE id=211

145 (466.10832214355): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

146 (393.15223693848): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

147 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

148 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

149 (!!!!! 11363.02947998): TRUNCATE TABLE jos_trademed_module

150 (92.983245849609): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294791535 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

151 (83.92333984375): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294791535 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

152 (454.90264892578): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

153 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

154 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

155 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

156 (!!!!! 1053.8101196289): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

157 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

158 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

159 (42.915344238281): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791535 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791535 AND type='deeppockets_item' AND published='1' LIMIT 1

160 (35.04753112793): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

161 (41.007995605469): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

162 (43.153762817383): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

163 (254.15420532227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

164 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791535 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791535 AND published='1' LIMIT 1

165 (47.922134399414): select jos_twitters.link from jos_twitters where cat=10

166 (38.14697265625): select jos_facebook.link from jos_facebook where cat=10

167 (32.901763916016): select jos_google_plus.link from jos_google_plus where cat=10

168 (32.186508178711): select jos_linkedin.link from jos_linkedin where cat=10

169 (319.9577331543): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

170 (!!!!! 1199.0070343018): insert into jos_banners_delta values (14615,'2025-05-01 09:39:30','13.58.121.189','view'),(14202,'2025-05-01 09:39:30','13.58.121.189','view'),(14203,'2025-05-01 09:39:30','13.58.121.189','view')

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